Protein Alignment CG6231 and Slc22a21

DIOPT Version :9

• Sequence 1: NP_001262734.1
• Gene: CG6231 / 42339
• FlyBaseID: FBgn0038720
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_062697.1
• Gene: Slc22a21 / 56517
• MGIID: 1929481
• Length: 564
• Species: Mus musculus
• Alignment Length: 579
• Identity: 138/579 - (23%)
• Similarity: 256/579 - (44%)
• Gaps: 56/579 - (9%)

  Fly     1 MDFDQILAKCGDFNRYQFMILALF-------GFINIIVSMHYFTQTVISFVPDHWCYHDKLVNMT 58
            :|:|::.|..|::..:|.:|..|.       ||..:       :...::.:|:|.|.....||::
Mouse     2 LDYDEVTAFLGEWGTFQRLIFFLLSASIIPNGFTGL-------SAVFLTAIPEHRCRIPDTVNLS 59

  Fly    59 Y--------------KEIGEIYAQFENPSCTRLDDIN---GHNVTV----SSKACEKWIYNYDFG 102
            .              .|:.:...::...:.....::.   |.:|.:    .....:.|.|:.|..
Mouse    60 SAWRNHSIPMETKDGPEVPQKCRRYRLATIANFSELGLEPGRDVDLEQLEQENCLDGWEYDKDIF 124

  Fly   103 YRSMNTELNWVCDSAYKARIGQSLFFIGSVVGTLFYGLLSDKIGRVPALILSNFCGFAGDFSTIF 167
            ..::.||.:.||...:||.:..|.|::|.::|:...|.|||:.||...|.|:........|..:|
Mouse   125 LSTIVTEWDLVCKDDWKAPLTTSFFYVGVLLGSFISGQLSDRFGRKNILFLTMAMHTGFSFIQVF 189

  Fly   168 TKSVATFTLCRFISGLAADTNFYLMYIIVLEYIRPSMRTLGLNMAVGLFYCLGLVFTPWLAVLVG 232
            :.:...|||...:.|:...:|:...:::..|.:..|:|.:...:.|.:|:..|.:..|..|..:.
Mouse   190 SVNFEMFTLLYTLVGMGHISNYVAAFVLGTEMLSKSVRIIFATLGVCIFFAFGFMVLPLFAYFIR 254

  Fly   233 HWQIYLACTSLPILLVVLYYFVVQESAQWLVTRNDIDGAIVRLKRVAKFNGCRVSQADFDEFRRH 297
            .|:..|...:||.:|....::.:.||.:||:::..|..|.|.:::.||.||.......||.
Mouse   255 EWRRLLLAITLPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDP---- 315

  Fly   298 CQMTHEMLGGDDKKQAT--LLDMFRTPRMRKNTLILFFKSMVITLCYDAVSRNVEGMGISPFIMF 360
             ..|:::.....||..:  :.|:.|||.:|..|::.....:.|::.|..:|.:...:..:.::..
Mouse   316 -SETNKLQDDSSKKPQSHHIYDLVRTPNIRILTIMSIILWLTISVGYFGLSLDTPNLNGNIYVNC 379

  Fly   361 SLSALAVLPSSVLLVLLQDRIGRKGMASGSLLVGG---LFTAAAGIAIAYQQHNHNAILLACLTI 422
            .|.|...:|:.||..||...:.|:...:|||.:||   |........:.|        |...|.:
Mouse   380 FLLAAVEVPAYVLAWLLLQHVSRRYSMAGSLFLGGSVLLLVQLVPSDLHY--------LSTTLVM 436

  Fly   423 AARFGVAISYESGSQYATELIPTCVRGQGVAAVHVAGFAASFLAPYILWLGTFFKAAPSIILGVL 487
            ..:||:..:|.....|..||.||.||..||.....|....|.|:||.::||.:.:..|.|::|.|
Mouse   437 VGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRRLPYILMGSL 501

  Fly   488 FFAGSFVCLLLPETLNRSLPTTIEEGEVFGKGERMFDFPCLHNKHDDEESESELEKYKR 546
            ....:.:.|..||:...|||.||:|.:   |.:::.....|..|...:||:..:.:..|
Mouse   502 TILTAIITLFFPESSGVSLPETIDEMQ---KVKKLKQRQSLSKKGSPKESKGNVSRTSR 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	126/530 (24%)
		MFS	125..499	CDD:119392	98/378 (26%)
Slc22a21	NP_062697.1	2A0119	12..523	CDD:273328	126/530 (24%)
		MFS	123..513	CDD:119392	104/402 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	532..564		5/26 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843881
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.950