Protein Alignment CG6231 and Slc22a12

DIOPT Version :9

• Sequence 1: NP_001262734.1
• Gene: CG6231 / 42339
• FlyBaseID: FBgn0038720
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_033229.3
• Gene: Slc22a12 / 20521
• MGIID: 1195269
• Length: 553
• Species: Mus musculus
• Alignment Length: 591
• Identity: 147/591 - (24%)
• Similarity: 237/591 - (40%)
• Gaps: 141/591 - (23%)

  Fly     1 MDFDQILAKCGDFNRYQ-FMILALFGFINIIVSMHYFTQTVISFVPDHWCYHDKLVNMTYK---- 60
            |.|.::|.:.|...|:| |..:||...| :.|:.....:...:.||.|.|:...|.|.|.:
Mouse     1 MAFPELLDRVGGLGRFQLFQTVALVTPI-LWVTTQNMLENFSAAVPHHRCWVPLLDNSTSQASIP 64

  Fly    61 -EIG-EIYAQFENP--------SCTRLD----DINGHNVT------VSSKACEK-WIYNYDFGYR 104
             ::| ::......|        .|.|..    .:...|.|      .:::.||. |:|::.....
Mouse    65 GDLGPDVLLAVSIPPGPDQQPHQCLRFRQPQWQLTESNATATNWSDAATEPCEDGWVYDHSTFRS 129

  Fly   105 SMNTELNWVCDSAYKARIGQSLFFIGSVVGTLFYGLLSDKIGRVPAL----ILSNFCGFAGDFST 165
            ::.|..:.||:|.....:.||:|..|.:||....|..||:.||...|    :|.:..|.|..|..
Mouse   130 TIVTTWDLVCNSQALRPMAQSIFLAGILVGAAVCGHASDRFGRRRVLTWSYLLVSVSGTAAAFMP 194

  Fly   166 IF-TKSVATFTLCRFISGLAADTNFYLMYIIVLEYI----RPSMRTLGLNMAVGLFYCLGLVFTP 225
            .| ...:..|.|...::|:..:|...||     |:.    .|.:.||.   |:|  :..|.|.|.
Mouse   195 TFPLYCLFRFLLASAVAGVMMNTASLLM-----EWTSAQGSPLVMTLN---ALG--FSFGQVLTG 249

  Fly   226 WLAVLVGHWQIYLACTSLPILLVVLYYFVVQESAQWLVTRNDIDGAIVRLKRVAKFNGCRVSQAD 290
            .:|..|..|::.....|.|..|..:|.:.:.|||:||:|...:|..:..|:|||..|. |.::.|
Mouse   250 SVAYGVRSWRMLQLAVSAPFFLFFVYSWWLPESARWLITVGKLDQGLQELQRVAAVNR-RKAEGD 313

  Fly   291 FDEFRRHCQMTHEML-------GGDDKKQATLLDMFRTPRMRKNTLILFFKSMVITLCYDA---- 344
                    .:|.|:|       ...||..|:|..:..||.:|..|:|    ||   ||:.|
Mouse   314 --------TLTMEVLRSAMEEEPSRDKAGASLGTLLHTPGLRHRTII----SM---LCWFAFGFT 363

  Fly   345 ---VSRNVEGMGISPFIMFSLSALAVLPSSVLLVLLQDRIGRK---------------------- 384
               ::.:::.:|.:.|::.:|..:...|.....:||..|:||:
Mouse   364 FYGLALDLQALGSNIFLLQALIGIVDFPVKTGSLLLISRLGRRLCQVSFLVLPGLCILSNILVPH 428

  Fly   385 --GMASGSLLV------GGLFTAAAGIAIAYQQHNHNAILLACLTIAARFGVAISYESGSQYATE 441
              |:...:|.|      ||.||                    |:||               :::|
Mouse   429 GMGVLRSALAVLGLGCLGGAFT--------------------CITI---------------FSSE 458

  Fly   442 LIPTCVRGQGVAAVHVAGFAASFLAPYILWLGTFFKAAPSIILGVLFFAGSFVCLLLPETLNRSL 506
            |.||.:|...|....||....:.|.|.:..||.:....|.::.||:........||||||.|..|
Mouse   459 LFPTVIRMTAVGLCQVAARGGAMLGPLVRLLGVYGSWMPLLVYGVVPVLSGLAALLLPETKNLPL 523

  Fly   507 PTTIEE 512
            |.||::
Mouse   524 PDTIQD 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6231	NP_001262734.1	2A0119	11..509	CDD:273328	142/576 (25%)
		MFS	125..499	CDD:119392	105/426 (25%)
Slc22a12	NP_033229.3	2A0119	11..526	CDD:273328	142/576 (25%)
		MFS	147..516	CDD:119392	106/429 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843324
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.950