Protein Alignment CG6231 and Slc22a15

DIOPT Version :10

• Sequence 1: NP_650819.1
• Gene: CG6231 / 42339
• FlyBaseID: FBgn0038720
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_001101177.1
• Gene: Slc22a15 / 310732
• RGDID: 1311184
• Length: 548
• Species: Rattus norvegicus
• Alignment Length: 610
• Identity: 144/610 - (23%)
• Similarity: 247/610 - (40%)
• Gaps: 91/610 - (14%)

  Fly     1 MDFDQILAKCGDFNRYQFMILALFGFINIIVSMHYFTQTV----ISFVPD-HWCYHDKLVNMTYK 60
            |:.::.....|:...||..:..|   :.:::.::..|:.:    |...|. ||...:.|.|.::
  Rat     1 MEVEEAFQAVGEMGLYQMYLCFL---LAVLLQLYVATEAILIALIGATPAYHWDMAELLPNQSH- 61

  Fly    61 EIGEIYAQFENPSCTRLDDINGHNVTVSSKACEKWIYNYDFGYRSMNTELNWVCDSAYKARIGQS 125
                     .|.|..:........:|.:.....|.:: :...:.|:.:|...:.:.:||.....|
  Rat    62 ---------SNQSSGKGQAFGDWLLTANGSEIHKHVH-FSNSFTSIASEWFLIANRSYKVSAASS 116

  Fly   126 LFFIGSVVGTLFYGLLSDKIGRVPALILSNFCGFAGD----FSTIFTKSVATFTLCRFISGLAAD 186
            .||.|..||.:.:|.|||:.||....:    .|||.|    .:..|:.|...|.:.||:.|:...
  Rat   117 FFFSGVFVGVISFGQLSDRFGRKKVYL----TGFALDILFAIANGFSPSYEFFAVTRFLVGMMNG 177

  Fly   187 TNFYLMYIIVLEYIRPSMRTLGLNMAVGLFYCLGLVFTPWLAVLVGHWQIYLACTSLPILLVVLY 251
            ....:.::::.|.:..:...|..::. |||:.:|:.....|...:..|:......:|...:|.|.
  Rat   178 GMSLVAFVLLNECVGAAYWALAGSIG-GLFFAVGIAQYALLGYFIRSWRTLAILVNLQGTVVFLL 241

  Fly   252 YFVVQESAQWLVTRNDIDGAIVRLKRVAKFNGCRVSQADFDEFRRHCQMTHEMLGGDDKKQATLL 316
            ...:.||.:||.::..:..|...|..:||.|  |..:..|       .:||. .....::..:.|
  Rat   242 SLFIPESPRWLYSQGRLSEAEEALYLIAKRN--RKLKCTF-------SLTHP-ANRSYRETGSFL 296

  Fly   317 DMFRTPRMRKNTLILFFKSMVITLCYDAVSRNVEGMGISPFIMFSLSALAVLPSSVLLVLL--QD 379
            |:||...:..:||||.|...|.:|.|..::.:...:|.|.:...:||.|..:||..|.:.|  |.
  Rat   297 DLFRYRVLLGHTLILMFIWFVCSLVYYGLTLSAGDLGGSIYANLALSGLIEIPSYPLCIYLINQR 361

  Fly   380 RIGRKGMASGSLLVGGLFTAAAGIAIAYQQ----------HNHNAILLACLTIAARFGVAISYES 434
            ..|||...:..|.:|||   |..|.:...:          ::|:..||..|||:|.|.:...|.|
  Rat   362 WFGRKRTLAAFLCLGGL---ACLIVMFLPEKKDTGVFAVVNSHSLSLLGKLTISAAFNIVYIYTS 423

  Fly   435 GSQYATELIPTCVRGQGVAAVHVAGFAASFLAPYILWLGTFFKAAPSIILGVLFFAGSFVCLLLP 499
                  ||.||.:|..|:....:.......:||::..|.....:.|.|:.|........:.||||
  Rat   424 ------ELYPTVIRNVGLGTCSMFSRVGGIIAPFVPSLKDVQWSLPFIVFGATGLTSGLLSLLLP 482

  Fly   500 ETLNRSLPTTIEEGEVFG---KGE-----RMFDFPCLHNKHDDEESESELEKYKRKHSLIDAKQM 556
            ||||..|..|..:.:::.   .||     :..|.|....|.....||||.|
  Rat   483 ETLNSPLLETFSDLQMYSYRRLGEEALSLQTLDPPQPLGKASSLGSESEEE-------------- 533

  Fly   557 QMESCSNGKRKQSLIDADHEEQALK 581
                      ::...||:.|.|.:|
  Rat   534 ----------EEEFYDANEETQMIK 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_650819.1	2A0119	11..509	CDD:273328	127/518 (25%)
Slc22a15	NP_001101177.1	MFS_SLC22A15	71..469	CDD:340935	104/422 (25%)