Protein Alignment CG6231 and Slc22a12

DIOPT Version :10

• Sequence 1: NP_650819.1
• Gene: CG6231 / 42339
• FlyBaseID: FBgn0038720
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: XP_063125948.1
• Gene: Slc22a12 / 365398
• RGDID: 621628
• Length: 643
• Species: Rattus norvegicus
• Alignment Length: 525
• Identity: 137/525 - (26%)
• Similarity: 228/525 - (43%)
• Gaps: 95/525 - (18%)

  Fly    44 VPDHWCYHDKLVNMTYK-----EIGE--IYA---------------QFENPSCTRLDDINGHNVT 86
            ||.|.|:...|.|.|.:     :.|.  :.|               :|..|....::.    |.|
  Rat   134 VPHHRCWVPLLDNSTSQASIPGDFGRDVLLAVSIPPGPDQRPHQCLRFRQPQWQLIES----NTT 194

  Fly    87 VS------SKACEK-WIYNYDFGYRSMNTELNWVCDSAYKARIGQSLFFIGSVVGTLFYGLLSDK 144
            .:      ::.||. |:|::.....::.|..:.||||.....:.||:|..|.:||....|..||:
  Rat   195 ATNWSDADTEPCEDGWVYDHSTFRSTIVTTWDLVCDSQALRPMAQSIFLAGILVGAAVCGHASDR 259

  Fly   145 IGRVPALILSN-FCGFAGDFSTIFTKSVATFTL-CRF-------ISGLAADTNFYLMYIIVLEYI 200
            .||...|..|. ....:|..:.:    :.||.| |.|       ::|:..:|...||     |:.
  Rat   260 FGRRRVLTWSYLLVSVSGTIAAL----MPTFPLYCLFRFLVASAVAGVMMNTASLLM-----EWT 315

  Fly   201 R----PSMRTLGLNMAVGLFYCLGLVFTPWLAVLVGHWQIYLACTSLPILLVVLYYFVVQESAQW 261
            .    |.|.||.   |:|  :..|.|.|..:|..|..|::.....|.|..|..:|.:.:.|||:|
  Rat   316 SAQAGPLMMTLN---ALG--FSFGQVLTGSVAYGVRSWRMLQLAVSAPFFLFFVYSWWLPESARW 375

  Fly   262 LVTRNDIDGAIVRLKRVAKFNGCRVSQADFDEFRRHCQMTHEMLGGDDKKQ-------ATLLDMF 319
            |:|...:|.::..|:|||..|. |.::||        .:|.|:|....:::       |.|..:.
  Rat   376 LITVGRLDQSLRELQRVAAVNR-RKAEAD--------TLTVEVLRSAMQEEPNGNQAGARLGTLL 431

  Fly   320 RTPRMRKNTLILFFKSMVITLCYDA-------VSRNVEGMGISPFIMFSLSALAVLPSSVLLVLL 377
            .||.:|..|.|    ||   ||:.|       ::.:::.:|.:.|::.:|..:..||..:..:||
  Rat   432 HTPGLRLRTFI----SM---LCWFAFGFTFYGLALDLQALGSNIFLLQALIGIVDLPVKMGSLLL 489

  Fly   378 QDRIGRKGMASGSLLVGGLFTAAAGIAIAYQQHNHNAILLACLTIAARFGVAISYESGSQYATEL 442
            ..|:||:...:.||::.|| ...|.|.:..:.    .||.:.|.:.....:..::...:.:::||
  Rat   490 LSRLGRRLCQASSLVLPGL-CILANILVPREM----GILRSSLAVLGLGSLGAAFTCVTIFSSEL 549

  Fly   443 IPTCVRGQGVAAVHVAGFAASFLAPYILWLGTFFKAAPSIILGVLFFAGSFVCLLLPETLNRSLP 507
            .||.:|...|....||....:.|.|.:..||.:....|.::.||:........||||||.|..||
  Rat   550 FPTVIRMTAVGLGQVAARGGAMLGPLVRLLGVYGSWLPLLVYGVVPVLSGLAALLLPETKNLPLP 614

  Fly   508 TTIEE 512
            .||::
  Rat   615 DTIQD 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_650819.1	2A0119	11..509	CDD:273328	135/520 (26%)
Slc22a12	XP_063125948.1	None