DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6231 and oct2

DIOPT Version :9

Sequence 1:	NP_001262734.1	Gene:	CG6231 / 42339	FlyBaseID:	FBgn0038720	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_001107932.1	Gene:	oct2 / 797890	ZFINID:	ZDB-GENE-080204-92	Length:	554	Species:	Danio rerio

Alignment Length:	562	Identity:	149/562 - (26%)
Similarity:	259/562 - (46%)	Gaps:	56/562 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DFDQILAKCGDFNRYQFMILALFGFINIIVSMHYFTQTVISFVPDHWC-----------YHDKLV 55
            :||::|...|||..||..|..|.....::::........:.:.|||||           ..:::.
Zfish     3 NFDELLQHAGDFGFYQKRISVLGSLPILLLAFVLIGVVFLGYTPDHWCKTASLQEKCGFSEEQVR 67

  Fly    56 NMTYKEIGEIYAQFENPSCTRLDDI--NG----------HNVTVSSKACEKWIYNYDFGYRSMNT 108
            ::|....|   |:.....|.:.||.  ||          :|.|..|...|.|.:|.:  ..::.|
Zfish    68 DLTVPRTG---ARGAFSKCVKFDDALRNGSALSCNISIFNNSTHLSACNEGWTFNEN--RTTIVT 127

  Fly   109 ELNWVCDSAYKARIGQSLFFIGSVVGTLFYGLLSDKIGRVPALILSNF-CGFAGDFSTIFTKSVA 172
            |.:.||:.::.|.:.|.....|..:|.|..|.|:|:.||....|.|.| .|.:|. ..||:....
Zfish   128 EFSLVCEDSWLADLNQVSLAGGFFIGALVTGYLADRFGRKSCFIASIFGLGVSGT-CIIFSPYYP 191

  Fly   173 TFTLCRFISGLAADTNFYLMYIIVLEYIRPSMRTLGLNMAVGLFYCLGLVFTPWLAVLVGHWQIY 237
            .....|.:.|..|...:...|::::|:...:.|.. :::....||.||||..|.||..:..|:..
Zfish   192 LLLFFRCLQGFFAKGAWTATYVLIIEFFGSNNRKF-VSVMSRTFYSLGLVLLPALAYYIPSWRNL 255

  Fly   238 LACTSLPILLVVLYYFVVQESAQWLVTRNDIDGAIVRLKRVAKFNGCRVSQADFDEFRRHCQMTH 302
            ....:||..:.::|::|:.||.:||:::.....|:..:|.:||.|. |....||.|.....:...
Zfish   256 QLAMTLPTFIFLIYHWVIPESPRWLLSQRKTKEALSIVKSIAKCNK-RSLPEDFHEMDLLIEKQE 319

  Fly   303 EMLGGDDKKQATLLDMFRTPRMRKNTLILFFKSMVITLCYDAVSRNVEGMGISPFIMFSLSALAV 367
            |::      :.:..|:|:||:|||:|.||.:......:.:..:...:...|.:.|:.|.:||:..
Zfish   320 EIM------RPSYKDLFKTPKMRKHTFILIYAWFTGAVVFQGLVLRLGITGDNVFLDFLISAVVE 378

  Fly   368 LPSSVLLVLLQDRIGRKGMASGSLLVGGLFTAAAGIAIAYQQHNHNAILLACLTIAARFGVAISY 432
            ||:.::...|.|||||:.:.:....:||    ||.:|:.:...| .:.|...:.|..|..|||..
Zfish   379 LPTGLIFYFLVDRIGRRPLMATVNFIGG----AACLAVPFISPN-ISWLRRTIAIVGRLAVAIGN 438

  Fly   433 ESGSQYATELIPTCVRGQGVAAVHVAGFAASFLAPYILW-LGTFFKAAPSIILGVLFFAGSFVCL 496
            |:.:...|||.||.:|..||:....|....:.:||:||: |.:.::..|.::.||:....|.:.:
Zfish   439 ETVNFANTELYPTPLRNLGVSVCSSASDIGAVVAPFILYRLASIWQELPLLVYGVMSVLYSGLVM 503

  Fly   497 LLPETLNRSLPTTIEEGEVFGKGERMFDFPCLHNKHDDEESE 538
            ||||.....||.|::            |...|.::|..:|.:
Zfish   504 LLPEMKGVDLPETVD------------DVENLRSRHKRKEKD 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	141/522 (27%)
CG6231	NP_001262734.1	MFS	125..499	CDD:119392	104/375 (28%)
oct2	NP_001107932.1	2A0119	12..516	CDD:273328	141/522 (27%)
oct2	NP_001107932.1	MFS	123..506	CDD:119392	110/396 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588934
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.950