Protein Alignment subdued and wwk

DIOPT Version :10

• Sequence 1: NP_001189248.1
• Gene: subdued / 42340
• FlyBaseID: FBgn0038721
• Length: 1099
• Species: Drosophila melanogaster
• Sequence 2: NP_609738.1
• Gene: wwk / 34886
• FlyBaseID: FBgn0028879
• Length: 1338
• Species: Drosophila melanogaster
• Alignment Length: 837
• Identity: 209/837 - (24%)
• Similarity: 335/837 - (40%)
• Gaps: 231/837 - (27%)

  Fly   186 FFEDCV-RSIDFVLAYRINAHEPTELENTEKRRVFEANLISQGLEVESSQKDQIWFVKIHAPLEV 249
            |.||.. .::.::|| ||.:..|..|           .|:.|....||::::..:   :.||:.|
  Fly   114 FPEDAPDEALRWLLA-RIRSQPPAGL-----------GLLVQVKAHESTRRNAFY---VSAPVNV 163

  Fly   250 LRRYAEILKLRMPMKESLCNLRISERSNRLRNAAHYLTNKIPGMSVVNR--STKSVFSSLKHVFQ 312
            |.:.||  :.|:|              .|||          |.:....|  :|:.     .|.||
  Fly   164 LFKAAE--EARLP--------------KRLR----------PDLGGALREFTTRE-----SHCFQ 197

  Fly   313 FFLRNIYVDEEIFPKRAHRFTAIYSRDKEYLFDIRQDCFFTTAVRSRIVEFILDRQRFPAKNQHD 377
             .||.......:|..:..::..:     :.|..:|..|....|:..|..  :.:.|...|..|.
  Fly   198 -QLRGDVGSTALFTSQERQWLVL-----QVLQGLRAGCSDIEALHGRAA--VAEGQSIVATWQE- 253

  Fly   378 MAFGIERLIAEGVYSAAYPLHD-GEITETGTMRALLYKHWASVPKWYRYQPLDDIKEYFGVKIGL 441
                      .|:.:..:|||: ..:|:       |..||  |.:.:..||||||..|||||:.|
  Fly   254 ----------SGLITQVFPLHEPSSLTQ-------LQTHW--VKQIFAPQPLDDIAAYFGVKVAL 299

  Fly   442 YFAWLGYYTYMLLLASIVGVICFLYSWFSLKNYVPVKDICQSGNTNITMCPLCDWCNFWDLKETC 506
            ||||||:||..|.:.::.|.|.:                                |..|...:|.
  Fly   300 YFAWLGHYTCALGVPAVFGTILY--------------------------------CILWGKGQTA 332

  Fly   507 NYAKVTYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRW-------DLTGFDVHEEHPRPQ 564
                     .:...|.|::|...||:|:||.|||||.|:..||       :|.      |.|||.
  Fly   333 ---------QDMGHVLFSLFNVAWASLYLEAWKRYSVELAFRWGTLSTPPELL------EPPRPL 382

  Fly   565 YLARLEHIPPTRVDYVTNIKEP-TVPFWRMKLPATVFSFSVVLLLIALAFVALLAVVVYR----- 623
            |...||.      :.||...|| ..|.|:.:....:.||.::...:.:.|..:..::.::
  Fly   383 YKGPLEE------NNVTGRLEPKEAPAWQRRAFRYLVSFPIIGCCLCVVFAVMFLMLRFQDWWDS 441

  Fly   624 ----MSMLAALKVGASPMTTSSAIVLATASAAFVNLCLLYILNYMYNHLAEYLTELEMWRTQTQF 684
                .|:|..|.|       ...::||.|         :.:::..|..||.:|.:.|.:|.|:::
  Fly   442 KLPEESVLCCLSV-------IPKVLLAGA---------ITLMDEAYFKLAVWLNDRENYRLQSKY 490

  Fly   685 DDSLTLKIYLLQFVNYYASIFYIAFFKGKFVGHPGEYNKLFDYRQEECSSGGCLTELCIQLAIIM 749
            ::.|..|:.|.||||.:.|:|||||:                .|.||        :|..|||.::
  Fly   491 ENHLIAKVALFQFVNSFLSLFYIAFY----------------LRDEE--------KLKEQLAGLL 531

  Fly   750 VGKQAFNTILEVYLPMF---WR------------------------KVLAIQVGLSRLFNNTPNP 787
            :.:|....:.|..:|.|   |:                        ::...:..|......||..
  Fly   532 ISRQIIGNLRESAIPYFLEQWKLAKLSFNMWGALSPTQNVTRSLAEELATAEAELKAESTGTPTK 596

  Fly   788 DKAKDERWMRDFKLLD-----WGARGLFPEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRL 847
            .:..:....|:....:     :...|.|.::|||::|.|:|.:|.||||||...||:||::|:|.
  Fly   597 SQQPESSSKRNIGQAEIESSLYKYDGTFSDHLEMLVQMGYVVLFSAAFPLAGVCALINNLMEIRS 661

  Fly   848 DAKKLLTHHKRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFT---SDMIPRLVYRHYVNKQG 909
            ||.||...|:||..|||.:||.|...|..:...:||.|..:|..:   |.:.|.|.....:....
  Fly   662 DAFKLAHVHQRPFGQRVANIGTWQNALSILSLAAVIVNCALIGLSGQVSRLWPGLTTAQTIILIV 726

  Fly   910 TLDGYLNFTLSEFKVIDSPTLYS-LAGDLSNITTCRY------TDFRLPPSSPEKYT 959
            ||: ::...|.:......|.|.| ||.:::....||.      |..|..|.:|:..|
  Fly   727 TLE-HIMLGLRQALTWLLPELPSWLAAEIARAEHCRREMQCKGTSPRPTPPTPQSTT 782

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
subdued	NP_001189248.1	Anoct_dimer	186..428	CDD:465044	51/245 (21%)
		Anoctamin	431..1007	CDD:461349	154/588 (26%)
wwk	NP_609738.1	Anoctamin	289..756	CDD:461349	147/560 (26%)