Protein Alignment CG6231 and SLC22A13

DIOPT Version :9

• Sequence 1: NP_001262734.1
• Gene: CG6231 / 42339
• FlyBaseID: FBgn0038720
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_004247.2
• Gene: SLC22A13 / 9390
• HGNCID: 8494
• Length: 551
• Species: Homo sapiens
• Alignment Length: 537
• Identity: 144/537 - (26%)
• Similarity: 234/537 - (43%)
• Gaps: 48/537 - (8%)

  Fly     3 FDQILAKCGDFNRYQFMILALFGFINIIVSMHYFTQTVISFVPDHWCYHDKLVNMTYKEIG---- 63
            |.|:||:.|||.|:|..:|.|...:|.:...::|....:.....|.|....:.|.|:....
Human     4 FVQVLAEIGDFGRFQIQLLILLCVLNFLSPFYFFAHVFMVLDEPHHCAVAWVKNHTFNLSAAEQL 68

  Fly    64 ------------EIYAQFENPSC-TRLDDINGHNVTVSSKACEKWIYNYDFGYRSMNTELNWVCD 115
                        |....|..|.. ..|.||..|....:......|.|. :....|:..|.|.|||
Human    69 VLSVPLDTAGHPEPCLMFRPPPANASLQDILSHRFNETQPCDMGWEYP-ENRLPSLKNEFNLVCD 132

  Fly   116 SAYKARIGQSLFFIGSVVGTLFYGLLSDKIGR----VPALILSNFCGFAGDFSTIFTKSVATFTL 176
            ..:.....||:|..|.:||||.:|.|.|:|||    :..|:|....|.|    |.|..|...:..
Human   133 RKHLKDTTQSVFMAGLLVGTLMFGPLCDRIGRKATILAQLLLFTLIGLA----TAFVPSFELYMA 193

  Fly   177 CRFISGLAADTNFYLMYIIVLEYIRPSMRTLGLNMAVGLFYC---LGLVFTPWLAVLVGHWQIYL 238
            .||....|.....:....::.|::.||.||    .||.|..|   ||.:....||....:|::..
Human   194 LRFAVATAVAGLSFSNVTLLTEWVGPSWRT----QAVVLAQCNFSLGQMVLAGLAYGFRNWRLLQ 254

  Fly   239 ACTSLPILLVVLYYFVVQESAQWLVTRNDIDGAIVRLKRVAKFNGCRVSQADFDEFRRHCQMTHE 303
            ...:.|.||:..|::.:.|||:||:||..:|.||..:::.|..|..::|.          ::.::
Human   255 ITGTAPGLLLFFYFWALPESARWLLTRGRMDEAIQLIQKAASVNRRKLSP----------ELMNQ 309

  Fly   304 MLGGDDKKQATLLDMFRTPRMRKNTLILFFKSMVITLCYDAVSRNVEGMGISPFIMFSLSALAVL 368
            ::..........||:||.|::||.|||:|....|.:|.|..:|..|...|:..::...:.....:
Human   310 LVPEKTGPSGNALDLFRHPQLRKVTLIIFCVWFVDSLGYYGLSLQVGDFGLDVYLTQLIFGAVEV 374

  Fly   369 PSSVLLVLLQDRIGRKGMASGSLLVGGLFTAAAGIAIAYQQHNHNAILLACLTIAARFGVAISYE 433
            |:....:.:..|.|||....|:|::|||..    |.|.:...: ..:::..|.:..:...|.::.
Human   375 PARCSSIFMMQRFGRKWSQLGTLVLGGLMC----IIIIFIPAD-LPVVVTMLAVVGKMATAAAFT 434

  Fly   434 SGSQYATELIPTCVRGQGVAAVHVAGFAASFLAPYILWLGTFFKAAPSIILGVLFFAGSFVCLLL 498
            ....|:.||.||.:|..|:..|.:.......|.|.::.||.:..|.|.:|.|.|......:|.||
Human   435 ISYVYSAELFPTILRQTGMGLVGIFSRIGGILTPLVILLGEYHAALPMLIYGSLPIVAGLLCTLL 499

  Fly   499 PETLNRSLPTTIEEGEV 515
            |||..:.|..|:::.|:
Human   500 PETHGQGLKDTLQDLEL 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	138/521 (26%)
		MFS	125..499	CDD:119392	104/380 (27%)
SLC22A13	NP_004247.2	2A0119	12..510	CDD:273328	138/521 (26%)
		MFS	139..500	CDD:119392	105/383 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	511..551		1/6 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153609
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.950