Protein Alignment subdued and Ano10

DIOPT Version :9

• Sequence 1: NP_001189248.1
• Gene: subdued / 42340
• FlyBaseID: FBgn0038721
• Length: 1099
• Species: Drosophila melanogaster
• Sequence 2: XP_038938700.1
• Gene: Ano10 / 301111
• RGDID: 1308260
• Length: 712
• Species: Rattus norvegicus
• Alignment Length: 882
• Identity: 199/882 - (22%)
• Similarity: 337/882 - (38%)
• Gaps: 246/882 - (27%)

  Fly   212 NTEKRRVFEANLIS-QGL--EVESSQKDQIWFVKIHAPLEVLRRYAEILKLRM--PMKESLCNLR 271
            |.|:|.|...:|.. :|:  .|::.:......|.|....:|.....|.||.|:  |.|:....|.
  Rat    11 NVEERPVHGVSLSKMKGILSTVDTCESSFTPLVVIELAQDVKEETKEWLKSRIISPKKDGGAQLL 75

  Fly   272 ISERSNR-----LRNAAHYLTNK-----IPGMSVVNRSTKSVFSSLKHVFQFFLRNIYVDEEIFP 326
            .....|:     |.|...||...     :.|...|. ..|.........|.:..|
  Rat    76 FRPLLNKYEKETLENQNLYLVGASNIRLLLGAEAVG-LVKECTDGAMRAFTYRTR---------- 129

  Fly   327 KRAHRFTAIYSRDKEYLFDIRQDCFFTTA-----VRSRIVEFILDRQRFPAKNQHDMAFG---IE 383
               |.|...:..:.::|  ...:|.|...     :|:|      |.:..|...|..:..|   :.
  Rat   130 ---HNFKGFHGNNDDFL--TMAECQFIIKHELENLRAR------DEKMIPGYPQAKLYPGKSLMR 183

  Fly   384 RLIAEGVYSAAYPLHDGE----ITETGTMRALLYKHWASVPKWY-----RYQPLDDIKEYFGVKI 439
            ||:..|:.:..:||||.|    :.:|                ||     :|||:|.|:.|||..|
  Rat   184 RLLTSGIVTQVFPLHDTEALKKLEDT----------------WYTRFALKYQPIDSIRGYFGETI 232

  Fly   440 GLYFAWLGYYTYMLLLASIVGVICFLYSWFSLKNYVPVKDICQSGNTNITMCPLCDWCNFWDLKE 504
            .|||.:|.|:|:.|:..:::|:..:|:.|.....|
  Rat   233 ALYFGFLEYFTFALIPMAVIGLPYYLFVWEDYDKY------------------------------ 267

  Fly   505 TCNYAKVTYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHEEHPRPQYLARL 569
                            |.||.|...|:|:.||:|||..|.:|:||.........|.|||.:...|
  Rat   268 ----------------VIFASFNLIWSTVILEVWKRGCANMTYRWGTLVMKRQFEEPRPGFHGVL 316

  Fly   570 EHIPPTRVDYVTNIKEPTVPFWRMKLPATVFSFSVVLLLIALAFVALLAVVVYRMSMLAALKVGA 634
                  .::.||..:||....::.:|...:.|...|.|.:   :.:|..:::|......||.:..
  Rat   317 ------GINSVTGREEPVYSSYKRQLRTYLVSLPFVCLCL---YFSLYVMMIYFDMEDWALSLHE 372

  Fly   635 SPMTTSSAIVLATASAAFVNLCLLYILNYMYNHLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVN 699
            ...:..::::|...|..:.  .::.|:|.:|.:.||:||..|..|.::.:.:.|.||:.:..|:|
  Rat   373 DSGSEWTSLLLYVPSIVYA--IVIEIMNRLYRYAAEFLTSWENHRLESAYQNHLVLKVLVFNFLN 435

  Fly   700 YYASIFYIAFFKGKFVGHPGEYNKLFDYRQEECSSGGCLTELCIQLAIIMVGKQAFNTILEVYLP 764
            .:||:|||||.....        ||.  ||              .||.:::..|..|.::|..||
  Rat   436 CFASLFYIAFVLKDM--------KLL--RQ--------------SLATLLITSQILNQVVESLLP 476

  Fly   765 MFW----------RKVLAIQVGLSRLFNNTPNPDKAKDERWMRDFKLLDWGARGLFPEYLEMVLQ 819
             :|          |||.|::..:     :|...::...|:.|..:       .|.|.:|||:.||
  Rat   477 -YWLQRKYCARVKRKVRALKSDV-----DTTLYEQVLLEKEMGTY-------LGTFDDYLELFLQ 528

  Fly   820 YGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRPVSQRVRDIGVWYRILDCIGKLSVIT 884
            :|:|::|...:|||..||:|||..|:..||.|:....|||.|:....||||....:.:..:||:|
  Rat   529 FGYVSLFSCVYPLAAAFAVLNNFTEVNSDALKMCRVFKRPFSEPSASIGVWQLAFETMSVISVVT 593

  Fly   885 NGFIIAFTSDMIPRLVYRHYVNKQGTLDGYLNFTLSEFKVIDSPTLYSLAGDLSNITTCRYTDFR 949
            |..:|.    |.|:                :|....|.|                      ||..
  Rat   594 NCALIG----MSPQ----------------VNAVFPESK----------------------TDLV 616

  Fly   950 LPPSSPEKYTLSSMFYIILACRLGFVVVFENFVALVMILVRWCIPDMSVELRDQIRREVYVTNEI 1014
            |                       .||..|:.:..:..::.:.|||....::.::.|..:.:.|.
  Rat   617 L-----------------------IVVAVEHALLALKFILAFAIPDKPRHIQMKLARLEFESLEA 658

  Fly  1015 IIDQEAHRARFERAKRSSSVLQTPVDQDMDAASIQEP 1051
            :..|:....       :.|:.:...:::.:||:.:.|
  Rat   659 LKQQQMKLV-------AESLKEESQEEEKEAAACRMP 688

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
subdued	NP_001189248.1	Anoct_dimer	186..428	CDD:292796	51/247 (21%)
		Anoctamin	431..1007	CDD:282414	139/585 (24%)
Ano10	XP_038938700.1	Anoctamin	224..650	CDD:398306	139/584 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920