Protein Alignment GluClalpha and Gabrr1

DIOPT Version :10

• Sequence 1: NP_001287408.1
• Gene: GluClalpha / 42350
• FlyBaseID: FBgn0024963
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: NP_032101.3
• Gene: Gabrr1 / 14408
• MGIID: 95625
• Length: 480
• Species: Mus musculus
• Alignment Length: 446
• Identity: 152/446 - (34%)
• Similarity: 242/446 - (54%)
• Gaps: 71/446 - (15%)

  Fly    38 DQILGAGKYDARIRPSGINGTDGPAV-VRVNIFVRSISKIDDVTMEYSVQLTFREQWTDERLKFD 101
            :|:|....:|..:||    |..|||: |.|::.|.|:..|.:|.|::::.|..|..|.||||.|.
Mouse    77 EQLLRIDDHDFSMRP----GFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFP 137

  Fly   102 D-------IQGRLKYLTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISL 159
            .       ..|||       ..::|:||:||.:.|....|:....||.:|:.|:|.||||:|:::
Mouse   138 SSNNLSMTFDGRL-------VKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTV 195

  Fly   160 TLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEG-DPVQVVKNLHLPRFTLEKFLTDYCN 223
            |..|.|:...:|||.|.|||.:.||.:|.:||:..||:| |.::..:.:.|.:|.:::|.|   .
Mouse   196 TAMCNMDFSRFPLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHT---T 257

  Fly   224 SK----TNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTL 284
            :|    ::||.|:.|.::...:|...::|:|.|.|..::|::||||||:|:.||||||.||:||:
Mouse   258 TKLAFYSSTGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTV 322

  Fly   285 LTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSGSNKANMHKENMKKK 349
            |||:|..:|:|||:|.|||.||:|::..|...|||.::||:|.|||          :.....:|:
Mouse   323 LTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNY----------LTTVQERKE 377

  Fly   350 RRDLEQASLDAA-----SDLLDTDSNATFAMASQFARG-----GGQ-----QKPLVRHPGDPLAL 399
            |:..|:.|....     ..:||          |.::.|     ||.     :||      |.:.:
Mouse   378 RKLREKISCTCGLPQPRGVMLD----------SSYSDGEVNDLGGYMPENGEKP------DRMMV 426

  Fly   400 EKRLQCEVHMQAPKRPNCCKTWLSKFPTRSKRIDVISRITFPLVFALFNLVYWSTY 455
            :..|..|  ..:|:|.....:::| ....:..||..|||.||..:.||||:|||.:
Mouse   427 QLTLASE--RGSPQRKGQRGSYVS-MRINTHAIDKYSRIIFPAAYILFNLIYWSIF 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	152/444 (34%)
Gabrr1	NP_032101.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	29..67
		LIC	76..479	CDD:455710	152/444 (34%)
		LGIC_ECD_GABAAR_rho	97..282	CDD:349806	65/194 (34%)
		Cys-loop	199..213	CDD:349806	6/13 (46%)