DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6231 and Balat

DIOPT Version :9

Sequence 1:	NP_001262734.1	Gene:	CG6231 / 42339	FlyBaseID:	FBgn0038720	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_610823.1	Gene:	Balat / 36417	FlyBaseID:	FBgn0033778	Length:	604	Species:	Drosophila melanogaster

Alignment Length:	563	Identity:	153/563 - (27%)
Similarity:	245/563 - (43%)	Gaps:	73/563 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDFDQILAKCGDFNRYQFMILALFGFINIIV------SMHYFTQTVISFVPDHWC---------- 49
            ||||::|.:.|.|..||.:|:.     ::::      :.|.::|..|:..|.|:|
  Fly     1 MDFDEVLREVGSFGLYQKVIIC-----SVLLPAALPCAFHAYSQLFIAATPQHFCRVPELEPWTQ 60

  Fly    50 -YHDKLVNMT------------------YKEIGEIYAQFENPSCTRL---DDINGHNVTVSSKAC 92
             |...:.|::                  |.:|.........|...|.   |.:.....|.....|
  Fly    61 DYVQLVKNLSIPRNRNGAYAECSMYSRNYTDIVRYLEYRPPPDLLRQQAEDLLKLQPDTTQVVPC 125

  Fly    93 EK-WIYNYDFGYRSMNTELNWVCDSAYKARIGQSLFFIGSVVGTLFYGLLSDKIGRVP---ALIL 153
            :. |.|:......::..|.|.|||.::...:...:|.:|.::|...:|.|.|..||.|   |.:|
  Fly   126 QHGWHYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLWGRRPSFYAYLL 190

  Fly   154 SNFCGFAGDFSTIFTKSVATFTLCRFISGLAADTNFYLMYIIVLEYIRPSMR---TLGLNMAVGL 215
            ......|   ::.|..:..|:...||:.||.........|::.:|.:.|..|   |:..|:|
  Fly   191 LEIIACA---ASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPERRVFCTIVSNIA--- 249

  Fly   216 FYCLGLVFTPWLAVLVGHWQIYLACTSLPILLVVLYYFVVQESAQWLVTRNDIDGAIVRLKRVAK 280
             |.||||....:..:|..|:......|:|:|::...:||:.||.:||:.......||..||.:|:
  Fly   250 -YSLGLVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILKVMAR 313

  Fly   281 FNGCRVSQADFDEFRRHCQMTHEMLGGDDKKQAT----LLDMFRTPRMRKNTLILFFKSMVITLC 341
            .||.||::...:..:|...:|.   ..:.|...|    :||:||.|.||:.|||:.......|..
  Fly   314 VNGVRVNRDFVERLQRKLVITR---AAETKSSMTTHYGILDLFRGPNMRRKTLIITLIWFANTSV 375

  Fly   342 YDAVSRNVEGMGISPFIMFSLSALAVLPSSVLLVLLQDRIGRKGMASGSLLVGGLFTAAAGIAIA 406
            |..:|.....:|......|.|:....||:.:||.......||:.:...|:||||:...|..:
  Fly   376 YVGLSYYAPALGGDEIWNFFLAGAVELPTYLLLWPGLSYFGRRWILFISMLVGGVACVATFL--- 437

  Fly   407 YQQHNHNAILLACLTIAARFGVAISYESGSQYATELIPTCVRGQGVAAVHVAGFAASFLAPYILW 471
               :....:||.|:   .:.|::.|:......|:||.||.|||.|::...|.......:.|.|..
  Fly   438 ---YPDITLLLYCV---GKMGISSSFVVLPLMASELYPTVVRGLGMSFSSVISMVGPIVIPMINH 496

  Fly   472 LGTFFKAAPSIILGVLFFAGSFVCLLLPETLNRSLPTTIEEGE 514
            :|......|.|::|.|...|.|..||||||.||:||.|:||||
  Fly   497 MGQQMLVLPLIVMGALLILGGFASLLLPETRNRNLPQTLEEGE 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	143/546 (26%)
CG6231	NP_001262734.1	MFS	125..499	CDD:119392	108/383 (28%)
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	115/414 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458529
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	6	5.990