Protein Alignment CG7432 and Corin

DIOPT Version :10

• Sequence 1: NP_650825.2
• Gene: CG7432 / 42347
• FlyBaseID: FBgn0038727
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_610297.2
• Gene: Corin / 35691
• FlyBaseID: FBgn0033192
• Length: 1397
• Species: Drosophila melanogaster
• Alignment Length: 1009
• Identity: 225/1009 - (22%)
• Similarity: 336/1009 - (33%)
• Gaps: 371/1009 - (36%)

  Fly    22 PTAQGQSDAGNDEEQPLHLTNDASFFQPHLHDRRLGRQLIEDLAESQSSASSVSSGSS--QSGS- 83
            |..:|.|::.|.    :..|...|..:|            ..::.|.|::|:.|:|||  .||:
  Fly   405 PPVKGSSNSSNS----IGETQSQSSKEP------------SSVSASASTSSAASAGSSTISSGTM 453

  Fly    84 --------AYEDDDDDV---EGSSE-------YYDSDEEQSE-------------GSNE----SL 113
                    |.....|.:   .|..|       .:|..|..|.             |.|:    :.
  Fly   454 SSMSGPCPAVVPPTDAITKRPGPPEPPLRQANVFDPVETGSRGHPPPPLTVRNKLGRNKPPPITY 518

  Fly   114 PRLLSQ--STFNRISETLGALNHVGHMLVDITRGGQDQAKMEGAEKSEDTSQDNSQS-------- 168
            ||:..:  ||.:..|.::.:.......|::....|..|    |..||........|:
  Fly   519 PRMQQRQDSTLSSDSYSISSSPGYNSKLMEAPLLGSQQ----GGRKSNAPGSAQRQTPLMDLAPT 579

  Fly   169 ---GGSSSATASASSTTEVVP----------SSTSSPRGNSEQLPGVSDKLMD-PLPITLSANSL 219
               ||:...|.|......:.|          |:.||...:....||.:.|||: ||..:|||..|
  Fly   580 RFLGGAGGGTGSGKQGPAMPPPRSKINFRQDSTISSDSFSQTSSPGYNPKLMEAPLLPSLSAKRL 644

  Fly   220 L-------------------------------PAGKPANLSVI---------------QVATKRI 238
            .                               .||:|::|..|               |:..:|
  Fly   645 CSAPAPIVCRQGVQHEPIEELEPPQTISPLHKAAGQPSSLQTIVRFQNGAPHTMSLQHQIINRR- 708

  Fly   239 GMDDSAPMFVENKELK-----------------------------LKKKKKKNKNKQKVKKPSEE 274
               .|:..::.|..||                             :|...|...|...|:..:..
  Fly   709 ---KSSNPYITNGRLKFRLFQILINAFALLAIAGGLAAYFNAYPTIKFVNKTIINTIHVEDTTSF 770

  Fly   275 G----------VLVPVAQGAQ------------------QSQQKIK------------------- 292
            |          ::|...||.|                  ::|..:.
  Fly   771 GKNPAPGTCLPIIVRFCQGPQIPYNYTVFPNYIGHFGQLETQTDLDSYEALVDVRCYELVSLFLC 835

  Fly   293 ---IP-------TTPRTTTTSTTT-------------------------EAPIT----------- 311
               :|       |.|...|..|.|                         :.|.:
  Fly   836 TLFVPKCGQSGATVPPCKTLCTETMRRCGFFFDVFGLSLPEYLNCKLFKDFPSSEDCVGLDEVRE 900

  Fly   312 ------------------------------LTPLDQLAEASDEAGTGKDVENYCKTPS--GRRGR 344
                                          |..:||..||..|. .|.| |.||....  |.:..
  Fly   901 VMRAATHPKCDGFQCDQNRCLPQEYVCDGHLDCMDQADEAKCER-CGPD-EIYCGDSQCIGTKHI 963

  Fly   345 CEDLSSCPALLLNLSSLRES-----------------------LCFKS---LYVPGVCCPISSSS 383
            |:.:..||......:.||.|                       .|.|:   ...|...|.|...|
  Fly   964 CDGIIDCPYGQDERNCLRLSERNGDVGTGVLEVYRIGQRQWMPACVKNWDRAVSPSAVCSILGYS 1028

  Fly   384 TVLTTQKPLRLTTRPTTTTSTTKATQPTKKSTVRPTTRPTSGLVLIPQ----KKPPTTTTTTTTE 444
            .|..|....:||.||...| ...:|...|....|.:|       |:.:    ||        |.:
  Fly  1029 AVNATSVLTQLTHRPLLAT-VNVSTDIWKMYAKRKST-------LMQEFANCKK--------TED 1077

  Fly   445 VPLEPEGLDEIGNNIVDPDECGQ----QEYSTGRIVGGVEAPNGQWPWMAAIFLHGPKRTEFWCG 505
            .|:    .|...:|.    |||:    :...:.||:||.:|..|.||::||| |.||::. |:|.
  Fly  1078 YPM----ADLTCSNY----ECGRVKRGRHKPSRRIIGGTQASPGNWPFLAAI-LGGPEKI-FYCA 1132

  Fly   506 GSLIGTKYILTAAHCTRDSRQKPFAARQFTVRLGDIDLSTDAEPSDPVTFAVKEVRTHERFS-RI 569
            |.||..:::|||:||.  ..........:|::||....::.......|  .||.|..|.::: .|
  Fly  1133 GVLISDQWVLTASHCV--GNYSVIDLEDWTIQLGVTRRNSFTYSGQKV--KVKAVIPHPQYNMAI 1193

  Fly   570 GFYNDIAILVLDKPVRKSKYVIPVCLPKGIRMPPKER--LPGRRATVVGWGTTYYGGKESTSQ-- 630
            ...||||:..|...|...::::|||||     ||..|  .||...||:|||.......:||.:
  Fly  1194 AHDNDIALFQLATRVAFHEHLLPVCLP-----PPSVRNLHPGTLCTVIGWGKREDKDPKSTYEYI 1253

  Fly   631 -RQAELPIWRNEDCDRSYFQ-PINENFICAGYSDGGVDACQGDSGGPLMMRY---DSHWVQLGVV 690
             .:.::||.....||..... .::|..:|||:.|||.|||||||||||:..|   .:.|...|:|
  Fly  1254 VNEVQVPIITRNQCDEWLDNLTVSEGMVCAGFDDGGKDACQGDSGGPLLCPYPGEKNRWFVGGIV 1318

  Fly   691 SFGNKCGEPGYPGVYTRVTEYLDWIRD----HTR 720
            |:|..|..|..||||..|.:|:.||::    |:|
  Fly  1319 SWGIMCAHPRLPGVYANVVQYVPWIQEQIAKHSR 1352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7432	NP_650825.2	CLIP	335..378	CDD:197829	11/70 (16%)
		Tryp_SPc	475..718	CDD:238113	93/256 (36%)
Corin	NP_610297.2	CRD_FZ	778..894	CDD:143549	12/115 (10%)
		LDLa	911..942	CDD:238060	5/30 (17%)
		LDLa	945..979	CDD:238060	9/34 (26%)
		SR	980..>1034	CDD:214555	10/53 (19%)
		Tryp_SPc	1104..1346	CDD:238113	93/252 (37%)