DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6231 and CG6356

DIOPT Version :9

Sequence 1:	NP_001262734.1	Gene:	CG6231 / 42339	FlyBaseID:	FBgn0038720	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_651240.1	Gene:	CG6356 / 42893	FlyBaseID:	FBgn0039178	Length:	570	Species:	Drosophila melanogaster

Alignment Length:	546	Identity:	119/546 - (21%)
Similarity:	213/546 - (39%)	Gaps:	100/546 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 NIIVSMHYFTQTVISFVP-DHWCYHDKL--VNMTYKEIGEIYAQ-FENPSCTRLDDINGHNVTVS 88
            ||:...|..:.|::..:| |.||...:|  .|.|:.:..||.|: .::..||..|...||...:|
  Fly    49 NILNGFHVSSYTLLGHLPDDQWCGIPELQDTNWTHAQKREIVAKGLDSGGCTVWDWNYGHLAKMS 113

  Fly    89 SKACEKWIYNY---------------------DFGYRSMNTELNW--VCDSAYKARIGQSLFFIG 130
            .:|.    .||                     :|.:.......:|  .||.:.:....|....:|
  Fly   114 YEAA----LNYTGHLTQISPPAEVSCRVKGQHEFAHPETTFVADWDLTCDRSIQRTSAQVSISLG 174

  Fly   131 SVVGTLFYGLLSDKIGRVPALILSNFCGFAGDFSTIFTKSVATFTLCRFISGLAADTNFYLMYII 195
            ...|:..:|:|:||.||..:..|.......|.|...|:...:.|...||..|.|:...||..:.:
  Fly   175 KFCGSFSFGILADKFGRKSSFTLGAAFFIVGSFFCTFSPWYSLFLAGRFALGAASSGLFYPAFTM 239

  Fly   196 VLEYIRPSMRTLGLNMAVGLFYCLGLVFTPWLAVLVGHWQIYLACTSLPILLVVLYYFVVQESAQ 260
            ::|.|....|: .:::|....|.:|::....:..::..|:......::|.||::|..:::.||.:
  Fly   240 IVENICLKHRS-WMSIAFSASYPVGMIILAIVGYVIQPWRHLQLALTIPSLLLILNCYLMSESPR 303

  Fly   261 WLVTRNDIDGAIVRLKRVAKFNGCRVSQADFDEFRR--HCQMTHEMLG----GDDKKQ------- 312
            ||:|..       |..||.|.           .||:  |.|:...:..    ..|||.
  Fly   304 WLITNQ-------RYDRVYKI-----------LFRQPSHYQIQPAVAAPSQVASDKKSLEPEEGF 350

  Fly   313 -----------ATLLDMFRTPRMRKNTLILFFKSMVITLCYDAVSRNVEGMGISPFIMFSLSALA 366
                       .::::::...::|:.....:|...|.:|.|...:.|...:.:|.::....:.|.
  Fly   351 SFGQKLKNGPLKSIIELYANSKVRRMIFASYFMFCVTSLSYYVTALNAANLSVSRYLYIIGTGLV 415

  Fly   367 VLPSSVLLVLLQDRIGRK----------GMASGSLLVGGLFTAAAGIAIAYQQHNHNAILLACLT 421
            .:||.::.|::....||:          |:   |||:  :....||          :...:....
  Fly   416 DIPSYLVPVIMLRFTGRRLTTMFLFLWTGV---SLLL--VLAVPAG----------STTWIVAFA 465

  Fly   422 IAARFGVAISYESGSQYATELIPTCVRGQGVAAVHVAGFAASFLAPYIL-WLGTFFKAAPSIILG 485
            :..|||::.:|...:.|..||.||.:|...:..........|..|||:: .||......|:.|.|
  Fly   466 MLGRFGISATYSVVTLYTAELYPTQIRNSALGTCSTFAHVGSISAPYVVDVLGALGWYIPTTICG 530

  Fly   486 VLFFAGSFVCLLLPETLNRSLPTTIE 511
            ........:.|.||||....|...:|
  Fly   531 CCVLVAGLLTLTLPETGTGKLSDKVE 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	118/542 (22%)
CG6231	NP_001262734.1	MFS	125..499	CDD:119392	85/408 (21%)
CG6356	NP_651240.1	MFS	167..544	CDD:119392	86/410 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458477
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	6	5.990