DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7432 and clec-4

DIOPT Version :9

Sequence 1:	NP_650825.2	Gene:	CG7432 / 42347	FlyBaseID:	FBgn0038727	Length:	721	Species:	Drosophila melanogaster
Sequence 2:	NP_496688.1	Gene:	clec-4 / 189654	WormBaseID:	WBGene00012583	Length:	425	Species:	Caenorhabditis elegans

Alignment Length:	284	Identity:	53/284 - (18%)
Similarity:	87/284 - (30%)	Gaps:	106/284 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   490 AAIFLHGPKRTEFWCGGSLIGTKYILTAAHCTRDSRQ-KPFAAR--QFTVRLGDIDLSTDAEPSD 551
            |:.:..|.|..|..||.        |.:.|...::|. ..|..|  :..:.||.:      .|:|
Worm   177 ASTYTKGQKICEQECGN--------LASIHSANENRYIMTFGGRATKEDLLLGGM------WPAD 227

  Fly   552 PV-TFAVKEVRTHERFSRIGFYNDIAILVLD---KPVR---------KSKYVIPVCLPKGIRMPP 603
            .| .:....:..:|.|..|...:.:.:::.:   :|:.         |::|.:....|.||:.||
Worm   228 DVYNWVDGSLWEYENFDPINVRDSVCVIMSNGDSRPIALGMWYSGECKNEYSVVCKRPAGIQCPP 292

  Fly   604 KERLPGRRATVVGWGTTYYGGKESTSQRQAELPIWR----NEDCDRSYFQP------------IN 652
                   ..|:|                    |:..    ...|:.|...|            .|
Worm   293 -------NPTIV--------------------PVTPMPAVQSFCNSSVMAPSEITSPHFPYNYYN 330

  Fly   653 ENFICAGYSDGG-------------------VDACQGDS-GGPLMMRYDSHWVQLGVVSFGNKC- 696
            .:|.....|..|                   |....||| ..|::..|...:....|:|.|||.
Worm   331 SDFCSYQISTLGSYNVLLRFSTFDTEKVNDVVTVYDGDSTNDPVIGVYAGSFYPFTVISTGNKML 395

  Fly   697 ---------GEPGYPGVYTRVTEY 711
                     ...|:.|   |:|.|
Worm   396 VTFKTDKSNTRQGFSG---RITSY 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7432	NP_650825.2	CLIP	335..378	CDD:197829
		Tryp_SPc	474..715	CDD:214473	53/284 (19%)
		Tryp_SPc	475..718	CDD:238113	53/284 (19%)
clec-4	NP_496688.1	CLECT	27..153	CDD:214480
		CLECT	162..283	CDD:214480	22/119 (18%)
		CUB	309..415	CDD:238001	21/108 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6818
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950