Protein Alignment subdued and CG6938

DIOPT Version :9

• Sequence 1: NP_001189248.1
• Gene: subdued / 42340
• FlyBaseID: FBgn0038721
• Length: 1099
• Species: Drosophila melanogaster
• Sequence 2: NP_001261733.1
• Gene: CG6938 / 39362
• FlyBaseID: FBgn0036235
• Length: 1245
• Species: Drosophila melanogaster
• Alignment Length: 1162
• Identity: 381/1162 - (32%)
• Similarity: 576/1162 - (49%)
• Gaps: 221/1162 - (19%)

  Fly    10 GALEEATSPP------PFSKDESFQLLERSPHNPAISPTTTVPLEPPF--TTPLAPFDMELMKRH 66
            |||.::...|      |.....|.|    :.||        ||::.|.  .||:.|
  Fly   122 GALIDSDLQPRHVESDPIDSVYSCQ----ASHN--------VPVDSPSKPATPIPP--------- 165

  Fly    67 NLHERLTGKESFWRGRDTSQRFLDQEQLSASRESLGAA---------------DKRARFAESNAP 116
                                    :.:|||||...|:|               :....|.:|||.
  Fly   166 ------------------------KSKLSASRARAGSAAYTEKWLNSSVMRTSNGNPLFPKSNAI 206

  Fly   117 TLQLP-----ESAEP---RANGKRPTGN----------RTNPSNPAAPLLPMTDPDFVKGNVGGV 163
            ...||     :||||   :|.|.:..||          |.:.....:|.|...|      .|...
  Fly   207 ARPLPTHLEADSAEPSPTQAFGPKIVGNNDEDIPGTAMRRSLGLNLSPTLGSAD------RVNQS 265

  Fly   164 YDDRECS----CPREFYQRGEINT----------------------------------------- 183
            |:..|.|    .|.:|..|..|.|
  Fly   266 YEVMESSHSNVLPDQFGYRQLIPTERKASDTASSVSGSYYGSRKASKSNSLGGESGDERRVSKQD 330

  Fly   184 -------SLFFEDCVRSIDFVLAYR---INAHEPTELENTEKRRVFEANLISQGLEVESSQKDQ- 237
                   ||.|.|..|.:|.|||:.   :......|.:..:.||.|..|||.:|||||...|.|
  Fly   331 REGLDPESLMFRDGRRKVDMVLAWEEEDLGVMTEAEAKRRDNRRSFMENLIKEGLEVELEDKSQS 395

  Fly   238 ----IWFVKIHAPLEVLRRYAEILKLRMPMKESL-CNLRIS--ERSNRLRNAAHYLTNKIPGMSV 295
                .:|:|||.|..:..|.||::.|::|:|..: .:::.|  |.:..|||..::
  Fly   396 FNEKTFFLKIHLPWRLETRLAEVMNLKLPVKRFITISVKPSWDEENVVLRNMQYW---------- 450

  Fly   296 VNRSTKSVFSSLKHVFQFFLRNIYVDEEIFPKRAHRFTAIYSRDKEYLFDIR-QDCFFTTAVRSR 359
                        |.|:|...:.|.:|:.:.........|..:.:.|..|.:: :...||:|.||.
  Fly   451 ------------KDVWQRLTKKIQLDQTLLEGETTFKAATANGNPEEQFIVKDRATAFTSAQRSL 503

  Fly   360 IVEFILDRQRFPAKNQHDMAFGIERLIAEGVYSAAYPLHDGEITETGTM-----RALLYKHWASV 419
            :|..:|.|..|...::.    ||.||:.:|.|...:|||:|......:.     |.:||:.||..
  Fly   504 MVMQVLIRTPFDESDRS----GIRRLMNDGTYLGCFPLHEGRYDRPHSSGISLDRRVLYQTWAHP 564

  Fly   420 PKWYRYQPLDDIKEYFGVKIGLYFAWLGYYTYMLLLASIVGVICFLYSWFSL--KNYVPVKDIC- 481
            .:||:.|||..:::|||.||.|||.|||:||.||:..::||.:||:|...:|  ::..|.|:||
  Fly   565 SQWYKKQPLCLVRKYFGDKIALYFCWLGFYTEMLVYPAVVGTLCFIYGLATLESEDNTPSKEICN 629

  Fly   482 QSGNTNITMCPLCD-WCNFWDLKETCNYAKVTYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEI 545
            :.|..|||:||||| .|::..|.|:|.::::|||.|||||||||:|||||||.|||||||..:.:
  Fly   630 EYGTGNITLCPLCDKACSYQRLSESCLFSRLTYLFDNPSTVFFAIFMSFWATTFLELWKRKQSVL 694

  Fly   546 THRWDLTGFDVHEEHPRPQYLARLEHIPPTRVDYVTNIKEPTVPFWRMKLPATVFSFSVVLLLIA 610
            ...|||...|:.||: ||::..   :....|::.||..|||.:..|...: ..|.:.|.||.:|:
  Fly   695 VWEWDLHNVDMDEEN-RPEFET---NATTFRMNPVTREKEPYMSTWNRSI-RFVITGSAVLFMIS 754

  Fly   611 LAFVALLAVVVYRMSMLAALKVGASPMTTSSAIVLATASAAFVNLCLLYILNYMYNHLAEYLTEL 675
            :...|:|..::||:::::.:..|........|.:..:.:||.:||.::.||..:|:.:|..||.|
  Fly   755 VVLSAVLGTILYRITLVSVIYGGGGFFVKEHAKLFTSVTAALINLVVIMILTRIYHRMAIKLTNL 819

  Fly   676 EMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIAFFKGKFVGHPGE----YNKLFDYRQEECSSGG 736
            |..||.|:::||.|.||:..:|:|:|:|:.|||||||:|..:||:    .::.|..:.:.|...|
  Fly   820 ENPRTHTEYEDSYTFKIFFFEFMNFYSSLIYIAFFKGRFFDYPGDDQARKSEFFRLKNDICDPAG 884

  Fly   737 CLTELCIQLAIIMVGKQAFNTILEVYLPMFWRKVLAIQVGLSRLFNNTPNPDKAKDE-----RWM 796
            ||:||||||||||||||.:|..:|...|.||           ..:....:....|||     .|.
  Fly   885 CLSELCIQLAIIMVGKQCWNNFMEYLFPKFW-----------NWWRQRKHKQATKDESHLHMAWE 938

  Fly   797 RDFKLLDWGARGLFPEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRPVS 861
            :|:.:.|.|...||.|||||:|||||||:|||||||||.||||||:.|:||||.|::|..:||::
  Fly   939 QDYHMQDPGRLALFDEYLEMILQYGFVTLFVAAFPLAPLFALLNNVAEIRLDAYKMVTQARRPLA 1003

  Fly   862 QRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDMIPRLVYRHYVNKQGTLDGYLNFTLSEFKVID 926
            :||.|||.||.||..|...:|::|.|:||:|||.|||:||:...::..||.||:..:||.|...|
  Fly  1004 ERVEDIGAWYGILRIITYTAVVSNAFVIAYTSDFIPRMVYKFVYSETHTLAGYIEHSLSIFNTSD 1068

  Fly   927 SPTLYSLAGDLSNITTCRYTDFRLPPSSPEKYTLSSMFYIILACRLGFVVVFENFVALVMILVRW 991
            ....:..:....:..||:|..:|..|...|.|.||..::.:.|.||.||||||:.|.::..::::
  Fly  1069 YKEEWGASVSEKDPDTCQYRGYRNGPKDYEPYGLSPHYWHVFAARLAFVVVFEHVVFVITGIMQF 1133

  Fly   992 CIPDMSVELRDQIRREVYVTNEIIIDQEAHRARFERAKRSSSVLQTPVDQDMDAASI 1048
            .|||:..|::.|::||     :::..:..::...:||:..|..:.:......:.|||
  Fly  1134 IIPDVPSEVKTQMQRE-----QLLAKEAKYQHGIKRAQGDSQDIMSLFRDTSNRASI 1185

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
subdued	NP_001189248.1	Anoct_dimer	186..428	CDD:292796	72/258 (28%)
		Anoctamin	431..1007	CDD:282414	248/588 (42%)
CG6938	NP_001261733.1	Anoct_dimer	340..573	CDD:292796	72/258 (28%)
		Anoctamin	576..1150	CDD:282414	250/594 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	122	1.000	Domainoid score	I1430
eggNOG	1	0.900	-	-		E1_KOG2514
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	251	1.000	Inparanoid score	I1994
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	1	1.000	-	-		FOG0000156
OrthoInspector	1	1.000	-	-		otm43787
orthoMCL	1	0.900	-	-		OOG6_100405
Panther	1	1.100	-	-	P	PTHR12308
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1964
SonicParanoid	1	1.000	-	-		X144
	11	10.900