Protein Alignment CG7432 and PRSS3

DIOPT Version :10

• Sequence 1: NP_650825.2
• Gene: CG7432 / 42347
• FlyBaseID: FBgn0038727
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001184026.3
• Gene: PRSS3 / 5646
• HGNCID: 9486
• Length: 261
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 89/299 - (29%)
• Similarity: 134/299 - (44%)
• Gaps: 49/299 - (16%)

  Fly   421 RPTSGLVLIPQKKPPTTTTTTTTEVPLEPEGLDEIGNNIVDPDECGQQEYSTGRIVGGVEAPNGQ 485
            |.|||..|...:..|.        |...|:.|..:.   .|.|:         :||||.......
Human     4 RETSGFTLKKGRSAPL--------VFHPPDALIAVP---FDDDD---------KIVGGYTCEENS 48

  Fly   486 WPWMAAIFLHGPKRTEFWCGGSLIGTKYILTAAHCTRDSRQKPFAARQFTVRLGDIDLSTDAEPS 550
            .|:..::     .....:||||||..:::::||||.:...|         ||||:.::.. .|.:
Human    49 LPYQVSL-----NSGSHFCGGSLISEQWVVSAAHCYKTRIQ---------VRLGEHNIKV-LEGN 98

  Fly   551 DPVTFAVKEVRTHERFSRIGFYNDIAILVLDKPVRKSKYVIPVCLPKGIRMPPKERLPGRRATVV 615
            :....|.|.:| |.:::|....|||.::.|..|...:..|..:.||   ..||   ..|....:.
Human    99 EQFINAAKIIR-HPKYNRDTLDNDIMLIKLSSPAVINARVSTISLP---TTPP---AAGTECLIS 156

  Fly   616 GWGTTY-YGGKESTSQRQAELPIWRNEDCDRSYFQPINENFICAGYSDGGVDACQGDSGGPLMMR 679
            |||.|. :|.......:..:.|:....:|..||...|..:..|.|:.:||.|:||.|||||::..
Human   157 GWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDSGGPVVCN 221

  Fly   680 YDSHWVQL-GVVSFGNKCGEPGYPGVYTRVTEYLDWIRD 717
                 .|| ||||:|:.|.....|||||:|..|:|||:|
Human   222 -----GQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKD 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7432	NP_650825.2	CLIP	335..378	CDD:197829
		Tryp_SPc	475..718	CDD:238113	78/245 (32%)
PRSS3	NP_001184026.3	Tryp_SPc	38..256	CDD:238113	78/245 (32%)