DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6184 and FAM234B

DIOPT Version :10

Sequence 1:NP_732443.4 Gene:CG6184 / 42345 FlyBaseID:FBgn0038725 Length:1029 Species:Drosophila melanogaster
Sequence 2:NP_065904.1 Gene:FAM234B / 57613 HGNCID:29288 Length:622 Species:Homo sapiens


Alignment Length:578 Identity:129/578 - (22%)
Similarity:203/578 - (35%) Gaps:155/578 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   177 AGSSRISY----------GSS-----LGSEFVPCTQISVQKRWSRSLARMNSE--SPLRAADLNG 224
            |.||.:||          |.|     |.:..:||....:...|||.|......  |||..||:||
Human    94 AASSLVSYVRTSVFLLTLGISMILVLLCAFLIPCPPRDLHSTWSRHLGSQGGGDLSPLELADVNG 158

  Fly   225 DGIKDVVFGYGVDDNIPYEGIPLPRCQCAQQGEEVPCEGGVVALNGLDGSILWQSWSVANVFSLH 289
            ||::||:..:.:..|....|:..|             ...:|.|:|::||.||.|........:.
Human   159 DGLRDVLLSFVMSRNGSAVGVSRP-------------AANLVCLSGMNGSTLWSSLLPEEARDIT 210

  Fly   290 CSADVDGD-GGTDCVAAGRLGMIYAINGRTGSVIWSFRELEVETN---SPIVMDLYTINVLRDLD 350
            |...:.|. ..|.|:..|...|:.|.|..:|..||:.....:...   :|:|       ||.|||
Human   211 CLELMPGSLAETICLVTGTHKMLSAFNATSGKAIWTLNPNYLSNGTLAAPVV-------VLPDLD 268

  Fly   351 GDSVPEVIAAHLEEREESKAGHIKLISGKTGKVIRSIPTPYR----EEMFVPIQLITQADGTELL 411
            .|.|.:::...:.|.:....  ..|:||:||..: ..|..|.    ..:..| |:....:|...:
Human   269 EDGVRDLVVLAIGELQPDLC--FLLVSGRTGNPV-GRPVKYNIVGVGNLIGP-QVYITTNGAVYI 329

  Fly   412 LIVTGGQNTPGGIYSLRLHSLMAHTSEKHFTP---------LHRQQGSGLMVPAVLTDLNGDGI- 466
            |...      |.|.::.|..:......:..:|         ..:::...|   :.|.|:..||: 
Human   330 LFGF------GNIQAVALRDIFVQAQNRDSSPPSLQIEEPEWEKRRSINL---SELIDVYSDGVE 385

  Fly   467 ------------SDVVVAAFNRSVLAFDGANYTMMWNYTFPASECVSAIVPGLFNHDRVTDFMVK 519
                        |::::.. .:|::...|.|.|..|........  |...||.|..|:..||:::
Human   386 LLQMVKAPDSNCSNLLITT-RQSLVLLRGQNLTPYWALRLQGLR--SQPTPGYFTDDQTLDFLLQ 447

  Fly   520 YNTGPGFPVYYYSQTTILDGRNGQ--------------PLLNAMMTDAGGANSLLGGVSISQSFG 570
            ...|.|.     .:..::||.:|.              |..:|:.:|....              
Human   448 IQDGVGM-----KKMMVVDGDSGSIVWSYRAPCHMKETPATSAVTSDQKSV-------------- 493

  Fly   571 GDFFLHWQLQCRNRPDARDAYEFVPDSDIILQARADTCRLRY-----NESTMLKLYGIARHIEPP 630
               ||.|         |.......|:|||||.....:....|     ..|.:|.|      ....
Human   494 ---FLFW---------AEGLSAASPNSDIILGTEPPSLHHLYLLHPAFPSILLDL------ANTT 540

  Fly   631 GAVLFSTDDLEVQLN----------RTQRPAAAGKKSPLKHPKLLKK--LLAGNREQL 676
            |.|..|    ||.:|          ||..|::.|..:.|...||..:  |:.|...||
Human   541 GTVTAS----EVGINDLWKDAFYVTRTTGPSSEGHPAALVVSKLSLRWALMEGQMAQL 594

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6184NP_732443.4 PQQ <263..>328 CDD:441129 19/65 (29%)
FG-GAP_3 460..518 CDD:433275 16/70 (23%)
FAM234BNP_065904.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..68
Blue background indicates that the domain is not in the aligned region.

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