Protein Alignment CG7432 and PLAT

DIOPT Version :10

• Sequence 1: NP_650825.2
• Gene: CG7432 / 42347
• FlyBaseID: FBgn0038727
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_000921.1
• Gene: PLAT / 5327
• HGNCID: 9051
• Length: 562
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 98/278 - (35%)
• Similarity: 139/278 - (50%)
• Gaps: 37/278 - (13%)

  Fly   465 CGQQEYSTG--RIVGGVEAPNGQWPWMAAIFL-HGPKRTE-FWCGGSLIGTKYILTAAHCTRDSR 525
            ||.::||..  ||.||:.|.....||.||||. |.....| |.|||.||.:.:||:||||.
Human   299 CGLRQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCF---- 359

  Fly   526 QKPFAARQFTVRLGDIDLSTDAEPSDPVTFAVKEVRTHERFSRIGFYNDIAILVL----DKPVRK 586
            |:.|.....||.||........|  :...|.|::...|:.|....:.||||:|.|    .:..::
Human   360 QERFPPHHLTVILGRTYRVVPGE--EEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQE 422

  Fly   587 SKYVIPVCLPKGIRMPPKERLPG-RRATVVGWG-----TTYYGGKESTSQRQAELPIWRNEDCDR 645
            |..|..||||     |...:||. ....:.|:|     :.:|    |...::|.:.::.:..|..
Human   423 SSVVRTVCLP-----PADLQLPDWTECELSGYGKHEALSPFY----SERLKEAHVRLYPSSRCTS 478

  Fly   646 SYF--QPINENFICAGYSDGG------VDACQGDSGGPLMMRYDSHWVQLGVVSFGNKCGEPGYP 702
            .:.  :.:.:|.:|||.:..|      .|||||||||||:...|.....:|::|:|..||:...|
Human   479 QHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVP 543

  Fly   703 GVYTRVTEYLDWIRDHTR 720
            ||||:||.|||||||:.|
Human   544 GVYTKVTNYLDWIRDNMR 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7432	NP_650825.2	CLIP	335..378	CDD:197829
		Tryp_SPc	475..718	CDD:238113	91/262 (35%)
PLAT	NP_000921.1	FN1	41..83	CDD:214494
		Important for binding to annexin A2	42..52
		EGF	86..117	CDD:394967
		KR	125..209	CDD:238056
		Kringle	215..296	CDD:395005
		Tryp_SPc	313..559	CDD:238113	90/260 (35%)