Protein Alignment GluClalpha and CG8916

DIOPT Version :10

• Sequence 1: NP_001287408.1
• Gene: GluClalpha / 42350
• FlyBaseID: FBgn0024963
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Alignment Length: 535
• Identity: 147/535 - (27%)
• Similarity: 250/535 - (46%)
• Gaps: 102/535 - (19%)

  Fly    15 SLCSASLANNAKINFREKE---------KKVLDQILGAGKYDARIRPSGINGTDGPAVVRVNIFV 70
            |..|:.::|..::  |.|.         ..:|:.:|  .:|:....|:  :|...|.||:.||.:
  Fly    83 SYSSSEISNQRRV--RRKAAADMLSRNISMILENLL--KRYEQSQLPT--HGQGVPTVVQTNILI 141

  Fly    71 RSISKIDDVTMEYSVQLTFREQWTDERLKFDDIQGRLKYLTLT--EANRVWMPDLFFSNEKEGHF 133
            ||:..:.::.|:||:...||:.|.|:||.|   :|.:|.|:|:  ..:::|.||.:|.|.|....
  Fly   142 RSMGPVSELDMDYSMDCYFRQYWRDKRLSF---KGPIKSLSLSIKMLDKIWRPDTYFYNGKHSQI 203

  Fly   134 HNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWK-E 197
            |.|.:||..:|:..||.:|||:|:::...|||.|:.:|:|||.|.|.:.|||:....|::.|| :
  Fly   204 HMITVPNKLLRLDQNGGILYSMRLTIKATCPMELQNFPMDRQSCPLVIGSYGYINQQLIYEWKNQ 268

  Fly   198 GDPVQVVKNLHLPRFTLEKFLTDYCNSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVS 262
            .|.|..|..:.|.:|.|...:.....:....|::|.|.|....||...|:|||:|:||.::|::|
  Fly   269 DDAVSFVPGMTLNQFDLISMMHRNFTTVRREGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLS 333

  Fly   263 WVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFAL 327
            |||||:.:.|...||||.||::||::|.:......||.|.|..|:|.:..:...:....|||||.
  Fly   334 WVSFWIHREATSDRVSLCVTSVLTLSTISLDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFAG 398

  Fly   328 VNYASRSGSNKANMHKENMK-----------------KKRRDLEQASLDAASDLLDTDSNATFAM 375
            |:|.::.||.::...::..:                 ....|.:..:.:.:|:..:.|.|...|.
  Fly   399 VHYFTKLGSGESPQLEDQWEDICIANSLSDHAGEVDGDGEADADPFADEDSSNGSENDDNEAGAS 463

  Fly   376 ASQFARGGGQQKPLVRHPGDPLALE---------------KR------------------LQCEV 407
            .|..::.|    ..|.:..|.|.||               ||                  ::...
  Fly   464 ESVESKSG----VCVCNKNDALGLEYEVSLQNSLAGAGFLKRNAIFCPTYNDPSYILPNTMERTT 524

  Fly   408 HMQAPKRPNCCKTWL-----SKFPTRSKR---------------------IDVISRITFPLVFAL 446
            ..:.|......:.|:     :.|..:.:|                     ||.::||.||:.||.
  Fly   525 QTEPPAVSRLHQMWMCLKSDNSFRKQRERNAAAQKSEQGGANCYVNSVSLIDRVARIAFPMSFAF 589

  Fly   447 FNLVYWSTY-LFREE 460
            .||:||..| ::::|
  Fly   590 LNLLYWWAYGMYKKE 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	145/527 (28%)
CG8916	NP_573090.3	LIC	92..598	CDD:455710	142/518 (27%)
		LGIC_ECD_GABAR_GRD-like	132..314	CDD:349808	65/184 (35%)
		Cys-loop	233..247	CDD:349808	8/13 (62%)