Protein Alignment GluClalpha and gabra2a

DIOPT Version :9

• Sequence 1: NP_001287408.1
• Gene: GluClalpha / 42350
• FlyBaseID: FBgn0024963
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: XP_009305482.1
• Gene: gabra2a / 100150704
• ZFINID: ZDB-GENE-141216-16
• Length: 451
• Species: Danio rerio
• Alignment Length: 468
• Identity: 165/468 - (35%)
• Similarity: 243/468 - (51%)
• Gaps: 53/468 - (11%)

  Fly     5 HYFWAILYFASLCSA-------SLANNAKINFREKEKKVLDQILGAGKYDARIRPSGINGTDGPA 62
            |.|..:|:.|  ||.       :..||..:..|     :||::|..  ||.|:|| |:.  |...
Zfish    14 HLFLLVLWRA--CSEAEVSGSDAFKNNITLFTR-----ILDRLLDG--YDNRLRP-GLG--DRVT 66

  Fly    63 VVRVNIFVRSISKIDDVTMEYSVQLTFREQWTDERLKFDDIQGRLKYLTLTE--ANRVWMPDLFF 125
            .|:.:|:|.|...:.|..|||:|.:.||::||||||||   .|.:..|.|..  |:::|.||.||
Zfish    67 EVKTDIYVTSFGPVSDTDMEYTVDVFFRQRWTDERLKF---HGPMNILRLNNLMASKIWTPDTFF 128

  Fly   126 SNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTND 190
            .|.|:...||:.|||..:||..||::||::|:::...|||:|:.:|:|...|.|:..||.:|..:
Zfish   129 HNGKKSVAHNMTMPNKLLRIMENGTLLYTMRLTVQAECPMHLEDFPMDFHSCPLKFGSYAYTLTE 193

  Fly   191 LVFLWKEGDPVQV---VKNLHLPRFTLEKFLTDYCNSKTNTGEYSCLKVDLLFKREFSYYLIQIY 252
            :.::|.....:.|   .....|.::.|..........|::||||:.:......||:..|::||.|
Zfish   194 VTYVWTRNATLSVEVAPDGSRLNQYDLMGQTVGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTY 258

  Fly   253 IPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTF 317
            :||.|.||:|.|||||::.:||||...||||:|||.|.:.....|||.|:|..|:|.:..||..|
Zfish   259 LPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAF 323

  Fly   318 VFGALLEFALVNYASRSGSNKANMHKENMKKKRRDLEQASLDAASDLLDTDSNATFAMA-SQFAR 381
            ||.||:|||.|||.::.|.........|.|||...:.:             .|..:|:| :.:|
Zfish   324 VFSALIEFATVNYFTKRGWAWDGKSIVNDKKKETSVMK-------------KNNAYAVAVANYA- 374

  Fly   382 GGGQQKPLVRHPGDPLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRSKRIDVISRITFPLVFAL 446
                  |.:........:.|....|.....|......||:.|     ..:||.:|||.||::|..
Zfish   375 ------PHIAKDSALPTVSKSATPEPSKAQPVAKETKKTFNS-----VSKIDRMSRIIFPVLFGS 428

  Fly   447 FNLVYWSTYLFRE 459
            ||||||:|||.||
Zfish   429 FNLVYWATYLNRE 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluClalpha	NP_001287408.1	LIC	3..455	CDD:273305	160/462 (35%)
gabra2a	XP_009305482.1	LIC	17..437	CDD:273305	158/459 (34%)
		Neur_chan_LBD	43..250	CDD:280998	75/219 (34%)
		Neur_chan_memb	257..434	CDD:280999	72/201 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910