DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31219 and CG1299

DIOPT Version :9

Sequence 1:	NP_001097837.1	Gene:	CG31219 / 42344	FlyBaseID:	FBgn0051219	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster

Alignment Length:	369	Identity:	113/369 - (30%)
Similarity:	165/369 - (44%)	Gaps:	86/369 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 DCYPGEKYVYLYECPHVYTAGRSRTLMREYDMDAWLL------------FGQRICC--------- 67
            |..|| ..|.:.||..:....|||:      .||...            .|.::||
  Fly   168 DTKPG-NCVEIKECASLLNELRSRS------QDATFANFLRASNAVCQNKGTQVCCPTGQGITNT 225

  Fly    68 -PPPGNRLPST------------EICGQSLSTY-RMVGGSEARPNGYPWMAMLLYLNTTTLEILP 118
             |.|...:|..            |.||.::..: ::|||..:|...:||:|:|.|.:.:.   .|
  Fly   226 TPAPSQIVPKNTDEIPRRLLNVEEGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYDDPSG---SP 287

  Fly   119 F-CAGSLINNRYVLTSAHCVNGIPRDLSLKSVRLGEHDITYDPAYNPDCRDQDNQCALPNLEIKL 182
            | |.|:||..|:|||:|||:.   :||..  |||||||::.|....             :::|.:
  Fly   288 FKCGGTLITARHVLTAAHCIR---QDLQF--VRLGEHDLSTDTETG-------------HVDINI 334

  Fly   183 EKIIVHGLFSSISNRNIEYDIALLRLKMPVRYRTGIMPICIPKHGFFAKSKLE------IAGWGK 241
            .:.:.|   ...:.||...|:|:|.|:..|.:.:.|.|||:| |....:.|..      :|||||
  Fly   335 ARYVSH---PDYNRRNGRSDMAILYLERNVEFTSKIAPICLP-HTANLRQKSYVGYMPFVAGWGK 395

  Fly   242 TNE-GQFSQVLMHGFIRERSIAVCALRFP----YLDLNQ--SLQICAGGYD-GVDTCQGDSGGPL 298
            |.| |:.:|||....|......||...:.    |...:|  ...:|||... |.|||||||||||
  Fly   396 TMEGGESAQVLNELQIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGVLSGGKDTCQGDSGGPL 460

  Fly   299 MVT---MDNSSVYLAGITTYGSKNCGQIGIPGIYTRTSAFLPWI 339
            |:.   ......||.|:.:||. .|.:..:||:|:.|..|:.||
  Fly   461 MLPEPYQGQLRFYLIGVVSYGI-GCARPNVPGVYSSTQYFMDWI 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31219	NP_001097837.1	Tryp_SPc	88..339	CDD:214473	91/268 (34%)
CG31219	NP_001097837.1	Tryp_SPc	90..342	CDD:238113	93/268 (35%)
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	12/54 (22%)
		Tryp_SPc	260..503	CDD:214473	91/268 (34%)
		Tryp_SPc	261..503	CDD:238113	91/267 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.010