DRSC/TRiP Functional Genomics Resources

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Protein Alignment Nup58 and Nup62

DIOPT Version :9

Sequence 1:NP_650821.2 Gene:Nup58 / 42342 FlyBaseID:FBgn0038722 Length:546 Species:Drosophila melanogaster
Sequence 2:NP_001286489.1 Gene:Nup62 / 36830 FlyBaseID:FBgn0034118 Length:394 Species:Drosophila melanogaster


Alignment Length:417 Identity:111/417 - (26%)
Similarity:159/417 - (38%) Gaps:123/417 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    26 PATTTAPPPSFGAATSTPTFGAAPATTSLFAAPAATPAFGAPAATPA------FGAPASTPGFG- 83
            |.||.||.   |.|||:.:||.:..|      |||.||.||....||      ||.||.|.|.| 
  Fly     6 PTTTAAPT---GGATSSFSFGLSTGT------PAAAPASGAATTAPATKTTFSFGTPAPTAGIGG 61

  Fly    84 -----ATSTAAPAF------GTAAATPAFGIPAATSAFGAPAATPAFGAAAATPAFGAPAATPAF 137
                 :.:.|.|||      |||:|....|..||.:.....:|| |.|.:||.||||...|.|| 
  Fly    62 GDADNSKAQAPPAFGFGLGSGTASAPLTLGTQAAANPASTTSAT-ATGTSAAPPAFGGFTAQPA- 124

  Fly   138 GAPAATSAFGAPAATTAFGAPASTQASAFGAPAPAVGTVAPTFSFATPATSAPTTA-PPAFGFGT 201
                                                .:|.||.:.:.|.|:|.||. ....|.|.
  Fly   125 ------------------------------------ASVVPTIATSAPNTAATTTGLLGGSGLGA 153

  Fly   202 TATTAAA-----AMPASLSSGIGSFSFPKPQATT-AASLNFNTTTTTATAQPFNTGLKLGTTNAT 260
            ..|||||     |.|::::|..|  :.|.|..:| .|..|..|.|.|..:...:|..:|......
  Fly   154 PKTTAAASTTLTAAPSAIASTQG--AAPAPTLSTGGAFANLTTETKTTDSSAVSTASQLSYHQLE 216

  Fly   261 TTLG--------GGGIFSKPAGQAAAPAASTFVGLGGIDVTATQPKLGDNK------QDGIKIKE 311
            ..:.        ...:|::.|.|                :.|....|..|.      .|.:|..:
  Fly   217 EHINKWTLEFEEQEKVFTEQATQ----------------INAWDKLLISNNGKIVELNDAVKKVK 265

  Fly   312 T--QVPDEIIKTVDGLKAYIKQQKTISSDIGRTSTSKFTNVSHEITNL-KWALQNMAT--LVEGS 371
            |  ||.|:.::.:      ..|||.:...:|        .:..|..|| :..::...|  :||..
  Fly   266 TDQQVLDQELEFI------ATQQKELEDSLG--------PLEKEFVNLPRVDMERSQTYLMVENL 316

  Fly   372 NQQIRLMRQETVKAIQSLEMAQRTQDT 398
            :.|::.|.::..:.|.:|..|.:.|||
  Fly   317 DTQLKQMSEDLKEIIDNLNEANKGQDT 343

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Nup58NP_650821.2 PHA03247 <25..195 CDD:223021 60/187 (32%)
Nucleoporin_FG2 136..>525 CDD:374260 60/289 (21%)
Nup62NP_001286489.1 Nsp1_C 194..300 CDD:309972 23/135 (17%)
SMC_N <213..392 CDD:330553 30/161 (19%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R852
SonicParanoid 00.000 Not matched by this tool.
11.030

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