Protein Alignment GluClalpha and lgc-40

DIOPT Version :9

• Sequence 1: NP_001287408.1
• Gene: GluClalpha / 42350
• FlyBaseID: FBgn0024963
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: NP_508428.2
• Gene: lgc-40 / 188854
• WormBaseID: WBGene00020767
• Length: 494
• Species: Caenorhabditis elegans
• Alignment Length: 496
• Identity: 156/496 - (31%)
• Similarity: 239/496 - (48%)
• Gaps: 75/496 - (15%)

  Fly    17 CSASLANNAKINFREKEKKVLDQILGAGKYDARIRPSGINGTDGPAVVRVNIFVRSISKIDDVTM 81
            |..::..:|.:.|....|..||::.....|:....|:..:|.  |..|.:::|:..:|.....||
 Worm    15 CIVNVFESADLAFIPLTKAFLDKLKNETLYNRFATPTQYDGV--PTNVTLSMFIEGMSSFSAQTM 77

  Fly    82 EYSVQLTFREQWTDERLKFDDIQGRLKYLTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIF 146
            :|.:.:.|:|:|.|.||. .:....:....||....:|.||::|:|.:...|.:|...|..:.::
 Worm    78 DYHLDVYFQEEWYDHRLA-HNASAPILVRDLTVFKMMWHPDVYFANARSAAFQDITDDNFLVWVY 141

  Fly   147 PNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVV---KNLH 208
            |||.|.|..|||:..:|.|:|..||||.|.|:||:.||.:....|..||.|.:.|..:   .::.
 Worm   142 PNGRVWYDARISIVSSCNMDLWKYPLDSQECALRILSYAYPMTVLRLLWSEKEDVPAIDRNPDIT 206

  Fly   209 LPRFTLEKFLTDYCNSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAV 273
            :|..:|:...|.|||....|||:||:......:||..::::|.|:|..::|::||.:|||:..:.
 Worm   207 MPDMSLKHIRTGYCNGTYATGEWSCMTAIFYVEREMMHHVMQTYVPTALIVVISWFNFWLEIDSA 271

  Fly   274 PARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSGSNK 338
            ||||||.:|||||::||.:.:..:||.|||.||||||.|.|:.||||.::||.:.:||
 Worm   272 PARVSLSITTLLTISTQANAVKLALPEVSYMKAIDVWMGSCMAFVFGVMIEFTICHYA------- 329

  Fly   339 ANMHKENMKKKRRDLEQASL----------DAASDLLDTDSNATFAMASQFARGGGQQ------- 386
                 :|::..|.| .|.||          .||.|:.|...........:..||.|:|
 Worm   330 -----KNLEMLRGD-GQPSLIVDTALSTLFGAARDIDDLVRKVATLNEEEGVRGDGEQHIALNML 388

  Fly   387 ---KPLVR---HPGDPLALEKRLQCEVHMQAPKRPNCCKTWLSKFP------------------- 426
               :|.:|   ...|..|...|..........||   .|..||:..
 Worm   389 NPEEPRLRSLNQNNDVTANGTRYFVGAERMKRKR---SKASLSRLRQQVASMRHATIDVSRRAFN 450

  Fly   427 -TR----------SKRIDVISRITFPLVFALFNLVYWSTYL 456
             ||          ::|||...||.||::|.|||:.|||.||
 Worm   451 WTRALRNLRGRRVAQRIDERCRIVFPMIFLLFNVAYWSFYL 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	154/493 (31%)
lgc-40	NP_508428.2	LIC	9..490	CDD:273305	154/493 (31%)
		Neur_chan_LBD	44..242	CDD:280998	64/200 (32%)
		Neur_chan_memb	249..487	CDD:280999	79/253 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3705
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276914at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.970