Protein Alignment CG6231 and Slc22a20

DIOPT Version :10

• Sequence 1: NP_650819.1
• Gene: CG6231 / 42339
• FlyBaseID: FBgn0038720
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_941052.1
• Gene: Slc22a20 / 381203
• MGIID: 2685809
• Length: 556
• Species: Mus musculus
• Alignment Length: 571
• Identity: 133/571 - (23%)
• Similarity: 234/571 - (40%)
• Gaps: 59/571 - (10%)

  Fly     1 MDFDQILAKCGDFNRYQFMILALFGFINIIVSMHYFTQTVISFVPDHWCYHDKLVNMTYKEIGEI 65
            |.|..:|...|...|:|.:..||......:::.|.|.|...:..|.|.|.|..........:..:
Mouse     1 MAFTDLLDALGGVGRFQLVYTALLLLPCGLLACHTFLQNFTAAAPPHHCQHPANYTEPTTNVSGV 65

  Fly    66 YAQFENP--------SCTR-------LDDINGHNVTVSSKAC-EKWIYNYDFGYRSMNTELNWVC 114
            :.:...|        .|.|       |...|..:..|:::.| :.|:|:......::..|.:.||
Mouse    66 WLRAAIPLNQHGDPEPCRRYVEPQWALLKPNASSHGVATEGCKDGWVYDRSIFPSTIVMEWDLVC 130

  Fly   115 DSAYKARIGQSLFFIGSVVGTLFYGLLSDKIGRVPALILSNFCGFAGDFSTIFTKSVATFTLCRF 179
            ::.....:.||::..|.:||...:|.|:|::||...|:.|.........:|.:..|.:.:.:.||
Mouse   131 EARTLRDLAQSIYMSGVLVGAALFGGLADRLGRKAPLVWSYLQLAVSGAATAYVGSFSAYCVFRF 195

  Fly   180 ISGLAADTNFYLMYIIVLEYIRPSMRTLGLNMAVGLFYCLGLVFTPWLAVLVGHWQIYLACTSLP 244
            :.|:...........:|:|::....||:. .:.:|..:.||.:....:|.|:..|:......|.|
Mouse   196 LMGMTFSGIILNSLSLVVEWMPTRGRTVA-GILLGFSFTLGQLILAGVAYLIRPWRWLQFAVSAP 259

  Fly   245 ILLVVLYYFVVQESAQWLVTRNDIDGAIVRLKRVAKFNGCR----------VSQADFDEFRRHCQ 299
            .|:..||.:.:.||::||:.......|:..|::||..||.:          ||....|||
Mouse   260 FLVFFLYSWWLPESSRWLLLHGKAQQAVQNLQKVAMMNGRKAEGERLTTEVVSSYIQDEF----- 319

  Fly   300 MTHEMLGGDDKKQATLLDMFRTPRMRKNTLILFFKSMVITLCYDAVSRNVEGMGISPFIMFSLSA 364
                   ...:...::||:||||.:|:.|..|.......::.|..::.:::..|:|.:::.:|..
Mouse   320 -------ASVRTSNSILDLFRTPAIRRVTCCLMGVWFSNSVAYYGLAMDLQKFGLSIYLVQALFG 377

  Fly   365 LAVLPSSVLLVLLQDRIGRKGMASGSLLVGGLFTAAAGIAIAYQQHNHNAILLACLTIAARFG-- 427
            :..:|:.::.......:||:...|..|::.||..    ||..:...:    |....|:.|..|
Mouse   378 IIDIPAMLVATTTMIYVGRRATVSSFLILAGLMV----IANMFMPED----LQTLRTVQAALGKG 434

  Fly   428 -VAISYESGSQYATELIPTCVRGQGVAAVHVAGFAASFLAPYILWLGTFFKAAPSIILGVL-FFA 490
             :|.|:.....:..||.||.:|..|:....|.......:||.|..||......|.:..|.. ..|
Mouse   435 CLASSFICVYLFTGELYPTEIRQMGMGFASVNARLGGLVAPLITTLGEISPVLPPVSFGATSVLA 499

  Fly   491 GSFVCLLLPETLNRSLPTTIEEGEVFGKGERMFDFPCLHNKHDDEESESEL 541
            |..|...|.||.|..|..||...|...|..|        :|.|.|:...|:
Mouse   500 GMAVACFLTETRNVPLVETIAAMERRVKQGR--------SKRDTEQKSEEI 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_650819.1	2A0119	11..509	CDD:273328	121/527 (23%)
Slc22a20	NP_941052.1	MFS_SLC22A6_OAT1_like	103..508	CDD:341004	98/425 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	526..556		6/25 (24%)