Protein Alignment subdued and CG10353

DIOPT Version :10

• Sequence 1: NP_001189248.1
• Gene: subdued / 42340
• FlyBaseID: FBgn0038721
• Length: 1099
• Species: Drosophila melanogaster
• Sequence 2: NP_727578.3
• Gene: CG10353 / 32148
• FlyBaseID: FBgn0030349
• Length: 1029
• Species: Drosophila melanogaster
• Alignment Length: 898
• Identity: 361/898 - (40%)
• Similarity: 530/898 - (59%)
• Gaps: 76/898 - (8%)

  Fly   176 YQRGEINTSLFFEDCVRSIDFVLAYRINAHEPTELENTEKRR---VFEANLISQGLEVESSQKDQ 237
            |.:.:..|...|:|..||:||||||    :..|:||  |.||   :|||||..:||::|.::..:
  Fly   172 YSQWKSRTYRRFDDGKRSVDFVLAY----NGETQLE--EHRRKCEIFEANLQREGLQLEHNKVQR 230

  Fly   238 IWFVKIHAPLEVLRRYAEILKLRMPMKESLCNLRISERSNRLRNAAHYLTNKIPGMSVVNRSTKS 302
            :.|:|||||.|||.|||||||:::|:|.      |..:......:||..      .:..:|..||
  Fly   231 VHFIKIHAPAEVLYRYAEILKIKVPLKP------IPGQDQIFAESAHEF------KTCFSRMCKS 283

  Fly   303 VFSSLKHVFQFFLRNIYVDEEIFPKRAHRFTAIYSRDKEYLFDIRQDCFFTTAVRSRIVEFILDR 367
            :|||           :.::..:||:|..|....:||:...|:|.....|...:.|..|:.|||.|
  Fly   284 LFSS-----------VQLNTALFPEREPRIHLEFSRNYLELYDTEHPNFLDASTRYSIINFILQR 337

  Fly   368 QRFPAKNQHDMAFGIERLIAEGVYSAAYPLHDGEITETGTMRALLYKHWASVPKWYRYQPLDDIK 432
            |||....:.....|||:|:.:|||:.||.|||.:      .|..|.|.||::.||...||||.||
  Fly   338 QRFVEGEETADNLGIEKLVQDGVYTCAYTLHDKD------DRDRLLKEWANISKWKNLQPLDQIK 396

  Fly   433 EYFGVKIGLYFAWLGYYTYMLLLASIVGVICFLYSWFSLKNYVPVKDICQSGNTNITMCPLCD-W 496
            :|||.|:.|||||||:||.||:..|:.||:||||.:.:..:....:|||....|  .|||.|| .
  Fly   397 DYFGAKVALYFAWLGFYTQMLIPISVFGVLCFLYGFITWNSDPISRDICDDNGT--IMCPQCDRS 459

  Fly   497 CNFWDLKETCNYAKVTYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHEEHP 561
            |::|.|.|||..:|..|||||..||.||..|:.||.::||.||||||.:.|||.||||..|.|||
  Fly   460 CDYWRLNETCTSSKFNYLIDNNMTVVFAFSMAIWAVVYLEFWKRYSAGLVHRWGLTGFTHHVEHP 524

  Fly   562 RPQYLARLEHIPPT-----RVDYV--TNIKEPTVPFWRMKLPATVFSFSVVLLLIALAFVALLAV 619
            |||||||:......     ..|:.  ..|.:|.||||..|......|:|:::|.|.::.:|:..:
  Fly   525 RPQYLARISRTKKLAGKAYEQDHTGKRTILDPDVPFWSFKFLPNFTSYSIMVLFICISVIAIAGI 589

  Fly   620 VVYRMSMLAALKVGASPMTTSSAIVLATASAAFVNLCLLYILNYMYNHLAEYLTELEMWRTQTQF 684
            ::|||:..|:..:..|..:.:..:::...:|..::|.::.:|:.:|::||..||..|..||||::
  Fly   590 IIYRMAQRASHSILGSENSMTFKVMILPMTAGIIDLIVISLLDMVYSNLAVKLTNYEYCRTQTEY 654

  Fly   685 DDSLTLKIYLLQFVNYYASIFYIAFFKGKFVGHPGEYNKLFDYRQEECSSGGCLTELCIQLAIIM 749
            |:|||:|.|:.||||||:|:|||||.||||||:|.:||::..:|||||:.||||.|||:||.|||
  Fly   655 DESLTIKNYVFQFVNYYSSLFYIAFLKGKFVGYPAKYNRVLGFRQEECNPGGCLMELCMQLVIIM 719

  Fly   750 VGKQAFNTILEVYLPMFWR--KVLAIQVGLSRLFNNTPNPDKAKDER------WMRDFKLLDWGA 806
            .||||.|.|:|:.:|...|  |.|:.:.|..:         ..:|:|      :..|:.||....
  Fly   720 AGKQAVNAIVEMLIPYLMRTFKELSYRHGWYK---------SHQDQRLVPYNQFTEDYNLLPAEN 775

  Fly   807 RGLFPEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRPVSQRVRDIGVWY 871
            ..|:.||||||:|:||:|:|..||||||..|||||::|:||||.|:|...:|||..|.||||||:
  Fly   776 NSLYVEYLEMVVQFGFITLFSLAFPLAPLLALLNNVIEVRLDAIKMLRFLRRPVGMRARDIGVWH 840

  Fly   872 RILDCIGKLSVITNGFIIAFTSDMIPRLVYRHYVNKQGTLDGYLNFTLSEFKVIDSPTLYSLAGD 936
            .|:..:.:::|.::..||||::::||::||...:. ...|:.||||||:.|...|......|.|.
  Fly   841 SIMTVVTRIAVASSAMIIAFSTNLIPKIVYAASMG-DPELNNYLNFTLAVFNTKDFQVQPLLGGS 904

  Fly   937 LS-NITTCRYTDFRLPPSSPEKYTLSSMFYIILACRLGFVVVFENFVALVMILVRWCIPDMSVEL 1000
            .. |.|.||||:||..|..|..|....:::.||..||.|:|:::|.:.::..::||.:||:|..|
  Fly   905 QHVNETVCRYTEFRNSPEDPHPYKRPMIYWKILTGRLAFIVIYQNIITMLQGILRWAVPDVSGRL 969

  Fly  1001 RDQIRREVYVTNEIIIDQEAHRARFERAKRSSSVLQTPVD-QDMDAASIQEPN 1052
            ..:|:||.::..|.||:.|...|        ..::||.:: |......:::.|
  Fly   970 LKRIKRENFLLREHIIEYEKQHA--------MKLVQTELNGQQKSEGELRQRN 1014

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
subdued	NP_001189248.1	Anoct_dimer	186..428	CDD:465044	89/244 (36%)
		Anoctamin	431..1007	CDD:461349	256/592 (43%)
CG10353	NP_727578.3	Anoct_dimer	183..392	CDD:465044	89/243 (37%)
		Anoctamin	395..976	CDD:461349	256/592 (43%)