Protein Alignment GluClalpha and lgc-41

DIOPT Version :9

• Sequence 1: NP_001287408.1
• Gene: GluClalpha / 42350
• FlyBaseID: FBgn0024963
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: NP_001360683.1
• Gene: lgc-41 / 183331
• WormBaseID: WBGene00008022
• Length: 567
• Species: Caenorhabditis elegans
• Alignment Length: 570
• Identity: 156/570 - (27%)
• Similarity: 242/570 - (42%)
• Gaps: 135/570 - (23%)

  Fly     7 FWAILY-FASLCSASLANNAKINFREKEKKVLDQILGAGKYDARIRPSGINGTDGPAVVRVNIFV 70
            :|:.|: |..||.......:....:.....:|.|        :..||...|.: .|..|::.:::
 Worm     4 YWSTLHLFQVLCIFIFIRTSSPLTQPNIYNLLQQ--------SNTRPPTANAS-VPLGVKLGMYL 59

  Fly    71 RSISKIDDVTMEYSVQLTFREQWTDERL--KFDDIQGRLKYLTLTE---ANRVWMPDLFFSNEKE 130
            .|:.......|.:.|.|.....|.|.||  .|.|      |:.:..   ..::|:|||:|:|.::
 Worm    60 ESLGNFRSSEMSFDVDLYVYMSWQDPRLAHNFSD------YVLINNDEIRKQIWLPDLYFANARQ 118

  Fly   131 GHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLW 195
            ..|..:.:||..:.:.|:|:|.||.|.:||:||.:||:.||:|:|:||:|:.||.:....:...|
 Worm   119 ASFQEVTVPNFNLFVAPDGTVAYSCRCTLTVACSLNLRYYPMDQQLCSIRVLSYAYIAKQVNVTW 183

  Fly   196 KEGDPVQVVKNLHLPRFTLEKFLTDYCN---------SKTNTGEYSCLKVDLLFKREFSYYLIQI 251
            .:.:||:..:.:.||.|.:|.....|||         :...:.::|||..:|...|...|.|:|.
 Worm   184 FDKNPVRFNEEIGLPEFQIEHVSNAYCNGSYQYALTENSYKSDDFSCLSGNLFLSRSIGYNLVQS 248

  Fly   252 YIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLT 316
            |||..::|::||||||:|:.||||||:|..|||:::.|..:|:...||.|||.||||:|.|.|:.
 Worm   249 YIPTGLIVMISWVSFWIDRRAVPARVTLSFTTLVSLTTLGNGLRFGLPQVSYAKAIDLWYGACMF 313

  Fly   317 FVFGALLEFALVNYASRSGSNKANMHKEN----MKKKRRDLEQASL--------DAASDLLD--T 367
            |||.||||||.:|...|......:|.|:.    :..:.||.....:        .||.:::|  .
 Worm   314 FVFCALLEFATINSYMRKSEKFDSMAKKMQSVVLTGRTRDYLVRGIKESMRIAGGAAGNVVDALN 378

  Fly   368 DSNATF----------AMASQ-FARGGGQQKP------------LVRHPGDPLALEKRLQCEVH- 408
            |...|:          ||... |.|.|....|            ..|..|.|..::..|...:.
 Worm   379 DDWCTYSTENGRKSFSAMVGDIFERAGNAISPRRNRYRGLKTEKSPRGYGKPDTVQDILSERIKF 443

  Fly   409 --------------------MQAPKRPNCCK------TWLSKFPTRSKR---------------- 431
                                |......:|.|      :..:||.|:.||
 Worm   444 IDNEFDFDTKEDDEIPGNMAMSIYDNVSCRKDEADSSSEETKFSTKPKRNGTNGTRKYIDKSLNQ 508

  Fly   432 -------------------------IDVISRITFPLVFALFNLVYWSTYL 456
                                     ||...|..||..|.|:|:.||..||
 Worm   509 SGQNDSLIVATYFQISANHSRHALKIDKSCRYLFPAAFLLWNVFYWWYYL 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	154/567 (27%)
lgc-41	NP_001360683.1	LIC	41..>332	CDD:273305	110/297 (37%)
		LGIC_TM	<527..557	CDD:365787	10/29 (34%)
		TM4 helix	530..554	CDD:349850	8/23 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276914at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020