Protein Alignment Nup58 and NUP42

DIOPT Version :10

• Sequence 1: NP_650821.2
• Gene: Nup58 / 42342
• FlyBaseID: FBgn0038722
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: NP_010478.3
• Gene: NUP42 / 851774
• SGDID: S000002600
• Length: 430
• Species: Saccharomyces cerevisiae
• Alignment Length: 455
• Identity: 135/455 - (29%)
• Similarity: 179/455 - (39%)
• Gaps: 137/455 - (30%)

  Fly     4 PTTNNAIGGATAATGAFAFGARPATTTAPPPSFGAATSTPTFGAAPATTSLFAAPAATPAFGAPA 68
            |.||||  .:|...|..|||.         ||||.| :|.|.|    ||        |.|||
Yeast    24 PFTNNA--ASTNNMGGSAFGR---------PSFGTA-NTMTGG----TT--------TSAFG--- 61

  Fly    69 ATPAFGAPASTPG------FGATSTA-------APAFGTAA---ATPAFGIPAATSAFGAPA-AT 116
             .|.||......|      ||.||.|       |||||::|   ..|    |:.|||||||: .:
Yeast    62 -MPQFGTNTGNTGNTSISAFGNTSNAAKPSAFGAPAFGSSAPINVNP----PSTTSAFGAPSFGS 121

  Fly   117 PAFGAAAATP--------AFGAPAATPAFGA-----PAAT------SAFGA----PAATTA-FGA 157
            ..|||.|||.        :.|:....|||||     |:::      |||||    |..||: ||:
Yeast   122 TGFGAMAATSNPFGKSPGSMGSAFGQPAFGANKTAIPSSSVSNSNNSAFGAASNTPLTTTSPFGS 186

  Fly   158 -------PASTQASAFGAP--APAVGTVAPTFSFATPATSAPTTAPPAFGFGTTATTAAAAMP-A 212
                   .||:.:||||.|  ..|..|.:|..:....:||:.|...|   |||..|.:....| :
Yeast   187 LQQNASQNASSTSSAFGKPTFGAATNTQSPFGTIQNTSTSSGTGVSP---FGTFGTNSNNKSPFS 248

  Fly   213 SLSSGIGSFSFPKPQATTAASLNFNTTTTTATAQPFNTGLK-LGTTNATTTL--GGGGIFSKPAG 274
            :|.||.|:.|.|           |.|||:.|.... |.|.. .||||..:..  |.||.|...:.
Yeast   249 NLQSGAGAGSSP-----------FGTTTSKANNNN-NVGSSAFGTTNNQSPFSGGSGGTFGSASN 301

  Fly   275 ---QAAAPAASTFVGLG---GI-------DVTATQPKLGD---NKQDGIKIKETQVPDEIIKTVD 323
               .......|:|...|   ||       .|:.:.|..|.   |....|.:|........
Yeast   302 LNKNTNGNFQSSFGNKGFSFGITPQNDANKVSQSNPSFGQTMPNTDPNISLKSNGNATSF----- 361

  Fly   324 GLKAYIKQQKTISSDIGRTSTSKFTNVSHEITNLKWALQNMATLVEGSNQQIRLMRQETVKAIQS 388
               .:.:||...::....|:|.|...| ..:::.|..:..:|.|.|           ||:|..::
Yeast   362 ---GFGQQQMNATNVNANTATGKIRFV-QGLSSEKDGILELADLAE-----------ETLKIFRA 411

  Fly   389  388
            Yeast   412  411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nup58	NP_650821.2	PHA03247	<25..195	CDD:223021	74/219 (34%)
		Nucleoporin_FG2	136..>525	CDD:435043	79/298 (27%)
NUP42	NP_010478.3	FhaB	<2..>380	CDD:442443	125/410 (30%)