Protein Alignment GluClalpha and lgc-43

DIOPT Version :9

• Sequence 1: NP_001287408.1
• Gene: GluClalpha / 42350
• FlyBaseID: FBgn0024963
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: NP_001023062.1
• Gene: lgc-43 / 259591
• WormBaseID: WBGene00008076
• Length: 679
• Species: Caenorhabditis elegans
• Alignment Length: 467
• Identity: 109/467 - (23%)
• Similarity: 192/467 - (41%)
• Gaps: 97/467 - (20%)

  Fly    18 SASLANNAKINFREK--------EKKVLDQ----------ILGAGKYDARIRPSGINGTDGPAVV 64
            |..|.:..:.::|:|        |::..:.          :|.:..||....|...|  |.|..|
 Worm   284 SVRLTSQQRSDWRDKLTNLTMLEERRANEHRDYGSSYILPVLKSVDYDNTSVPLAFN--DIPVNV 346

  Fly    65 RVNIFVRSISKIDDVTMEYSVQLTFREQWTDERLKFDDIQGRLKYLTLTE---ANRVWMPDLFFS 126
            .|......::..|...||:|:.:.....|.|.||    :....|.:.:.|   ..::|.||.:..
 Worm   347 AVAFNFLYLANFDSEMMEFSMDVEMEFSWIDIRL----VNNYTKPIRIREKPIIEQIWRPDPYIV 407

  Fly   127 NEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDL 191
            |.|..:||.:..||:.:||.|.|.|.|::|:|...:|.|:..|||.|||.|.||::|..::...:
 Worm   408 NSKHSYFHYVSFPNIRMRITPEGLVTYTVRVSSVCSCFMSFCLYPHDRQECDLRISSIAYSNQYV 472

  Fly   192 VFLWKEGDPVQVVKNLHLPRFTLEKFLTDYCNSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCC 256
            .|.| ..:|::....:.||...:.|..|..|::|....:.|||::....:|:.:.::|:.|:|..
 Worm   473 KFHW-HSNPIKFQSKITLPELHITKIKTAECSTKGKLVDASCLRIIFSLERDSARFVIEKYVPST 536

  Fly   257 MLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGA 321
            :.::.:||:.::.......|:...:|.|||:.....|....  ..||..:||||.....:|...:
 Worm   537 LAMMFAWVAPYVPYNYEDVRIITPITVLLTLVQMEKGDKEI--RTSYLTSIDVWFAAMKSFTVLS 599

  Fly   322 LLE-FALVNYASRSGSNKANMHKENMKKKRRDLEQASLDAASDLLDTDSNATFAMASQFARGGGQ 385
            ||| .|::....||.:    |.| |.::...:.|:.:.:|.:
 Worm   600 LLESLAVLALIKRSRA----MTK-NAERAANEFERCTFEAEA----------------------- 636

  Fly   386 QKPLVRHPGDPLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRSKRIDVISRITFPLVFALFNLV 450
                           .||....|                      |:|.|.|.:.|:||..| .|
 Worm   637 ---------------YRLNRLYH----------------------RVDSICRFSSPVVFVAF-FV 663

  Fly   451 YWSTYLFREEED 462
            |:..::.:..|:
 Worm   664 YYVLFVAQGNEN 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	108/458 (24%)
lgc-43	NP_001023062.1	LGIC_ECD_anion	344..523	CDD:349788	53/183 (29%)
		LGIC_TM	527..665	CDD:365787	41/205 (20%)
		TM1 helix	527..551	CDD:349850	5/23 (22%)
		TM2 helix	555..577	CDD:349850	6/21 (29%)
		TM3 helix	583..609	CDD:349850	9/25 (36%)
		TM4 helix	610..665	CDD:349850	19/120 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D614790at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020