DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6231 and SPAPB1E7.08c

DIOPT Version :9

Sequence 1:	NP_001262734.1	Gene:	CG6231 / 42339	FlyBaseID:	FBgn0038720	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_594134.1	Gene:	SPAPB1E7.08c / 2543660	PomBaseID:	SPAPB1E7.08c	Length:	554	Species:	Schizosaccharomyces pombe

Alignment Length:	566	Identity:	121/566 - (21%)
Similarity:	201/566 - (35%)	Gaps:	160/566 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 FNRYQFMILALFGFINIIVSMHYFTQTVISFVPDH-WCYHDKLVNMTYKEIGEIYAQFENPSCT- 75
            |.|||:.:..:.||               .::.|: |                       |.||
pombe    74 FGRYQWYLFFVAGF---------------GWMSDNIW-----------------------PVCTS 100

  Fly    76 ----RLDDINGHNVTVSSKACEKWIYNYDFGYRSMNTELNWVCDSAYKARIGQSLFFIGSVVGTL 136
                |||:::|.:.....:|          .|.:::..|                   |.:||.:
pombe   101 LILMRLDEVDGPHPPAEGRA----------PYLTLSQNL-------------------GLLVGAM 136

  Fly   137 FYGLLSDKIGRVPALILSNFCGFAGDFSTIFTKSVATFTLCRF-------ISG-LAADTNFYLMY 193
            .:.|.:|.|||..|..|:..  |.|.|:.|...|....::|.|       :.| |..|:..:|..
pombe   137 VWSLSADTIGRRWAFNLTFL--FTGVFAVIAGASPNFASICVFDALWSFGVGGNLPVDSAIFLEA 199

  Fly   194 IIVLEYIRPSMRTLGLNMAVGLFYCLGLV---FTPWLAV---------LVGH------WQIYLAC 240
            :       ||.....|.: :..::.:|.|   ...|..:         .|.|      |:.:|..
pombe   200 L-------PSSHQWLLTV-MSFWWAIGQVIANLVSWGLISNFSCPDDESVCHRADNKGWRYFLFT 256

  Fly   241 TSLPILLVVLYYFVVQ--ESAQWLVTRNDIDGAIVRLKRVAKFNG--CRVSQADFDEFRRHCQMT 301
            .....||:....|:|.  ||.::.:.:.|...|:..:.::|:.||  |.::..:.....|..|..
pombe   257 MGGMTLLMFAARFLVSVYESPKFYLAKGDDYKAVETIHKIARINGKTCTLTVEELYAIDRQEQEE 321

  Fly   302 HEMLGGDDKK--------QAT---------------LLDMFRTPRMRKNTLILFFKSMVITLCYD 343
            .::   ||.|        |.|               :...|.:.::..:::::.....||.|.:.
pombe   322 SDL---DDSKSSDAKSVTQGTTNLIVEKLRKYNFEHIRQCFGSRKLAISSILVILSWAVIGLAFP 383

  Fly   344 AVSRNV-----------EGMGISPFIMFSL--SALAVLPSSVLLVLLQDRIGRKGMASGSLLVGG 395
            ..:..:           |.:.::.....||  ||:.|..|.:..||::.||||||....||::.|
pombe   384 LYNAFLPYYLETRGNANEPLSVAKTYRNSLIVSAIGVPGSLIAGVLVEFRIGRKGTLCLSLILTG 448

  Fly   396 LFTAAAGIAIAYQQHNHNAILLACLTIAARFGVAISYESGSQYATELIPTCVRGQGVAAVHVAGF 460
            :|..|:..|     ...||.|....|.:  |...|.|.....|..|:.|:.|||..|.....|..
pombe   449 VFLFASTTA-----KTSNAYLGWNCTFS--FFSDIMYGVLYAYTPEVFPSKVRGTAVGLAASANR 506

  Fly   461 AASFLAPYILWLGTFFKAAPSIILGVLF-FAGSFVCLLLPETLNRS 505
            .....:|.|........:||..:.|.|| |||..|.....|...:|
pombe   507 ILGIFSPVIAMRANLTTSAPIFVSGALFIFAGILVVFFPYEPRGKS 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	121/566 (21%)
CG6231	NP_001262734.1	MFS	125..499	CDD:119392	101/440 (23%)
SPAPB1E7.08c	NP_594134.1	2A0109	68..552	CDD:129965	120/564 (21%)
SPAPB1E7.08c	NP_594134.1	MFS	122..545	CDD:119392	103/461 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	79	1.000	Domainoid score	I2349
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I1789
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050