Protein Alignment Naam and Isoc1

DIOPT Version :10

• Sequence 1: NP_732446.1
• Gene: Naam / 42348
• FlyBaseID: FBgn0051216
• Length: 357
• Species: Drosophila melanogaster
• Sequence 2: NP_001014264.2
• Gene: Isoc1 / 364879
• RGDID: 1307632
• Length: 297
• Species: Rattus norvegicus
• Alignment Length: 362
• Identity: 65/362 - (17%)
• Similarity: 116/362 - (32%)
• Gaps: 132/362 - (36%)

  Fly    13 SNGSAMDACFTAFDKDSDDRLSL---AEFSIICRALFRNDKGHIYDVPPERLEQIFAVFDTNGDG 74
            |.|..:..||:.|.:.:    |:   |.:.::.:. |.:..|...|:..:.:.|:||
  Rat    22 SGGVPVLFCFSVFARPA----SVPHGAGYDVLIQK-FLSLYGDQLDMHRKFVVQLFA-------- 73

  Fly    75 FIDREEFKFCWNQWIKTIVRPVNAFLIVDVQNDFISGSLDISNCSAQQQGHEILEPINKLLDTVD 139
                ||    |.|::                 |...|......|..:      |.|:...|.|:.
  Rat    74 ----EE----WGQYV-----------------DLPKGFAVSERCKLR------LVPLQIQLTTLG 107

  Fly   140 F----DAVFYSLDWHPSDHVSFIDNVKMRPMDESSALDSDSAKVFDTVIFAGPPPMKQRLWPRH- 199
            .    ..||:..|...          :.||          :.|.|..:|..|     |||....
  Rat   108 NLTPPSTVFFCCDMQE----------RFRP----------AIKYFGDIISVG-----QRLLQGAR 147

  Fly   200 ------CVQDSWGAELHKDLKVVD-HGIKV------YKGTNPEVDSYSVFWDNKKLSDTTLNAQL 251
                  .:.:.:...|...::.:| .|:|:      :....|||::                |..
  Rat   148 ILGIPVIITEQYPKGLGSTVQEIDLTGVKLVLPKTKFSMVLPEVEA----------------ALA 196

  Fly   252 KMKGATDIYVCGLAYDVCVGATAVDALSAGYRTILIDDCCRGTDVHDIEHTKEK-------VNTS 309
            ::.|...:.:.|:...||:..||::.:..|....::.|......:.|.....|:       |.||
  Rat   197 EIPGVRSVVLFGVETHVCIQQTALELVGRGIEVHIVADATSSRSMMDRMFALERLARTGIIVTTS 261

  Fly   310 DGVIVH-------------TNQVKAMAEGRDRRPELG 333
            :.|::.             .|.:||.|      ||.|
  Rat   262 EAVLLQLVADKDHPKFKEIQNLIKASA------PESG 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Naam	NP_732446.1	FRQ1	<11..82	CDD:444056	15/71 (21%)
		nicotinamidase	97..315	CDD:238493	41/242 (17%)
Isoc1	NP_001014264.2	YcaC_related	115..269	CDD:238494	34/194 (18%)