Protein Alignment GluClalpha and GABRR1

DIOPT Version :9

• Sequence 1: NP_001287408.1
• Gene: GluClalpha / 42350
• FlyBaseID: FBgn0024963
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: NP_002033.2
• Gene: GABRR1 / 2569
• HGNCID: 4090
• Length: 479
• Species: Homo sapiens
• Alignment Length: 444
• Identity: 152/444 - (34%)
• Similarity: 245/444 - (55%)
• Gaps: 67/444 - (15%)

  Fly    38 DQILGAGKYDARIRPSGINGTDGPAV-VRVNIFVRSISKIDDVTMEYSVQLTFREQWTDERLKFD 101
            :|:|....:|..:||    |..|||: |.|::.|.|:..|.:|.|::::.|..|..|.||||.|.
Human    76 EQLLRIDDHDFSMRP----GFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFP 136

  Fly   102 D-------IQGRLKYLTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISL 159
            .       ..|||       ..::|:||:||.:.|....|:....||.:|:.|:|.||||:|:::
Human   137 STNNLSMTFDGRL-------VKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTV 194

  Fly   160 TLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEG-DPVQVVKNLHLPRFTLEKFLTDYCN 223
            |..|.|:...:|||.|.|||.:.||.:|.:||:..||:| |.::..:.:.|.:|.:::|.|   .
Human   195 TAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHT---T 256

  Fly   224 SK----TNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTL 284
            :|    ::||.|:.|.::...:|...::|:|.|.|..::|::||||||:|:.||||||.||:||:
Human   257 TKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTV 321

  Fly   285 LTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSGSNKANMHKENMKKK 349
            |||:|..:|:|||:|.|||.||:|::..|...|||.::||:|.|||.:       .:.:...:|.
Human   322 LTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLT-------TVQERKEQKL 379

  Fly   350 RRDL---------EQASLD---AASDLLDTDSNATFAMASQFARGGGQQKPLVRHPGDPLALEKR 402
            |..|         ..|.||   :..::.|.|:         :....| :||      |.:.::..
Human   380 REKLPCTSGLPPPRTAMLDGNYSDGEVNDLDN---------YMPENG-EKP------DRMMVQLT 428

  Fly   403 LQCEVHMQAPKRPNCCKTWLS-KFPTRSKRIDVISRITFPLVFALFNLVYWSTY 455
            |..|  ..:|:|.:...:::| :..|.:  ||..|||.||..:.||||:|||.:
Human   429 LASE--RSSPQRKSQRSSYVSMRIDTHA--IDKYSRIIFPAAYILFNLIYWSIF 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	152/442 (34%)
GABRR1	NP_002033.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	32..55
		LIC	75..478	CDD:273305	152/442 (34%)
		Neur_chan_LBD	76..281	CDD:280998	73/218 (33%)
		Neur_chan_memb	288..475	CDD:280999	74/213 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910