DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6231 and OCT3

DIOPT Version :9

Sequence 1:	NP_001262734.1	Gene:	CG6231 / 42339	FlyBaseID:	FBgn0038720	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_173089.1	Gene:	OCT3 / 838209	AraportID:	AT1G16390	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	556	Identity:	128/556 - (23%)
Similarity:	215/556 - (38%)	Gaps:	101/556 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DQILAKC-GDFNRYQFMILALFGFINIIVSMHYF---TQTVISFVPDH---WCYHDKLVNMTYKE 61
            ::.:.:| |||...||:..||       ||..:|   .||.|:...|.   |
plant    26 EETIERCIGDFGWAQFLQAAL-------VSFAWFFDAQQTFITVFTDSQPMW------------- 70

  Fly    62 IGEIYAQFENPSCTRLDDINGHNVTVSSKAC----EKWIYNYDFGYRSMNTELNWVCDSAYKARI 122
                       .|...|.::....|.||..|    :.|.::.: .:.|:.:|....|..::....
plant    71 -----------HCDNSDRVDSVCNTSSSNLCTLPNQTWSWDLN-PHVSIISEWGLQCAGSFLKGF 123

  Fly   123 GQSLFFIGSVVGTLFYGLLSD-KIGRVPALILSNFCGFAGDFSTIFTKSVATFTLCRFISGLAAD 186
            ..|.||:|.::|.|....|:| .:||...|:||..........|.|:.|:..:...||::|....
plant   124 PASSFFLGCLIGGLALSTLADSSLGRKNMLLLSCLIMSLSSMLTAFSTSIWVYAFLRFLNGCGRA 188

  Fly   187 TNFYLMYIIVLEYIRPSMRTLGLNMAVGLF-YCLGLVFTPWLAVL--VGHWQIYLACTSLPILL- 247
            |......::..|.:....|  |...|:|.| :.||.:..|.|..:  ...|:.....||:|.|:
plant   189 TIGTCALVLSTELVGKKWR--GQVGAMGFFCFTLGFLSLPMLGYINEGNSWRNLYVWTSIPTLIY 251

  Fly   248 VVLYYFVVQESAQWLVTRNDIDGAIVRLKRVAKFNGCRVSQADFDEFRRHCQMTHEMLGGDDKKQ 312
            ..|....|:||.:||:.:...:.|:..|:.:|       |.|....|...|   .|:.....|..
plant   252 CCLVRSFVRESPRWLIVKGRKEEAVSILQSIA-------SNAITMSFTNLC---FEVENDQSKSN 306

  Fly   313 ATLLDMFRTPRMRKNTLILFFKSMV----ITLCYDAVSRNVEGMGISPFIMFSLSALAVLPSSVL 373
            ..:.|..:....:..:......:||    |.:.|..:...:..:..:.::....:||:..|:.::
plant   307 PDVYDALKILVRKSWSFRRLLAAMVVGFGIGMVYYGMPLALTNLNFNLYLGVVFNALSEFPAFLI 371

  Fly   374 LVLLQDRIGRKGMASGSLLVGGLFTAAAG-----IAIAYQQHNHNAILLACLTIAARFGVAISYE 433
            .....|:|.|:     ..|:|  |||.:|     ||:..||.....|:|..::.   |....::.
plant   372 TFFFIDKINRR-----DALIG--FTALSGISSALIAVLGQQLGSLQIVLELVSF---FSACTAFN 426

  Fly   434 SGSQYATELIPTCVRGQGVAAVHVAGFAASFLAPYIL--------W-LGTFFKAAPSIILGV--L 487
            ....|..|:.|||||...::.|..|.......:|.::        | .|.|     .:|:|:  |
plant   427 MTLIYTIEMFPTCVRNSAISMVRQALVFGGVFSPVMVAAGRENQFWSYGLF-----GLIIGLCGL 486

  Fly   488 FFAGSFVCLLLPETLNRSLPTTIEEGEVFGKGERMF 523
            |..|      ||||....|..|::|.|.....:|.|
plant   487 FVFG------LPETRGSVLCDTMDEEEYKTLAKRQF 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	122/532 (23%)
CG6231	NP_001262734.1	MFS	125..499	CDD:119392	92/398 (23%)
OCT3	NP_173089.1	MFS_OCT_plant	87..492	CDD:340936	98/438 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.020