Protein Alignment GluClalpha and Gabrb2

DIOPT Version :10

• Sequence 1: NP_001287408.1
• Gene: GluClalpha / 42350
• FlyBaseID: FBgn0024963
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: XP_008765857.1
• Gene: Gabrb2 / 25451
• RGDID: 2650
• Length: 506
• Species: Rattus norvegicus
• Alignment Length: 521
• Identity: 172/521 - (33%)
• Similarity: 264/521 - (50%)
• Gaps: 94/521 - (18%)

  Fly     6 YF--WAI-LYFASLCSASLANNAKINFREKEKKVLDQILGAGKYDARIRPSGINGTDGPAVVRVN 67
            ||  |:. |..|::|:.|:.:.:.::.   .|:.:|::|..  ||.|:||. ..|.  |..|.:|
  Rat     9 YFGIWSFPLIIAAVCAQSVNDPSNMSL---VKETVDRLLKG--YDIRLRPD-FGGP--PVAVGMN 65

  Fly    68 IFVRSISKIDDVTMEYSVQLTFREQWTDERLKFDDIQGRLKYLTLTEANRV----WMPDLFFSNE 128
            |.:.||..:.:|.|:|::.:.|::.|.|:||.::.|.     |.||..|||    |:||.:|.|:
  Rat    66 IDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIP-----LNLTLDNRVADQLWVPDTYFLND 125

  Fly   129 KEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVF 193
            |:...|.:.:.|..||:.|:|:|||.:||:.|.||.|:|:.||||.|.|:|.:.|||:||:|:.|
  Rat   126 KKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 190

  Fly   194 LWKEGD-PVQVVKNLHLPRFTLEKFLTDY--CNSKT--NTGEYSCLKVDLLFKREFSYYLIQIYI 253
            .|:..| .|..|..:.||:|:    :.||  ...|.  :||.|..|.:....||...|:::|.|:
  Rat   191 YWRGDDNAVTGVTKIELPQFS----IVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYM 251

  Fly   254 PCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFV 318
            |..::.|:||||||::..|..|||:||:||:|||.|..:.:..:||.:.|.||||::...|..||
  Rat   252 PSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFV 316

  Fly   319 FGALLEFALVNY---------ASRSGSNKANMHKENMK-----------KKRRDL---------- 353
            |.||||:|||||         ..::....||.:.|.|:           |:.|..
  Rat   317 FMALLEYALVNYIFFGRGPQRQKKAAEKAANANNEKMRLDVNKIFYKDIKQNRTQYQSLWDPTRW 381

  Fly   354 --------------------------EQASLDAASDLLDTDSN--ATFAMASQFARGGGQQKPLV 390
                                      |.|:.:|...|.|..|.  |..|.:.|:.:.|     |.
  Rat   382 TTYYHFSLYMMDPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQYRKAG-----LP 441

  Fly   391 RHPGDPLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRSKRIDVISRITFPLVFALFNLVYWSTY 455
            ||.....|||:.: .:...:..:|.:..|..:... |....||..|||.||:||:.||:|||..|
  Rat   442 RHSFGRNALERHV-AQKKSRLRRRASQLKITIPDL-TDVNAIDRWSRIFFPVVFSFFNIVYWLYY 504

  Fly   456 L 456
            :
  Rat   505 V 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	171/518 (33%)
Gabrb2	XP_008765857.1	LIC	9..504	CDD:455710	171/518 (33%)