Protein Alignment CG6231 and SLC22A14

DIOPT Version :9

• Sequence 1: NP_001262734.1
• Gene: CG6231 / 42339
• FlyBaseID: FBgn0038720
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: XP_006713479.2
• Gene: SLC22A14 / 9389
• HGNCID: 8495
• Length: 675
• Species: Homo sapiens
• Alignment Length: 545
• Identity: 126/545 - (23%)
• Similarity: 227/545 - (41%)
• Gaps: 62/545 - (11%)

  Fly     3 FDQILAKCGDFNRYQFMILALFGFINIIVSMHYF---------------TQTVISFVPDHWCYHD 52
            |..:|...|:|..:|..::|| .||..|:|..:.               |..:::..| |....:
Human   133 FANLLDAVGEFGTFQQRLVAL-TFIPSIMSAFFMFADHFVFTAQKPYCNTSWILAVGP-HLSKAE 195

  Fly    53 KLVNMTYKEI--GEIYAQFEN-PSCTRLDDINGHNVTVSSKACEKWIYNYDFGYRSMNTELNWVC 114
            :| |:|..:.  |.....|.. |....||.|....:..:....:.|||. |...||:..|.:.||
Human   196 QL-NLTIPQAPNGSFLTCFMYLPVPWNLDSIIQFGLNDTDTCQDGWIYP-DAKKRSLINEFDLVC 258

  Fly   115 DSAYKARIGQSLFFIGSVVGTLFYGLLSDKIGRVPALILSNFCGFAGDFSTIFTKSVATFTLCRF 179
            ....|....|.:|..|..:|:|.:.|::||:||.||::||........|.|.|..|...:...||
Human   259 GMETKKDTAQIMFMAGLPIGSLIFRLITDKMGRYPAILLSLLGLIIFGFGTAFMNSFHLYLFFRF 323

  Fly   180 ISGLAADTNFYLMYIIVL--EYIRPSMRTLGLNMAVGLFYCLGLVFTPWLAVLVGHWQIYLACTS 242
              |::.....|.:..|.|  |::....|...:.:. ..|:.:|.|....:|..:.|||:......
Human   324 --GISQSVVGYAISSISLATEWLVGEHRAHAIILG-HCFFAVGAVLLTGIAYSLPHWQLLFLVGG 385

  Fly   243 LPILLVVLYYFVVQESAQWLVTRNDIDGAIVRLKRVAKFNGCRVSQADFDEFRRHCQMTHEMLGG 307
            :.::..:.|.:::.||.:||:.:..:..|...|...|..|...:.....||.    |:..:.:
Human   386 ILVIPFISYIWILPESPRWLMMKGKVKEAKQVLCYAASVNKKTIPSNLLDEL----QLPRKKV-- 444

  Fly   308 DDKKQATLLDMFRTPRMRKNTLILFFKSMVITLCYDAVSRNVEGMGISPFIMFSLSALAVLPSSV 372
               .:|::||..:..::.|.||::......::..|..:|..:..:|:|......:.::..:|:.:
Human   445 ---TRASVLDFCKNRQLCKVTLVMSCVWFTVSYTYFTLSLRMRELGVSVHFRHVVPSIMEVPARL 506

  Fly   373 LLVLLQDRIGRKGMASGSLLVG------GLFTAAAGIAIAYQQHNHNAILLACLTIAA----RFG 427
            ..:.|..:||||...:.:||..      .||.......:..:.....|..|..:||..    .|.
Human   507 CCIFLLQQIGRKWSLAVTLLQAIIWCLLLLFLPEGEDGLRLKWPRCPATELKSMTILVLMLREFS 571

  Fly   428 VAISYESGSQYATELIPTCVRGQGVAAVHVAGFAASFLAPYILWLGTFFKAAPSI-------ILG 485
            :|.:......|..||:||.:|..|:..|.:|..|.:.|:.      |.....||:       :|.
Human   572 LAATVTVFFLYTAELLPTVLRATGLGLVSLASVAGAILSL------TIISQTPSLLPIFLCCVLA 630

  Fly   486 VLFFAGSFVCLLLPETLNRSLPTTI 510
            ::.|:   :..|||||.::.|..::
Human   631 IVAFS---LSSLLPETRDQPLSESL 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	124/534 (23%)
		MFS	125..499	CDD:119392	87/392 (22%)
SLC22A14	XP_006713479.2	2A0119	141..650	CDD:273328	124/533 (23%)
		MFS	270..641	CDD:119392	87/391 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153855
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.940