Protein Alignment CG6231 and SLC22A17

DIOPT Version :9

• Sequence 1: NP_001262734.1
• Gene: CG6231 / 42339
• FlyBaseID: FBgn0038720
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_065105.3
• Gene: SLC22A17 / 51310
• HGNCID: 23095
• Length: 649
• Species: Homo sapiens
• Alignment Length: 613
• Identity: 155/613 - (25%)
• Similarity: 236/613 - (38%)
• Gaps: 167/613 - (27%)

  Fly     1 MDFDQILAKCGDFNRYQFMILALFGFINIIVSMHYFTQTVISFVPDHWCYHDKLVNMTYKEIGEI 65
            :.|:.:||:.|.....|.:.|.|.....:.|::...:..:.:..|...|:        |......
Human    78 LSFEALLAQVGALGGGQQLQLGLCCLPVLFVALGMASDPIFTLAPPLHCH--------YGAFPPN 134

  Fly    66 YAQFENPSCTRLDDINGHNVTVSSKA---------------------------CEK-WIYNYDFG 102
            .:.:|.|.       |...|:|:|.|                           |.| |.||   |
Human   135 ASGWEQPP-------NASGVSVASAALAASAASRVATSTDPSCSGFAPPDFNHCLKDWDYN---G 189

  Fly   103 YRSMNTEL--NW--VCDSAYKARIGQSLFFIGSVVGTLFYGLLSDKIGRVPALILS----NFCGF 159
            ...:.|..  .|  |||..::..:.|.||.:|...|.||.|..:|:.||...::|:    ..||.
Human   190 LPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRGIVLLTLGLVGPCGV 254

  Fly   160 AGDFSTIFTKSVATFTLCRFISGL---AADTNFYLMYIIVLEYIRPSMRTLGLNMAV-------- 213
            .|..:...|..:|    .||:.|.   ..|...|||.   ||...|:.|   |.:|:
Human   255 GGAAAGSSTGVMA----LRFLLGFLLAGVDLGVYLMR---LELCDPTQR---LRVALAGELVGVG 309

  Fly   214 GLFYCLGLVFTPWLAVLVGHWQIYLACTSLPILLVVLYYF--VVQESAQWLVTRNDIDGAIVRLK 276
            |.|..||      ||::...|:......:.|.:|.:.|.:  :..|||:||:.:..|:.|...|:
Human   310 GHFLFLG------LALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLR 368

  Fly   277 RVAKFNGCRVSQADFDEFRRHCQMTHEMLGGDDKKQATLLDMFRT-----------------PRM 324
            .:|:.|            |.|.|    |||  ::.|..|.|:..|                 ..:
Human   369 ILAERN------------RPHGQ----MLG--EEAQEALQDLENTCPLPATSSFSFASLLNYRNI 415

  Fly   325 RKNTLILFFKSMV---ITLCYDAVSRNVEGMGISP--FIMFSL--SALAVLPSSVLLVLLQDRIG 382
            .||.|||.|.:.:   |..||..|     |.|.||  |.:.||  |..|.| :.|.|.:..||.|
Human   416 WKNLLILGFTNFIAHAIRHCYQPV-----GGGGSPSDFYLCSLLASGTAAL-ACVFLGVTVDRFG 474

  Fly   383 RKGM--------ASGSLLVGGLFTAAAGI--AIAYQQHNHNAIL-LACLTIAARFGVAISYES-- 434
            |:|:        ...||::.||:.....|  .:..||.|.|..| .|.:|..:..|:..|..:
Human   475 RRGILLLSMTLTGIASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGLFSSQAAAI 539

  Fly   435 -GSQYATELIPTCVRGQGVAAVHVAGFAASFLAPYILWLGTFFKAAPSIILG-------VLFFAG 491
             .:..|.|:|||.|||:|:..:...|.......|           |..:.:|       |:..|.
Human   540 LSTLLAAEVIPTTVRGRGLGLIMALGALGGLSGP-----------AQRLHMGHGAFLQHVVLAAC 593

  Fly   492 SFVC----LLLPETLNRSLPTTIEEGEV 515
            :.:|    :|||||..:.||..:.:||:
Human   594 ALLCILSIMLLPETKRKLLPEVLRDGEL 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	150/595 (25%)
		MFS	125..499	CDD:119392	117/439 (27%)
SLC22A17	NP_065105.3	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153311
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.030