DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7432 and Mst1

DIOPT Version :9

Sequence 1:	NP_650825.2	Gene:	CG7432 / 42347	FlyBaseID:	FBgn0038727	Length:	721	Species:	Drosophila melanogaster
Sequence 2:	XP_038936729.1	Gene:	Mst1 / 24566	RGDID:	3114	Length:	747	Species:	Rattus norvegicus

Alignment Length:	504	Identity:	124/504 - (24%)
Similarity:	208/504 - (41%)	Gaps:	100/504 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   262 NKNKQKVKKPSEEGVLVPVAQGAQQSQQKIKIPTTP---------RTTTTSTTTEAPITLTPLDQ 317
            |..|...:..:..|..:|......:|||:.|:..:.         |.||.:|:...|.      |
  Rat   287 NLEKTGRRGSTRRGPNLPPTTKGSKSQQRNKVKASNCFRGKGEDYRGTTNTTSAGVPC------Q 345

  Fly   318 LAEASD--------EAGTGKDV-ENYCKTPSGRRGRCEDLSSCPALLLNLSSLRESLCFK----- 368
            ..:|.:        |....||: ||:|:.|.|        |..|....:...||.:.|::
  Rat   346 RWDAQNPHQHRFVPEKYACKDLRENFCRNPDG--------SEAPWCFTSRPGLRVAFCYQIPRCT 402

  Fly   369 SLYVPGVCCPISSS---STVLTTQKPLRLTTRPTTTTSTTKATQPTKKSTVRPTTRPTSGLVLIP 430
            ...||..|...|..   .:|..|:|.::.....:.|....:.|         ||:.|.:||....
  Rat   403 EEVVPEGCYHGSGEQYRGSVSKTRKGVQCQHWSSETPHKPQFT---------PTSAPHAGLEANF 458

  Fly   431 QKKP------PTTTTTTTTEVPLEPEGL----------DEIGNNIVDP------DECGQQ--EYS 471
            .:.|      |...|       |:||.|          |:...:|:||      ::||::  :.:
  Rat   459 CRNPDGDSHGPWCYT-------LDPETLFDYCALKRCDDDQPPSILDPPVQVQFEKCGKRVDQSN 516

  Fly   472 TGRIVGGVEAPNGQWPWMAAIFLHGPKRTEFWCGGSLIGTKYILTAAHCTRDSRQKPFAARQFTV 536
            ..|:|||   ..|..||..::   ..::.:.:|||||:..:::|||..|.. |...|...  :.|
  Rat   517 RLRVVGG---HPGNSPWTVSL---RNRQGQHFCGGSLVKEQWVLTARQCIW-SCHDPLTG--YEV 572

  Fly   537 RLGDIDLSTDAEPSDPVTFAVKEVRTHERFSRIGFYNDIAILVLDKPVRKSKYVIPVCLPKGIRM 601
            .||.|  :.:.:|.:.....|...:|  .....|  :.:.:|.|::||..:.:|..:|||....:
  Rat   573 WLGTI--NQNPQPGEANLQRVSVAKT--VCGPAG--SQLVLLKLERPVILNHHVARICLPPEQYV 631

  Fly   602 PPKERLPGRRATVVGWGTTYYGGKESTSQRQAELPIWRNEDCDRSYFQPINENFICAGYSDGGVD 666
            .|    ||....:.|||.: .|...||....|::.:..:::|:..|.:.:.|:.||.........
  Rat   632 VP----PGTNCEIAGWGES-KGTSNSTVLHVAKMKVISSQECNVKYRRRVQESEICTEGLLAPTG 691

  Fly   667 ACQGDSGGPLMMRYDSHWVQLGVVSFGNKCGEPGYPGVYTRVTEYLDWI 715
            ||:||.||||.......||..|::.....|..|.:|.::|||:.::|||
  Rat   692 ACEGDYGGPLACYTHDCWVLQGLIIPNRVCARPRWPAIFTRVSVFVDWI 740

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7432	NP_650825.2	CLIP	335..378	CDD:197829	11/47 (23%)
		Tryp_SPc	474..715	CDD:214473	67/240 (28%)
		Tryp_SPc	475..718	CDD:238113	68/241 (28%)
Mst1	XP_038936729.1	PAN_1	32..111	CDD:394981
		KR	116..196	CDD:214527
		KR	199..276	CDD:214527
		KR	321..403	CDD:214527	20/95 (21%)
		KR	408..490	CDD:214527	19/97 (20%)
		Tryp_SPc	520..743	CDD:238113	68/241 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	142	1.000	Inparanoid score	I4384
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.050