Protein Alignment CG6231 and SLC22A

DIOPT Version :9

• Sequence 1: NP_001262734.1
• Gene: CG6231 / 42339
• FlyBaseID: FBgn0038720
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Alignment Length: 560
• Identity: 128/560 - (22%)
• Similarity: 236/560 - (42%)
• Gaps: 85/560 - (15%)

  Fly     4 DQILAKCGDFNRYQ---FMILALFGFINIIVSMHY-FTQTVISFVPDHWC-----------YHDK 53
            |.||...|.|.|:|   |:::.|....:.:.|:.| ||...::    |.|           |::.
  Fly    28 DAILKHLGQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATVT----HRCSVEECDLPGSNYYEP 88

  Fly    54 LVNMTYKEIGEIYAQFENPSCTR------------LDDINGHNVTVSSKACEKWIYNYDFGYR-- 104
            ..|.:..:.|:     :..||.|            :|..:..:.|.:.:||.    :.:|.:|
  Fly    89 HTNWSIPKNGK-----DLDSCNRYTNSELPQWNHSVDICSADHFTKNKEACA----HNEFVFRDD 144

  Fly   105 --SMNTELNWVCDSAYKARIGQSLFFIGSVVGTLFYGLLSDKIGRVPALILSNFCGFAGDFSTIF 167
              :::.:....||..:|..:..::..:|...|....|.::|:.||..::.|....|........|
  Fly   145 EVTISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIGGFVADRYGRSFSIALGGILGAVLGVIRSF 209

  Fly   168 TKSVATFTLCRFISGLAADTNFYLMYIIVLEYIRPSMRTLGLNMAVGLFYCLGLVFTPWLAVLVG 232
            :.|...|.:..|:..:.:.|.:...::|.:|.:.|..|.|..:: :.:||.:|.|.....|....
  Fly   210 SPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSV-ITVFYAVGEVLLAMSAKAFH 273

  Fly   233 HWQIYLACTSLPILLVVLYYFVVQESAQWLVTRNDIDGAIVRLKRVAKFNGCRVSQADFDEFRRH 297
            .|:|.|..|..|.|:::.|::::.||.:||:::...:.|...|:|.|..|...:.::..|:.
  Fly   274 DWRILLRITYGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKRELPESVLDKL--- 335

  Fly   298 CQMTHEMLGGDDKKQATLLDMFRTPRMRKNTLILFFKSMV--ITLC-------YDAVSRNVEGMG 353
                  :|...||.|.:....|......||     ||..:  .:||       |..:|.||..:.
  Fly   336 ------VLANRDKLQQSSESRFPIREAFKN-----FKWRIANCSLCWIVHVLVYYGLSLNVVLLD 389

  Fly   354 ISPFIMFSLSALAVLPSSVLLVLLQDRIGRK------GMASGSLLVGGLFTAAAGIAIAYQQHNH 412
            ...:..|:..||..:|...:.:|:.||.||:      .:|||...:|.:||.|           .
  Fly   390 GDKYNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGTIFTGA-----------D 443

  Fly   413 NAILLACLTIAARFGVAISYESGSQYATELIPTCVRGQGVAAVHVAGFAASFLAPYILWLGTFFK 477
            ..:|...|.:..:..:..|::....:|:|:.||.:|...::...:.|...|.|||....|..::.
  Fly   444 QPVLQLVLFLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYA 508

  Fly   478 AAPSIILGVLFFAGSFVCLLLPETLNRSLPTTIEEGEVFG 517
            .||:::..........:.|..|||.|..||||::|.:..|
  Fly   509 NAPAMLFAGAAIVSGLLTLFFPETTNVVLPTTVQEADAIG 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	121/543 (22%)
		MFS	125..499	CDD:119392	88/388 (23%)
SLC22A	NP_649370.1	2A0119	35..540	CDD:273328	121/543 (22%)
		MFS	146..530	CDD:119392	91/409 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458502
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.990