DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7432 and F2

DIOPT Version :9

Sequence 1:	NP_650825.2	Gene:	CG7432 / 42347	FlyBaseID:	FBgn0038727	Length:	721	Species:	Drosophila melanogaster
Sequence 2:	NP_075213.2	Gene:	F2 / 29251	RGDID:	61996	Length:	617	Species:	Rattus norvegicus

Alignment Length:	310	Identity:	99/310 - (31%)
Similarity:	137/310 - (44%)	Gaps:	50/310 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   425 GLVLIPQKKPPTTTTTTTTEVPLEPEGLDEIGNNIVDPDECGQQEYSTGRIVGGVEAPNGQWPWM 489
            ||..:.:||..|..|        |.|.||               .|..||||.|.:|..|..||.
  Rat   333 GLRPLFEKKSLTDKT--------EKELLD---------------SYIDGRIVEGWDAEKGIAPWQ 374

  Fly   490 AAIFLHGPKRTEFWCGGSLIGTKYILTAAHC-TRDSRQKPFAARQFTVRLGDIDLSTDAEPSDPV 553
            ..:|...|:  |..||.|||..:::|||||| ......|.|......||:|....:......:.:
  Rat   375 VMLFRKSPQ--ELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLLVRIGKHSRTRYERNVEKI 437

  Fly   554 TFAVKEVRTHERFS-RIGFYNDIAILVLDKPVRKSKYVIPVCLPKGIRMPPKERL-----PGRRA 612
            :. ::::..|.|:: |.....|||:|.|.|||..|.|:.||||      |.|:.:     .|.:.
  Rat   438 SM-LEKIYIHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCL------PDKQTVTSLLQAGYKG 495

  Fly   613 TVVGWG------TTYYGGKESTSQRQAELPIWRNEDCDRSYFQPINENFICAGYSDGGV---DAC 668
            .|.|||      ||.....:.:..:...|||.....|..|....|.:|..|||:.....   |||
  Rat   496 RVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRIRITDNMFCAGFKVNDTKRGDAC 560

  Fly   669 QGDSGGPLMMR--YDSHWVQLGVVSFGNKCGEPGYPGVYTRVTEYLDWIR 716
            :||||||.:|:  |:..|.|:|:||:|..|...|..|.||.|.....|::
  Rat   561 EGDSGGPFVMKSPYNHRWYQMGIVSWGEGCDRNGKYGFYTHVFRLKRWMQ 610

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7432	NP_650825.2	CLIP	335..378	CDD:197829
		Tryp_SPc	474..715	CDD:214473	86/258 (33%)
		Tryp_SPc	475..718	CDD:238113	86/260 (33%)
F2	NP_075213.2	GLA	25..89	CDD:214503
		KR	107..189	CDD:214527
		Kringle	215..292	CDD:278480
		Thrombin_light	312..359	CDD:286482	11/48 (23%)
		Tryp_SPc	359..608	CDD:214473	86/257 (33%)
		Tryp_SPc	360..612	CDD:238113	86/260 (33%)
		High affinity receptor-binding region which is also known as the TP508 peptide	547..569		11/21 (52%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	142	1.000	Inparanoid score	I4384
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.960