DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7432 and PLAT

DIOPT Version :9

Sequence 1:NP_650825.2 Gene:CG7432 / 42347 FlyBaseID:FBgn0038727 Length:721 Species:Drosophila melanogaster
Sequence 2:NP_000921.1 Gene:PLAT / 5327 HGNCID:9051 Length:562 Species:Homo sapiens


Alignment Length:278 Identity:98/278 - (35%)
Similarity:139/278 - (50%) Gaps:37/278 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   465 CGQQEYSTG--RIVGGVEAPNGQWPWMAAIFL-HGPKRTE-FWCGGSLIGTKYILTAAHCTRDSR 525
            ||.::||..  ||.||:.|.....||.||||. |.....| |.|||.||.:.:||:||||.    
Human   299 CGLRQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCF---- 359

  Fly   526 QKPFAARQFTVRLGDIDLSTDAEPSDPVTFAVKEVRTHERFSRIGFYNDIAILVL----DKPVRK 586
            |:.|.....||.||........|  :...|.|::...|:.|....:.||||:|.|    .:..::
Human   360 QERFPPHHLTVILGRTYRVVPGE--EEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQE 422

  Fly   587 SKYVIPVCLPKGIRMPPKERLPG-RRATVVGWG-----TTYYGGKESTSQRQAELPIWRNEDCDR 645
            |..|..||||     |...:||. ....:.|:|     :.:|    |...::|.:.::.:..|..
Human   423 SSVVRTVCLP-----PADLQLPDWTECELSGYGKHEALSPFY----SERLKEAHVRLYPSSRCTS 478

  Fly   646 SYF--QPINENFICAGYSDGG------VDACQGDSGGPLMMRYDSHWVQLGVVSFGNKCGEPGYP 702
            .:.  :.:.:|.:|||.:..|      .|||||||||||:...|.....:|::|:|..||:...|
Human   479 QHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVP 543

  Fly   703 GVYTRVTEYLDWIRDHTR 720
            ||||:||.|||||||:.|
Human   544 GVYTKVTNYLDWIRDNMR 561

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7432NP_650825.2 CLIP 335..378 CDD:197829
Tryp_SPc 474..715 CDD:214473 89/260 (34%)
Tryp_SPc 475..718 CDD:238113 91/262 (35%)
PLATNP_000921.1 FN1 41..83 CDD:214494
Important for binding to annexin A2 42..52
KR 125..209 CDD:238056
Kringle 215..296 CDD:306546
Tryp_SPc 313..559 CDD:238113 90/260 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 141 1.000 Inparanoid score I4483
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.960

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