Protein Alignment GluClalpha and Gabra2

DIOPT Version :9

• Sequence 1: NP_001287408.1
• Gene: GluClalpha / 42350
• FlyBaseID: FBgn0024963
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: NP_032092.1
• Gene: Gabra2 / 14395
• MGIID: 95614
• Length: 451
• Species: Mus musculus
• Alignment Length: 445
• Identity: 162/445 - (36%)
• Similarity: 240/445 - (53%)
• Gaps: 42/445 - (9%)

  Fly    28 NFREKEKK--------VLDQILGAGKYDARIRPSGINGTDGPAVVRVNIFVRSISKIDDVTMEYS 84
            |.:|.|.|        :||::|..  ||.|:|| |:.  |....|..||:|.|...:.|..|||:
Mouse    29 NIQEDEAKNNITIFTRILDRLLDG--YDNRLRP-GLG--DSITEVFTNIYVTSFGPVSDTDMEYT 88

  Fly    85 VQLTFREQWTDERLKFDDIQGRLKYLTLTE--ANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFP 147
            :.:.||::|.||||||   :|.:..|.|..  |:::|.||.||.|.|:...||:.|||..:||..
Mouse    89 IDVFFRQKWKDERLKF---KGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQD 150

  Fly   148 NGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLW--KEGDPVQVVKN-LHL 209
            :|::||::|:::...|||:|:.:|:|...|.|:..||.:||:::.::|  ...|.|||..: ..|
Mouse   151 DGTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRL 215

  Fly   210 PRFTLEKFLTDYCNSKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVP 274
            .::.|..........|::||||:.:......||:..|::||.|:||.|.||:|.|||||::.:||
Mouse   216 NQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVP 280

  Fly   275 ARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSGSNKA 339
            ||...||||:|||.|.:.....|||.|:|..|:|.:..||..|||.||:|||.|||.::.|....
Mouse   281 ARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWD 345

  Fly   340 NMHKENMKKKRRDLEQASLDAASDLLDTDSNATFAMASQFARGGGQQKPLVRHPGDPLALEKRLQ 404
            .....|.|||    |:.|       :...:||.....:.:|....:         ||: |....:
Mouse   346 GKSVVNDKKK----EKGS-------VMIQNNAYAVAVANYAPNLSK---------DPV-LSTISK 389

  Fly   405 CEVHMQAPKRPNCCKTWLSKFPTRSKRIDVISRITFPLVFALFNLVYWSTYLFRE 459
            .....:..|:|........|......:||.:|||.||::|..||||||:|||.||
Mouse   390 SATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGTFNLVYWATYLNRE 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	157/439 (36%)
Gabra2	NP_032092.1	LIC	25..440	CDD:273305	157/439 (36%)
		LGIC_ECD_GABAAR_A2	47..249	CDD:349836	74/209 (35%)
		Cys-loop	166..180	CDD:349836	6/13 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	389..408		2/18 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910