Protein Alignment subdued and ano11

DIOPT Version :10

• Sequence 1: NP_001189248.1
• Gene: subdued / 42340
• FlyBaseID: FBgn0038721
• Length: 1099
• Species: Drosophila melanogaster
• Sequence 2: XP_009295190.1
• Gene: ano11 / 100007289
• ZFINID: ZDB-GENE-090313-245
• Length: 893
• Species: Danio rerio
• Alignment Length: 959
• Identity: 360/959 - (37%)
• Similarity: 525/959 - (54%)
• Gaps: 141/959 - (14%)

  Fly   122 ESAEPRANGKRPTGNRTNPS--NPAAPLLPMTDPDFVKGNVGGVYDDRECSCPREFYQRGEINTS 184
            |:..|.:.|....|....|.  |.||.  ...||.:       |:.::..|.|..       :|.
Zfish    23 EAHAPDSYGSLQNGGFIPPRYLNTAAN--DDDDPIY-------VHCEQTASAPVH-------HTG 71

  Fly   185 LFFEDCVRSIDFVLAYRI----------------NAHEPTELENTEKRR---------VFEANLI 224
            .:|.|....|||||.:.:                .|.||.:.|:..:||         .|..||.
Zfish    72 NYFRDGQTKIDFVLVWEVKVRRKRRSRGQAEASEGAAEPAQEESRSERRKAQLARWRDKFILNLQ 136

  Fly   225 SQGL----EVESSQKDQIWFVKIHAPLEVLRRYAEILKLRMPMKESLCNLRISERSNRLRNAAHY 285
            :.||    |..||.|..|.::|:|||.:||..|||.|.||.|::
Zfish   137 TAGLLMEKEESSSVKKTIHYLKLHAPWDVLVYYAEELCLRAPLQ--------------------- 180

  Fly   286 LTNKIPGMSVVNRSTKSVFSSLKHVFQ-FFLRNIYVDEEIFPKR-AHRFTAIYSRDKEYLF---D 345
                        ......|::...|.| .::.||..|.  .|.| ...:|..:.:.|...|   |
Zfish   181 ------------AQPHPDFNTSARVLQKLWVPNIMKDS--VPNRPVDYYTCAFRKSKMEKFLGSD 231

  Fly   346 IRQDCFFTTAVRSRIVEFILDRQRFPAKNQHDMAFGIERLIAEGVYSAAYPLHDGEI------TE 404
            .|:: :||:..|.|||..||.|..:..:.:.::  |:.||:.:|.::.|:|||:|..      |:
Zfish   232 DREN-YFTSTQRHRIVYEILARTAYGRRKRAEV--GVARLLRDGAFTGAFPLHEGPFKLPSCDTQ 293

  Fly   405 TGTM--RALLYKHWASVPKWYRYQPLDDIKEYFGVKIGLYFAWLGYYTYMLLLASIVGVICFLYS 467
            ...:  |.:||.:|||..||.:|||||.|:||||.||.|||||||:||..||.|::||...|:..
Zfish   294 PDQLNKRQVLYHYWASWLKWCKYQPLDHIREYFGEKIALYFAWLGFYTAWLLPAALVGTCVFVSG 358

  Fly   468 WFSLKNYVPVKDICQSGNTNITMCPLCDWCNFWDLKETCNYAKVTYLIDNPSTVFFAVFMSFWAT 532
            ..::.:..|.|:||:||...: |||||:.|..|::.:.|..|||.||.|:|.||||:||||.||.
Zfish   359 ILTMGSNTPAKEICESGGLYL-MCPLCETCKPWNMSDICPMAKVGYLFDHPGTVFFSVFMSLWAV 422

  Fly   533 LFLELWKRYSAEITHRWDLTGFDVHEEHPRPQYLARLEHIPPTRVDYVTNIKEPTVPFWRMKLPA 597
            .|||.|||.:|.:.|.||...|...||.|||::.|.   .|....:.||.:|||..| .:.::..
Zfish   423 TFLEYWKRKNATLAHHWDCMDFHEDEEPPRPEFAAM---APAMEENPVTGVKEPYFP-EKARISR 483

  Fly   598 TVFSFSVVLLLIALAFVALLAVVVYRMSMLAAL--KVGASPMTTSSAIVLATASAAFVNLCLLYI 660
            .:....|:::::.:..:.|:.|::|| |:::.:  :.|:|.:.|.:..: |..|:..|||.|:.:
Zfish   484 MLTGSMVIVIMLCVVMIFLVTVIIYR-SIVSVMMFETGSSVLRTQAGNI-ANISSTLVNLALILL 546

  Fly   661 LNYMYNHLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIAFFKGKFVGHPGEYNKLF 725
            :..:|..|||.||:.||.|||||::|:.|.|:::.||||:|:|.||:|||||:|||:||.|..||
Zfish   547 MGQVYTALAEQLTKWEMHRTQTQYEDAFTFKVFIFQFVNFYSSPFYVAFFKGRFVGYPGHYGTLF 611

  Fly   726 DYRQEECSSGGCLTELCIQLAIIMVGKQAFNTILEVYLPMF--WRKVLAIQVGLSRLFNNTPNPD 788
            ..|.|:|..||||.||..||.|||||||..|.|.|..:|..  ||:        .|...:.....
Zfish   612 GMRNEDCGPGGCLIELAEQLCIIMVGKQLINNIQEFVIPKIKAWRQ--------KRALASVKKAQ 668

  Fly   789 KAKD-ERWMRDFKLLDWGARGLFPEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKL 852
            |.:: |||.:|::|:.  ..|||.||||:|||:||:|||||||||||.||||||.:|:||||.|.
Zfish   669 KTQEPERWEQDYELIP--CEGLFDEYLEIVLQFGFITIFVAAFPLAPLFALLNNWVEVRLDAHKF 731

  Fly   853 LTHHKRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDMIPRLVYRHYVNKQGTLDGYLNF 917
            :..::|||::|.:.||||:.||:.:..:||:.|.|:||||||.:|||:|::..|..  |.||:||
Zfish   732 VCEYRRPVAERAQHIGVWFIILEALSHVSVVVNAFLIAFTSDFLPRLLYQYKFNND--LHGYVNF 794

  Fly   918 TLSEFKVIDSPTLYSLAGDLSNITTCRYTDFRLPPSSPEKYTLSSMFYIILACRLGFVVVFENFV 982
            ||:.     ||..|    :.|:.|.|||..||   ....||.|  :::.:||.||||::.||:.|
Zfish   795 TLAY-----SPPSY----NHSSHTVCRYKAFR---DENGKYKL--VYWELLAVRLGFIIAFEHVV 845

  Fly   983 ALVMILVRWCIPDMSVELRDQIRREVYVTNEIIID-QEAHRARFERAKR 1030
            ..|:.::.|.:||:...|:.:|:||.|:..:.:.| |||    ..:|||
Zfish   846 FFVLRVIDWMVPDIPESLQLKIKRERYLAKQALADNQEA----LLQAKR 890

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
subdued	NP_001189248.1	Anoct_dimer	186..428	CDD:465044	78/283 (28%)
		Anoctamin	431..1007	CDD:461349	255/580 (44%)
ano11	XP_009295190.1	Anoct_dimer	73..319	CDD:465044	78/283 (28%)
		Anoctamin	322..870	CDD:461349	255/580 (44%)