DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6231 and CG7084

DIOPT Version :9

Sequence 1:	NP_001262734.1	Gene:	CG6231 / 42339	FlyBaseID:	FBgn0038720	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_001247235.2	Gene:	CG7084 / 42606	FlyBaseID:	FBgn0038938	Length:	597	Species:	Drosophila melanogaster

Alignment Length:	604	Identity:	166/604 - (27%)
Similarity:	264/604 - (43%)	Gaps:	99/604 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 FDQILAKCGDFNRYQFMI-------LALFG---FINIIVSMHYFTQTVISFVPDHWC-------- 49
            |..::.|.|:..|||.:.       ||..|   ::|||::::         :|||||
  Fly    34 FQALMEKAGNHGRYQTLYNFVFVGGLAFSGAMIYMNIILALN---------IPDHWCTVPGRENT 89

  Fly    50 ------YHD------------------KLVNMTYKEIGEIYAQFENPSCTRLDDINGHNVTVSSK 90
                  :.|                  ::..|.:.||.:..|.             ..|:|.:::
  Fly    90 NFSLEEWRDITLPKQADNRGRKTFSNCEMFQMNFSEITDWSAW-------------NSNLTKTTE 141

  Fly    91 ACEK-WIYNYDFGYRSMNTELNWVCDSAYKARIGQSLFFIG---SVVGTLFYGLLSDKIGRVPAL 151
            ||:. |.|:..:...::.|:.||||   .|.....::|.:|   .|.|:...|.:.|..||....
  Fly   142 ACQNGWSYDKTWYESTIPTDHNWVC---AKDLFVTNVFVVGRVTEVAGSFILGQMGDSYGRRFVY 203

  Fly   152 ILS-NFCGFAGDFSTIFTKSVATFTLCRFISGLAADTNFYLMYIIVLEYIRPSMRT-LGLNMAVG 214
            .:| .||......|.:.|.|...|.:...|.||..::.|....||.:|..|...|: :....:.|
  Fly   204 YISVVFCSLGRLGSIMCTSSYTWFLIMSGIVGLTVNSLFQSPQIIGMEISREEDRSRIAFFQSCG 268

  Fly   215 LFYCLGLVFTPWLAVLVGHWQIYLACTSLPILLVVLYYFVVQESAQWLVTRNDIDGAIVRLKRVA 279
              :.:|....|.|...:.||..::..||:|..:|:|:...|.||.:||:::.....|||:|:::|
  Fly   269 --WSIGTTLMPLLYWWLRHWDSFMWLTSIPTAMVLLFSKYVIESPRWLISKQRFREAIVQLQKIA 331

  Fly   280 KFNGCRVSQADFDEFRRHCQMTHEMLG---GDDKKQAT--LLDMFRTPRMRKNTLILFFKSMVIT 339
            |.||.|     ||       ||.:.|.   ..||:..|  :..:|...|:.:||.|:.|...|:.
  Fly   332 KINGHR-----FD-------MTEKELAEIYSRDKQDVTYGIASLFAGWRLARNTTIMGFSWCVVA 384

  Fly   340 LCYDAVSRNVEGMGISPFIMFSLSALAVLPSSVLLVLLQDRIGRKGMASGSLLVGGLFTAAAGIA 404
            :.|..:......|..:||:.|...::..:|:.|:...:.|..||:...|.|.|:.  |.....|
  Fly   385 VSYFTLVLFSSRMAGNPFLNFLYQSIVEIPAYVVGRYMGDTYGRRFTNSVSFLIS--FVTCLPI- 446

  Fly   405 IAYQQHNHNAILLACLTIAARFGVAISYESGSQYATELIPTCVRGQGVAAVHVAGFAASFLAPYI 469
            |.|........|:..|....:|..|:::.:.:....|:.|||:|..|||...:...|...||||:
  Fly   447 IVYSTDERYENLMIYLATFIKFLNALTFFTVNLQCLEIYPTCMRQTGVALGTILANAIGVLAPYL 511

  Fly   470 LWLGTFFK-AAPSIILGVLFFAGSFVCLLLPETLNRSLPTTIEEGEVFGKGERMFDF---PCLHN 530
            ::|||... .||..||||||..|....|.|||||::.||.|:||...|||.::.|..   |....
  Fly   512 VYLGTTVDIRAPYYILGVLFLLGGIGALFLPETLHKKLPDTMEEAGHFGKHDKFFSLPKPPQAAE 576

  Fly   531 KHDDEESESELEKYKRKHS 549
            |.|...|..||.:.:|..:
  Fly   577 KDDKLSSHPELTRLRRSET 595

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	150/551 (27%)
CG6231	NP_001262734.1	MFS	125..499	CDD:119392	111/384 (29%)
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	143/529 (27%)
CG7084	NP_001247235.2	MFS	184..542	CDD:119392	109/374 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	5	5.060