Protein Alignment CG6195 and DRG1

DIOPT Version :10

• Sequence 1: NP_650822.1
• Gene: CG6195 / 42343
• FlyBaseID: FBgn0038723
• Length: 363
• Species: Drosophila melanogaster
• Sequence 2: NP_004138.1
• Gene: DRG1 / 4733
• HGNCID: 3029
• Length: 367
• Species: Homo sapiens
• Alignment Length: 363
• Identity: 205/363 - (56%)
• Similarity: 265/363 - (73%)
• Gaps: 3/363 - (0%)

  Fly     4 LEKIAEIEREIARTQKNKATEYHLGLLKAKLAKYRSQLLEP--SKKGEKGDGFDVLKSGDARVAL 66
            |.||||||.|:|||||||||.:|||||||:|||.|.:|:.|  ...|..|:||||.|:||||:..
Human     5 LAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGGGPGEGFDVAKTGDARIGF 69

  Fly    67 IGFPSVGKSTMLSTLTKTESEAANYEFTTLTCIPGVIEYQGANIQLLDLPGIIEGAAQGKGRGRQ 131
            :|||||||||:||.|....||.|.|||||||.:||||.|:||.|||||||||||||..|||||||
Human    70 VGFPSVGKSTLLSNLAGVYSEVAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDGKGRGRQ 134

  Fly   132 VIAVARTADLVLMMLDATKPNVHRELLERELESVGIRLNKRKPNIYFKQKKGGGLSFNATCSLTR 196
            |||||||.:|:|::||..||..|::::|.|||..|||||.:.|||.||:|..||::..|||..:.
Human   135 VIAVARTCNLILIVLDVLKPLGHKKIIENELEGFGIRLNSKPPNIGFKKKDKGGINLTATCPQSE 199

  Fly   197 CNEKMVQTILHSFKIFNAEVLFREDCTEDEFIDVVTANRVYLPCLYVYNKIDQISIEEVDRLARQ 261
            .:.:.|::||..:||.||:|..|.|.|.|:.||||..||||:||:||.||||||||||:|.:.:.
Human   200 LDAETVKSILAEYKIHNADVTLRSDATADDLIDVVEGNRVYIPCIYVLNKIDQISIEELDIIYKV 264

  Fly   262 PNSIVVSCNMKLNLDYMMEALWEALQLIRVYTKKPGAPPDFDDGLIL-RKGVSVEHVCHAIHRTL 325
            |:.:.:|.:.:.|.|.::|.:|:.|:|:|:|||..|..||:...::| ....:||..|..||:.|
Human   265 PHCVPISAHHRWNFDDLLEKIWDYLKLVRIYTKPKGQLPDYTSPVVLPYSRTTVEDFCMKIHKNL 329

  Fly   326 AAQFKYALVWGTSTKYSPQRVGIAHVMADEDVIQVVKK 363
            ..:||||||||.|.|::||:||..|.:.||||||:|||
Human   330 IKEFKYALVWGLSVKHNPQKVGKDHTLEDEDVIQIVKK 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6195	NP_650822.1	Rbg1	1..363	CDD:440777	203/361 (56%)
DRG1	NP_004138.1	Required for interaction with STK16. /evidence=ECO:0000269|PubMed:18184589	2..16		8/10 (80%)
		Rbg1	7..367	CDD:440777	202/359 (56%)