DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GluClalpha and Gabra2

DIOPT Version :9

Sequence 1:	NP_001287408.1	Gene:	GluClalpha / 42350	FlyBaseID:	FBgn0024963	Length:	463	Species:	Drosophila melanogaster
Sequence 2:	XP_017454595.1	Gene:	Gabra2 / 289606	RGDID:	61856	Length:	504	Species:	Rattus norvegicus

Alignment Length:	453	Identity:	164/453 - (36%)
Similarity:	244/453 - (53%)	Gaps:	45/453 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 NNAKI---NFREKEKK--------VLDQILGAGKYDARIRPSGINGTDGPAVVRVNIFVRSISKI 76
            |.|::   |.:|.|.|        :||::|..  ||.|:|| |:.  |....|..||:|.|...:
  Rat    74 NPARLVLANIQEDEAKNNITIFTRILDRLLDG--YDNRLRP-GLG--DSITEVFTNIYVTSFGPV 133

  Fly    77 DDVTMEYSVQLTFREQWTDERLKFDDIQGRLKYLTLTE--ANRVWMPDLFFSNEKEGHFHNIIMP 139
            .|..|||::.:.||::|.||||||   :|.:..|.|..  |:::|.||.||.|.|:...||:.||
  Rat   134 SDTDMEYTIDVFFRQKWKDERLKF---KGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMP 195

  Fly   140 NVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLW--KEGDPVQ 202
            |..:||..:|::||::|:::...|||:|:.:|:|...|.|:..||.:||:::.::|  ...|.||
  Rat   196 NKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQ 260

  Fly   203 VVKN-LHLPRFTLEKFLTDYCNSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSF 266
            |..: ..|.::.|..........|::||||:.:......||:..|::||.|:||.|.||:|.|||
  Rat   261 VAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSF 325

  Fly   267 WLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYA 331
            ||::.:||||...||||:|||.|.:.....|||.|:|..|:|.:..||..|||.||:|||.|||.
  Rat   326 WLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYF 390

  Fly   332 SRSGSNKANMHKENMKKKRRDLEQASLDAASDLLDTDSNATFAMASQFARGGGQQKPLVRHPGDP 396
            ::.|.........|.|||    |:.|       :...:||.....:.:|....:         ||
  Rat   391 TKRGWAWDGKSVVNDKKK----EKGS-------VMIQNNAYAVAVANYAPNLSK---------DP 435

  Fly   397 LALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRSKRIDVISRITFPLVFALFNLVYWSTYLFRE 459
            : |....:.....:..|:|........|......:||.:|||.||::|..||||||:|||.||
  Rat   436 V-LSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNRE 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	159/447 (36%)
Gabra2	XP_017454595.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910