Protein Alignment GluClalpha and mod-1

DIOPT Version :10

• Sequence 1: NP_001287408.1
• Gene: GluClalpha / 42350
• FlyBaseID: FBgn0024963
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: NP_741580.1
• Gene: mod-1 / 179269
• WormBaseID: WBGene00003386
• Length: 489
• Species: Caenorhabditis elegans
• Alignment Length: 446
• Identity: 123/446 - (27%)
• Similarity: 207/446 - (46%)
• Gaps: 76/446 - (17%)

  Fly    64 VRVNIFVRSISKIDDVTMEYSVQLTFREQWTDERLKFDDIQGRLKYLTLTE--ANRVWMPDLFFS 126
            |.:.|.|:.:..:::::.::.:.:.|.:.|.|..|.|..:....:.:|:..  ..::|.|:....
 Worm    58 VNIEIHVQDMGSLNEISSDFEIDILFTQLWHDSALSFAHLPACKRNITMETRLLPKIWSPNTCMI 122

  Fly   127 NEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDL 191
            |.|....|.....||.:.::.||:|..:.|:|:...|.::|:.:|.|.|.|.|...||...:.::
 Worm   123 NSKRTTVHASPSENVMVILYENGTVWINHRLSVKSPCNLDLRQFPFDTQTCILIFESYSHNSEEV 187

  Fly   192 VFLWKEGDPVQVVKNLHLPRFTLEKFLTDYCNSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCC 256
            ...|.| :.|.::|.:.||.|.:..:.|.........|.:..|:|...|||.:.:|:||.|:|..
 Worm   188 ELHWME-EAVTLMKPIQLPDFDMVHYSTKKETLLYPNGYWDQLQVTFTFKRRYGFYIIQAYVPTY 251

  Fly   257 MLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGA 321
            :.:|||||||.::..|:|||.::|:::||.:..|...|..:||.|||.||:|||...|::||||.
 Worm   252 LTIIVSWVSFCMEPKALPARTTVGISSLLALTFQFGNILKNLPRVSYVKAMDVWMLGCISFVFGT 316

  Fly   322 LLEFALVNYASRSGSNKANMHKENMKKKRRDLEQASLDAASDLLDTDSNATFAMASQFARGGGQQ 386
            ::|.|.|.|.||..::..|      .::||:..:.|...|:....|.||.       :|.||.
 Worm   317 MVELAFVCYISRCQNSVRN------AERRRERMRNSQVWANGSCRTRSNG-------YANGGS-- 366

  Fly   387 KPLVRH-----------------------------PGDPLAL----------------------E 400
              ::.|                             |..||.|                      :
 Worm   367 --VISHYHPTSNGNGNNNRHDTPQVTGRGSLHRNGPPSPLNLQMTTFDSEIPLTFDQLPVSMESD 429

  Fly   401 KRLQCEVHMQAPKRPNCCKTWLSKFPTRSKRIDVISRITFPLVFALFNLVYWSTYL 456
            :.|..|:...:|..|:.|   |::|  ..:.:|..|.:.|||.|.:||||||..||
 Worm   430 RPLIEEMRSTSPPPPSGC---LARF--HPEAVDKFSIVAFPLAFTMFNLVYWWHYL 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	121/443 (27%)
mod-1	NP_741580.1	LIC	7..479	CDD:455710	121/443 (27%)
		LGIC_ECD_GABAAR	56..238	CDD:349791	43/180 (24%)
		Cys-loop	159..173	CDD:349791	5/13 (38%)