Protein Alignment GluClalpha and lgc-37

DIOPT Version :9

• Sequence 1: NP_001287408.1
• Gene: GluClalpha / 42350
• FlyBaseID: FBgn0024963
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: NP_499662.2
• Gene: lgc-37 / 176694
• WormBaseID: WBGene00013914
• Length: 483
• Species: Caenorhabditis elegans
• Alignment Length: 491
• Identity: 148/491 - (30%)
• Similarity: 241/491 - (49%)
• Gaps: 78/491 - (15%)

  Fly     4 GHYFWAILYF--ASLCSASLA-NNAKINFREKEKKVLDQILGAGKYDARIRPSGINGTDGPAVVR 65
            ||:..|::..  ..|.|.|.. |...|.:   ..||||.||  ...|...||  :|..:.|..|.
 Worm    15 GHHSQAVIDMKRQRLSSRSTTYNQTLIRY---TTKVLDTIL--LNQDKNFRP--VNPDNSPLQVE 72

  Fly    66 VNIFVRSISKIDDVTMEYSVQLTFREQWTDERLKFDDIQGRLKYLTLTE--ANRVWMPDLFFSNE 128
            |:|.:||:..:.:..||:|:...||::|.|.||.|..|......:.|..  ...:|:||.:..|.
 Worm    73 VDISIRSMGPVSEQNMEFSLDCYFRQKWLDRRLAFTPINPSKPEIPLASKMLKDIWIPDTYIRNG 137

  Fly   129 KEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVF 193
            ::.:.|.:.:||:..|:..:|.|..|.|:::...|.|.||.:|:|.|.|.:.:.|.|:.:.|:|:
 Worm   138 RKSYLHTLTVPNILFRVRSDGQVHVSQRLTIRSRCQMFLKKFPMDTQACPIEVGSLGYFSKDVVY 202

  Fly   194 LWKE-------GDPVQVVKNLHLPRFTLEKFLTDYCNSKTNTGEYSCLKVDLLFKREFSYYLIQI 251
            .||:       |:.:...:.|.|.:  .|:.::|:..|..|   .|.|.|....:|:..||::||
 Worm   203 KWKDVELDAKMGNTLSQYQVLSLSK--SERNVSDFRFSDRN---ISVLNVYFKLQRQQGYYILQI 262

  Fly   252 YIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLT 316
            |.||.::|::||||||:::.|.|||||||:.|:|:|:|...|:...||.||::.|:||:...|..
 Worm   263 YTPCTLVVVMSWVSFWINKEASPARVSLGIMTVLSMSTIGFGLRTDLPKVSHSTALDVYILTCFV 327

  Fly   317 FVFGALLEFALVNYASRSGSNKANMHKENMKKKRRDLEQASLDAASDLLDTDSNATFAMASQFAR 381
            |:|.|::|:|::|||......| .:|                    ||...:.|.  ||...|..
 Worm   328 FLFAAMVEYAVINYAQIVYIRK-QIH--------------------DLKGLEQNT--AMGQMFTA 369

  Fly   382 G--GGQQKPLVRHPGDPLALEKRLQCEVHMQA-PKRPNCC----------------KTWLSKFPT 427
            |  |.:::..::  .|.|.:||.   |..::| |.....|                |..::|...
 Worm   370 GLMGARRRDTIQ--VDDLTVEKE---EARLKAVPWWKKLCFKDEQGNTSMFYRMAVKAAIAKKTL 429

  Fly   428 RS-------KRIDVISRITFPLVFALFNLVYWSTYL 456
            |:       .:||..|::.||.::.:||:.||..||
 Worm   430 RNGDPAEVVNKIDNFSKLAFPTLYIIFNVFYWVAYL 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	146/488 (30%)
lgc-37	NP_499662.2	LIC	44..464	CDD:273305	138/456 (30%)
		Neur_chan_LBD	45..254	CDD:280998	64/217 (29%)
		Neur_chan_memb	262..461	CDD:280999	68/226 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910