DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7432 and Hgf

DIOPT Version :9

Sequence 1:	NP_650825.2	Gene:	CG7432 / 42347	FlyBaseID:	FBgn0038727	Length:	721	Species:	Drosophila melanogaster
Sequence 2:	NP_001276387.1	Gene:	Hgf / 15234	MGIID:	96079	Length:	728	Species:	Mus musculus

Alignment Length:	470	Identity:	104/470 - (22%)
Similarity:	151/470 - (32%)	Gaps:	181/470 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   329 KDV-ENYCKTPSG-------------RRGRCEDLSSCPA-------------LLLNLSSLRESL- 365
            ||: ||||:.|.|             |.|.|..:..|..             .:.|||..|..|
Mouse   348 KDLRENYCRNPDGAESPWCFTTDPNIRVGYCSQIPKCDVSSGQDCYRGNGKNYMGNLSKTRSGLT 412

  Fly   366 ----------------------------------------CFK-SLYVPGVCCPIS-----SSST 384
                                                    |:. :..:|...||||     ::.|
Mouse   413 CSMWDKNMEDLHRHIFWEPDASKLNKNYCRNPDDDAHGPWCYTGNPLIPWDYCPISRCEGDTTPT 477

  Fly   385 VLTTQKPLRLTTRPTTTTSTTKATQPTKKSTVRPTTRPTSGLVLIPQKKPPTTTTTTTTEVPLEP 449
            ::....|:         .|..|..|          .|..:|:        ||.||
Mouse   478 IVNLDHPV---------ISCAKTKQ----------LRVVNGI--------PTQTT---------- 505

  Fly   450 EGLDEIGNNIVDPDECGQQEYSTGRIVGGVEAPNGQWPWMAAIFLHGPKRTEFWCGGSLIGTKYI 514
                                      ||          ||.::    ..|.:..||||||...::
Mouse   506 --------------------------VG----------WMVSL----KYRNKHICGGSLIKESWV 530

  Fly   515 LTAAHCTRDSRQKPFAARQFTVRLGDIDLSTDAEPSDPVTFAVKEVRTHERFSRIGFY----NDI 575
            |||..|. .:|.|..  :.:...||..|:....|........:.::          .|    :|:
Mouse   531 LTARQCF-PARNKDL--KDYEAWLGIHDVHERGEEKRKQILNISQL----------VYGPEGSDL 582

  Fly   576 AILVLDKPVRKSKYVIPVCLPK-GIRMPPKERLPGRRATVVGWGTTYYGGKESTS--QRQAELPI 637
            .:|.|.:|.....:|..:.||. |..:|.|     ...::.|||   |.|..:..  .|.|.|.|
Mouse   583 VLLKLARPAILDNFVSTIDLPSYGCTIPEK-----TTCSIYGWG---YTGLINADGLLRVAHLYI 639

  Fly   638 WRNEDCDRSYFQPI--NENFICAGYSDGGVDACQGDSGGPLMMRYDSHWVQLGVVSFGNKCGEPG 700
            ..||.|.:.:...:  ||:.:|||....|...|:||.||||:.......:.|||:..|..|..|.
Mouse   640 MGNEKCSQHHQGKVTLNESELCAGAEKIGSGPCEGDYGGPLICEQHKMRMVLGVIVPGRGCAIPN 704

  Fly   701 YPGVYTRVTEYLDWI 715
            .||::.||..|..||
Mouse   705 RPGIFVRVAYYAKWI 719

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7432	NP_650825.2	CLIP	335..378	CDD:197829	14/110 (13%)
		Tryp_SPc	474..715	CDD:214473	68/249 (27%)
		Tryp_SPc	475..718	CDD:238113	70/250 (28%)
Hgf	NP_001276387.1	PAN_APPLE	41..123	CDD:238074
		KR	127..209	CDD:214527
		KR	211..289	CDD:214527
		KR	305..385	CDD:214527	11/36 (31%)
		KR	389..471	CDD:238056	11/81 (14%)
		Tryp_SPc	495..719	CDD:214473	74/302 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	141	1.000	Inparanoid score	I4469
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.050