Protein Alignment CG6231 and SLC22A10

DIOPT Version :9

• Sequence 1: NP_001262734.1
• Gene: CG6231 / 42339
• FlyBaseID: FBgn0038720
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_001034841.3
• Gene: SLC22A10 / 387775
• HGNCID: 18057
• Length: 541
• Species: Homo sapiens
• Alignment Length: 558
• Identity: 140/558 - (25%)
• Similarity: 242/558 - (43%)
• Gaps: 71/558 - (12%)

  Fly     1 MDFDQILAKCGDFNRYQFMILALFGFINIIVSMHYFTQTVISFVPDHWCYHDKLVNMT--YKEIG 63
            |.|:::|::.|...|:|.:.|.......:::..|...:...:.:|.|.|:...|.|.|  ..|.|
Human     1 MAFEELLSQVGGLGRFQMLHLVFILPSLMLLIPHILLENFAAAIPGHRCWVHMLDNNTGSGNETG 65

  Fly    64 --------------------EIYAQFENPSCTRLDDING--HNVT-VSSKAC-EKWIYNYDFGYR 104
                                |...:|.:|. .:|..:||  |:.: ..::.| :.|:|:..:...
Human    66 ILSEDALLRISIPLDSNLRPEKCRRFVHPQ-WQLLHLNGTIHSTSEADTEPCVDGWVYDQSYFPS 129

  Fly   105 SMNTELNWVCDSAYKARIGQSLFFIGSVVGTLFYGLLSDKIGR-------VPALILSNFCGFAGD 162
            ::.|:.:.|||......:.|.|...|.:||.:..|.:||:.||       :..|.:::.|
Human   130 TIVTKWDLVCDYQSLKSVVQFLLLTGMLVGGIIGGHVSDRFGRRFILRWCLLQLAITDTC----- 189

  Fly   163 FSTIFTKSVATFTLCRFISGLAADTNFYLMYII------VLEYIRPSMRTLGLNMAVGLFYCLGL 221
              ..|..:...:.:.||::|      |..|.||      :.|:|||:.:.|.:.::.|.. .:|.
Human   190 --AAFAPTFPVYCVLRFLAG------FSSMIIISNNSLPITEWIRPNSKALVVILSSGAL-SIGQ 245

  Fly   222 VFTPWLAVLVGHWQIYLACTSLPILLVVLYYFVVQESAQWLVTRNDIDGAIVRLKRVAKFNGCRV 286
            :....||.:...||......|:|..:..|....:.|||:||:..|.:|..:..|::||:.||.:.
Human   246 IILGGLAYVFRDWQTLHVVASVPFFVFFLLSRWLVESARWLIITNKLDEGLKALRKVARTNGIKN 310

  Fly   287 SQADFDEFRRHCQMTHEMLGGDDKKQATLLDMFRTPRMRKNTLILFFKSMVITLCYDAVSRNVEG 351
            ::...:.......|..|:.....|  .|:.|:||.|.|||...||.|.....|:.:.....|::.
Human   311 AEETLNIEVVRSTMQEELDAAQTK--TTVCDLFRNPSMRKRICILVFLRFANTIPFYGTMVNLQH 373

  Fly   352 MGISPFIMFSLSALAVLPSSVLLVLLQDRIGRKGMASGSLLVGGLFTAAAGIAI-----AYQQHN 411
            :|.:.|::..|.....|....|.:|..:.:||:       :...||....|::|     ..::..
Human   374 VGSNIFLLQVLYGAVALIVRCLALLTLNHMGRR-------ISQILFMFLVGLSILANTFVPKEMQ 431

  Fly   412 HNAILLACLTIAARFGVAISYESGSQYATELIPTCVRGQGVAAVHVAGFAASFLAPYILWLGTFF 476
            ...:.||||.|...   |.::.|.:.:..|||||.:|.:.......|....:.|||.::.|..||
Human   432 TLRVALACLGIGCS---AATFSSVAVHFIELIPTVLRARASGIDLTASRIGAALAPLLMTLTVFF 493

  Fly   477 KAAPSIILGVLFFAGSFVCLLLPETLNRSLPTTIEEGE 514
            ...|.||.|:....|..:..|||||.|..||.||::.|
Human   494 TTLPWIIYGIFPIIGGLIVFLLPETKNLPLPDTIKDVE 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	134/541 (25%)
		MFS	125..499	CDD:119392	99/391 (25%)
SLC22A10	NP_001034841.3	2A0119	11..526	CDD:273328	134/541 (25%)
		MFS	143..516	CDD:119392	100/398 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153696
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.940