DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6231 and HXT5

DIOPT Version :9

Sequence 1:	NP_001262734.1	Gene:	CG6231 / 42339	FlyBaseID:	FBgn0038720	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_011964.1	Gene:	HXT5 / 856496	SGDID:	S000001138	Length:	592	Species:	Saccharomyces cerevisiae

Alignment Length:	587	Identity:	112/587 - (19%)
Similarity:	188/587 - (32%)	Gaps:	206/587 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 YHDKLVNMTYKEIGEIYAQFENPSCTRLDDINGHNVTVSSKACEK-------------------- 94
            |:|.|...  |.:.. |...|.|....|:::...    ..|..||
Yeast    40 YNDNLAQA--KPVSS-YISHEGPPKDELEELQKE----VDKQLEKKSKSDLLFVSVCCLMVAFGG 97

  Fly    95 WIYNYDFGYRSMNTELNWVCDSAYKARIGQ------------------SLFFIGSVVGTLFYGLL 141
            :::.:|.|     |...:|..:.:..|.|.                  |:|.||..:|.:....|
Yeast    98 FVFGWDTG-----TISGFVRQTDFIRRFGSTRANGTTYLSDVRTGLMVSIFNIGCAIGGIVLSKL 157

  Fly   142 SD----KIGRVPALILSNFCGFAGDFSTIFTKSVAT------FTLCRFISGLAADTNFYLMYIIV 196
            .|    |||.:..:::         :|......:|:      :.:.|.||||.......|..:::
Yeast   158 GDMYGRKIGLMTVVVI---------YSIGIIIQIASIDKWYQYFIGRIISGLGVGGITVLAPMLI 213

  Fly   197 LEYIRPSMRTLGLNMAVGLFYCLGLVFTPWLAVLVGH--------------WQIYLA-CTSLPIL 246
            .|.....:|..       |..|..|:.|  ..:.:|:              |::.|. |.:..|.
Yeast   214 SEVSPKQLRGT-------LVSCYQLMIT--FGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWSIF 269

  Fly   247 LVVLYYFVVQESAQWLVTRNDIDGAIVRLKRVAK-FNGCRVSQADFDEFRRHCQMTHEMLGGDDK 310
            ::|...| |.||.::||....|:.|...|.|..| .....:...:.:.::...:.  |.|.|
Yeast   270 MIVGMTF-VPESPRYLVEVGKIEEAKRSLARANKTTEDSPLVTLEMENYQSSIEA--ERLAG--- 328

  Fly   311 KQATLLDMFR-TPRMRKNTLILFFKSMVI----------------TLCYDAVS-----RNVEGMG 353
             .|:..::.. .|:|.:.||:    .|:|                |..:.||.     .....:|
Yeast   329 -SASWGELVTGKPQMFRRTLM----GMMIQSLQQLTGDNYFFYYGTTIFQAVGLEDSFETAIVLG 388

  Fly   354 ISPFI--MFSLSALAVLPSSVLLVLLQDRIGRKGMASGSLLVGGLFTAAAGIAIAYQQHNHNAIL 416
            :..|:  .|||..:             ||.||:..         |.....|             :
Yeast   389 VVNFVSTFFSLYTV-------------DRFGRRNC---------LLWGCVG-------------M 418

  Fly   417 LACLTIAARFGVAISYESGSQ---------------------YAT-----------ELIPTCVRG 449
            :.|..:.|..||...:.:|..                     :||           |..|..|||
Yeast   419 ICCYVVYASVGVTRLWPNGQDQPSSKGAGNCMIVFACFYIFCFATTWAPVAYVLISESYPLRVRG 483

  Fly   450 QGV----AAVHVAGFAASFLAPYILWLGTFFKAAPSIILGVLFFAGSFVCLLLPETLNRSLPTTI 510
            :.:    |...:.||..||..|:|.....|:..  .:.:|.:.||..:|...:|||..    .|:
Yeast   484 KAMSIASACNWIWGFLISFFTPFITSAINFYYG--YVFMGCMVFAYFYVFFFVPETKG----LTL 542

  Fly   511 EE 512
            ||
Yeast   543 EE 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	109/582 (19%)
CG6231	NP_001262734.1	MFS	125..499	CDD:119392	89/459 (19%)
HXT5	NP_011964.1	Sugar_tr	89..549	CDD:395036	101/531 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000