DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31219 and F10

DIOPT Version :9

Sequence 1:	NP_001097837.1	Gene:	CG31219 / 42344	FlyBaseID:	FBgn0051219	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_058839.1	Gene:	F10 / 29243	RGDID:	61850	Length:	482	Species:	Rattus norvegicus

Alignment Length:	319	Identity:	96/319 - (30%)
Similarity:	148/319 - (46%)	Gaps:	82/319 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 PPPGNRLPSTEIC------------------GQSLSTYRMVGGSEARPNGYPWMAMLLYLNTTTL 114
            |.|.:.:|..:|.                  ..|....|:|||.|.:....||.|:|.    :..
  Rat   193 PDPEDLMPDADILYPTESPSELLNLNKTEPEANSDDVIRIVGGQECKRGECPWQALLF----SDE 253

  Fly   115 EILPFCAGSLINNRYVLTSAHCVNGIPRDLSLKSVRLGEHDITYDPAYNPDCRDQDNQCALPNLE 179
            |...||.|:::|..|:||:|||::...|    ..||:|:        .|.:..|..      .:.
  Rat   254 ETDGFCGGTILNEFYILTAAHCLHQAKR----FKVRVGD--------LNTEQEDGG------EMV 300

  Fly   180 IKLEKIIVHGLFSSISNRNIEYDIALLRLKMPVRYRTGIMPICIPKHGFFAKSKLE------IAG 238
            .:::.||.|..|   .....::|||:||||.|:.:|..:.|.|:|:.. :|::.|.      ::|
  Rat   301 HEVDMIIKHNKF---QRDTYDFDIAMLRLKTPITFRENVAPACLPQKD-WAEATLMTQKTGIVSG 361

  Fly   239 WGKTNE-GQFSQVLMHGFIRERSIAVCALRFPYLD-----LNQSLQI-----CAGGYDG--VDTC 290
            :|:|:| |:.|:||.            .:..||:|     |:.|..|     || |||.  .|.|
  Rat   362 FGRTHEKGRQSKVLK------------MMEVPYVDRNTCRLSTSFSITQNMFCA-GYDAKQEDAC 413

  Fly   291 QGDSGGPLMVTMDNSSVYLAGITTYGSKNCGQIGIPGIYTRTSAFLPWI----KAVLRP 345
            ||||||| .||....:.::.||.::| :.|.:.|..||||:.:|||.||    ||.:.|
  Rat   414 QGDSGGP-HVTRFKDTYFVTGIVSWG-EGCARKGKYGIYTKVTAFLKWIDRSMKARVGP 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31219	NP_001097837.1	Tryp_SPc	88..339	CDD:214473	86/269 (32%)
CG31219	NP_001097837.1	Tryp_SPc	90..342	CDD:238113	88/274 (32%)
F10	NP_058839.1	GLA	23..84	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:405372
		Tryp_SPc	232..462	CDD:238113	87/270 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010