Protein Alignment GluClalpha and Gabra1

DIOPT Version :9

• Sequence 1: NP_001287408.1
• Gene: GluClalpha / 42350
• FlyBaseID: FBgn0024963
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: XP_006532258.1
• Gene: Gabra1 / 14394
• MGIID: 95613
• Length: 553
• Species: Mus musculus
• Alignment Length: 481
• Identity: 166/481 - (34%)
• Similarity: 250/481 - (51%)
• Gaps: 60/481 - (12%)

  Fly     2 GSGHYFWA-ILYFASLCSASLANNAKINFREKE---KKVLDQILGAGKYDARIRPS-GINGTDGP 61
            |...|.|| .|..::|...|....::...::..   .::||::|..  ||.|:||. |...|:
Mouse   104 GLSDYLWAWTLILSTLSGRSYGQPSQDELKDNTTVFTRILDRLLDG--YDNRLRPGLGERVTE-- 164

  Fly    62 AVVRVNIFVRSISKIDDVTMEYSVQLTFREQWTDERLKFDDIQGRLKYLTLTE--ANRVWMPDLF 124
              |:.:|||.|...:.|..|||::.:.||:.|.||||||   :|.:..|.|..  |:::|.||.|
Mouse   165 --VKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKF---KGPMTVLRLNNLMASKIWTPDTF 224

  Fly   125 FSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTN 189
            |.|.|:...||:.|||..:||..:|::||::|:::...|||:|:.:|:|...|.|:..||.:|..
Mouse   225 FHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRA 289

  Fly   190 DLVFLWKEGDPVQVV----KNLHLPRFTLEKFLTDYCNSKTNTGEYSCLKVDLLFKREFSYYLIQ 250
            ::|:.|.. :|.:.|    ....|.::.|.....|....:::||||..:......||:..|::||
Mouse   290 EVVYEWTR-EPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQ 353

  Fly   251 IYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCL 315
            .|:||.|.||:|.|||||::.:||||...||||:|||.|.:.....|||.|:|..|:|.:..||.
Mouse   354 TYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCY 418

  Fly   316 TFVFGALLEFALVNYASRSG---------SNKANMHKENMKKKRRDLEQASLDAASDLLDTDSN- 370
            .|||.||:|||.|||.::.|         ..|....|:.:.||.......:.....:|...|..
Mouse   419 AFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGL 483

  Fly   371 ATFAMASQFARGGGQQKPLVRHPGDPLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRSKRIDVI 435
            ||.|.::..               :|    |.::.|.....||     ||:.|     ..:||.:
Mouse   484 ATIAKSATI---------------EP----KEVKPETKPPEPK-----KTFNS-----VSKIDRL 519

  Fly   436 SRITFPLVFALFNLVYWSTYLFREEE 461
            |||.|||:|.:||||||:|||.||.:
Mouse   520 SRIAFPLLFGIFNLVYWATYLNREPQ 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	160/472 (34%)
Gabra1	XP_006532258.1	LIC	105..539	CDD:273305	160/472 (34%)
		LGIC_ECD_GABAAR_A1	153..346	CDD:349835	68/200 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910