Protein Alignment subdued and ano10

DIOPT Version :10

• Sequence 1: NP_001189248.1
• Gene: subdued / 42340
• FlyBaseID: FBgn0038721
• Length: 1099
• Species: Drosophila melanogaster
• Sequence 2: XP_002937896.1
• Gene: ano10 / 100487513
• XenbaseID: XB-GENE-955754
• Length: 651
• Species: Xenopus tropicalis
• Alignment Length: 859
• Identity: 202/859 - (23%)
• Similarity: 336/859 - (39%)
• Gaps: 263/859 - (30%)

  Fly   206 EPTELENTEKRRVFEANLISQGLEVESSQKDQIWFVKIHAPLEVLRRYAEILKLRMPMKESLCNL 270
            :|.:||       |:..::.: |..::.::.:.|.||               |:|...|:....|
 Frog     9 DPPDLE-------FQPLVVIE-LAKDAKEETREWLVK---------------KIRDKKKDGGTQL 50

  Fly   271 RISERSNRLRNAAHYLTNKIPGMSVVNRSTKSVFSSLKHVFQFFLRNIYVDEEIFPKRAHRFTAI 335
            .|  :...:.|...|:       .||..|||.:....:.|   .:....:|..:.|       .|
 Frog    51 LI--KPLVISNDEEYI-------YVVGGSTKRLLLGAESV---GMVKECIDGSMKP-------FI 96

  Fly   336 YSRDKEYLFDIRQD--CFFTTAVRSRIVEFILDRQR---------------FPAKNQHDMAFGIE 383
            ||..|||. |..:|  .|.:.|....|:::.||..|               :|.|:.      ..
 Frog    97 YSNRKEYK-DWTEDGENFLSMADCQYIIKYELDNLRAQDEKNIPGYPNSKLYPGKSI------FR 154

  Fly   384 RLIAEGVYSAAYPLHDGEITETGTMRALLYKHWASVPKWY-----RYQPLDDIKEYFGVKIGLYF 443
            ||...|:....:||||.|     .::.|  :|     :||     .:||:|.|:.|||..:||||
 Frog   155 RLKTSGIMIQVFPLHDKE-----ELKRL--RH-----QWYLRIKLAFQPIDQIQHYFGDTLGLYF 207

  Fly   444 AWLGYYTYMLLLASIVGVICFLYSWFSLKNYVPVKDICQSGNTNITMCPLCDWCNFWDLKETCNY 508
            |:|.|:|..|:..:::|:..:.:.|.....|
 Frog   208 AFLEYFTMALIPMALIGIPYYFFDWEDYDKY---------------------------------- 238

  Fly   509 AKVTYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHEEHPRPQYLARLEHIP 573
                        |.||.|...|:|:.||:|||.|:.:|:||.........|.|||.:...|
 Frog   239 ------------VIFATFNLVWSTVILEVWKRLSSAMTYRWGSLIMKRKFEEPRPGFHGVL---- 287

  Fly   574 PTRVDYVTNIKEPTVPFWRMKLPATVFSFSVVLLLIALAFVALLAVVVYRMSMLAALKVGASPMT 638
              .::.||..|||....::.:|  .::..||..:.:.| ::|:..:::|......||.......:
 Frog   288 --GINPVTGRKEPIYSSFKRQL--RIYLVSVPFVCVCL-YLAIYVMMIYFDLEHWALAYHQEQQS 347

  Fly   639 TSSAIVLATASAAFVNLCLLYILNYMYNHLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVNYYAS 703
            |.|.::|...|..:.  .::.|||.:|...||:||..|..|.::.:.:.|.||:.:...||.:||
 Frog   348 TFSNLLLYVPSIIYA--VVIEILNRIYKIAAEFLTSWENHRLESSYQNHLVLKVLVFNIVNCFAS 410

  Fly   704 IFYIAFFKGKFVGHPGEYNKLFDYRQEECSSGGCLTELCIQ-LAIIMVGKQAFNTILEVYLPMFW 767
            :|||||..                         |..:|..| ||.:::..|..|..:|..|| :|
 Frog   411 LFYIAFVM-------------------------CDMKLLRQSLATLLITSQILNQFVEALLP-YW 449

  Fly   768 RKVLAIQVGLSRLFNNTPNPDKAKDERWMRDFKLLDW--------GARGLFPEYLEMVLQYGFVT 824
                 :|...||....     |.|......|:.||:.        ...|.|.:|||:.|.:|:|:
 Frog   450 -----LQKRSSRKIKK-----KVKSLNVDTDYTLLEQIHLEKDMDTYLGTFDDYLELFLLFGYVS 504

  Fly   825 IFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRPVSQRVRDIGVWYRILDCIGKLSVITNGFII 889
            :|...:|||..||:|||:.||..||.|:...:|||.||...:||||....:.:|.::|:||
 Frog   505 LFSCVYPLAAIFAVLNNLTEMYSDALKMCRVYKRPFSQPSANIGVWMLAFETMGIIAVVTN---- 565

  Fly   890 AFTSDMIPRLVYRHYVNKQGTLDGYLNFTLSEFKVIDSPTLYSLAGDLSNITTCRYTDFRLPPSS 954
                                                  .||..::..:|.:......|..|
 Frog   566 --------------------------------------CTLLGMSSQVSTLFQDSKRDLIL---- 588

  Fly   955 PEKYTLSSMFYIILACRLGFVVVFENFVALVMILVRWCIPDMSVELRDQIRR------------- 1006
                |::::.:.:||  |.|::.|             .|||...:::.::.|
 Frog   589 ----TVAAIEHALLA--LKFILAF-------------VIPDKPYDIQVKLARLEFESMEALKKNQ 634

  Fly  1007 EVYVTNEIIIDQEA 1020
            ::.:::|.:.|.||
 Frog   635 QMKLSSESLTDDEA 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
subdued	NP_001189248.1	Anoct_dimer	186..428	CDD:465044	52/243 (21%)
		Anoctamin	431..1007	CDD:461349	144/597 (24%)
ano10	XP_002937896.1	Anoctamin	195..621	CDD:461349	143/583 (25%)